| Identification |
|---|
| HMDB Protein ID
| CDBP03221 |
| Secondary Accession Numbers
| Not Available |
| Name
| Sarcoplasmic reticulum histidine-rich calcium-binding protein |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| HRC |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Sarcoplasmic reticulum lumen
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19q13.3 |
| SNPs
| HRC |
| Gene Sequence
|
>2100 bp
ATGGGCCACCATAGGCCATGGCTGCACGCTTCTGTCCTCTGGGCTGGGGTGGCCAGCCTG
CTCCTCCCCCCGGCCATGACCCAGCAGCTCAGAGGGGATGGGCTAGGCTTCAGAAACCGG
AACAACAGCACTGGAGTCGCCGGGCTCTCCGAGGAGGCATCAGCAGAGCTTCGCCACCAC
CTCCACAGCCCTAGAGACCATCCAGATGAGAACAAGGATGTTTCCACAGAGAATGGGCAT
CATTTCTGGAGCCACCCAGACCGTGAAAAGGAGGATGAAGATGTCTCCAAGGAATATGGG
CACCTACTCCCAGGCCACAGGTCCCAAGACCACAAAGTCGGAGATGAGGGTGTCTCAGGT
GAGGAGGTCTTTGCAGAGCATGGTGGGCAGGCCCGTGGGCACAGAGGCCACGGGAGTGAA
GACACGGAAGACTCAGCTGAGCACAGGCACCACCTCCCCAGCCACAGGAGCCACAGCCAT
CAAGACGAGGATGAGGATGAAGTTGTGTCCAGTGAGCATCACCATCATATCCTCAGGCAT
GGACACCGAGGCCATGATGGGGAAGATGATGAAGGAGAAGAGGAGGAGGAGGAGGAGGAG
GAGGAAGAGGAGGCCTCCACTGAGTATGGACACCAGGCCCACAGGCACCGAGGCCATGGG
AGTGAAGAGGATGAGGATGTCTCAGATGGACACCATCATCATGGCCCCAGCCACAGGCAC
CAAGGCCATGAAGAAGATGACGATGATGATGATGATGATGATGATGATGATGATGATGAT
GATGTCTCCATTGAATATAGACACCAGGCTCACAGGCACCAAGGCCACGGGATTGAAGAG
GATGAAGATGTCTCAGATGGACACCATCATCGCGACCCCAGCCACAGGCACCGAAGCCAT
GAAGAAGATGACAATGATGATGATGATGTCTCCACTGAGTATGGACACCAGGCCCACAGG
CACCAAGACCACAGAAAGGAAGAGGTTGAGGCTGTCTCAGGTGAACACCACCATCATGTC
CCTGACCACAGGCACCAAGGCCACAGAGACGAGGAAGAAGATGAGGATGTGTCCACTGAA
CGTTGGCACCAGGGTCCCCAACATGTCCACCATGGCCTTGTAGATGAGGAAGAGGAAGAA
GAGGAGATCACAGTCCAGTTCGGCCACTATGTTGCAAGCCACCAACCTCGAGGCCACAAG
AGTGATGAAGAGGACTTCCAAGATGAGTATAAAACAGAAGTCCCTCACCATCACCACCAC
AGAGTCCCCAGGGAGGAAGATGAGGAGGTCTCTGCTGAGCTTGGCCACCAGGCCCCCAGC
CACAGGCAAAGCCACCAAGATGAAGAAACTGGCCATGGTCAAAGAGGGTCCATCAAAGAG
ATGAGCCATCACCCCCCAGGACACACAGTGGTCAAGGATAGAAGCCATTTGAGGAAGGAT
GATTCTGAGGAGGAAAAGGAGAAGGAAGAGGACCCCGGCTCCCATGAGGAAGACGATGAA
AGTTCAGAGCAGGGAGAGAAAGGCACCCATCATGGCAGCCGGGACCAGGAAGATGAGGAG
GATGAGGAGGAAGGTCATGGCCTCAGCCTGAACCAGGAGGAGGAAGAAGAGGAAGACAAG
GAGGAGGAGGAGGAGGAAGAAGACGAGGAGAGGAGGGAAGAGAGGGCTGAGGTTGGGGCC
CCACTGAGCCCAGACCACAGCGAGGAGGAAGAGGAGGAGGAGGAGGGGCTGGAGGAAGAT
GAGCCCCGCTTCACCATCATCCCCAACCCACTGGACAGGAGAGAGGAGGCTGGAGGTGCC
TCCAGCGAGGAGGAAAGCGGTGAGGACACAGGTCCACAGGATGCTCAGGAGTATGGGAAC
TACCAGCCAGGGTCCCTGTGTGGCTACTGCTCCTTCTGCAATCGATGCACTGAATGTGAG
AGCTGTCACTGTGATGAGGAGAACATGGGTGAGCACTGCGACCAGTGCCAGCACTGTCAG
TTCTGCTATCTCTGCCCGCTGGTCTGCGAAACGGTCTGCGCTCCAGGAAGCTACGTTGAC
TATTTCTCCTCGTCCCTTTATCAGGCCCTGGCAGACATGCTGGAAACGCCGGAACCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 699 |
| Molecular Weight
| 80243.5 |
| Theoretical pI
| 4.36 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Sarcoplasmic reticulum histidine-rich calcium-binding protein
MGHHRPWLHASVLWAGVASLLLPPAMTQQLRGDGLGFRNRNNSTGVAGLSEEASAELRHH
LHSPRDHPDENKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLPGHRSQDHKVGDEGVSG
EEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRH
GHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRH
QGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSH
EEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTE
RWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHHHH
RVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKD
DSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDK
EEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEAGGA
SSEEESGEDTGPQDAQEYGNYQPGSLCGYCSFCNRCTECESCHCDEENMGEHCDQCQHCQ
FCYLCPLVCETVCAPGSYVDYFSSSLYQALADMLETPEP
|
| External Links |
|---|
| GenBank ID Protein
| 46854902 |
| UniProtKB/Swiss-Prot ID
| P23327 |
| UniProtKB/Swiss-Prot Entry Name
| SRCH_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC069795 |
| GeneCard ID
| HRC |
| GenAtlas ID
| HRC |
| HGNC ID
| HGNC:5178 |
| References |
|---|
| General References
| Not Available |