Cannabis Compound Database: Showing Protein Beta-2-syntrophin (CDBP03216)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03216

Secondary Accession Numbers

Not Available

Name

Beta-2-syntrophin

Description

Not Available

Synonyms

59 kDa dystrophin-associated protein A1 basic component 2
SNT3
SNTL
Syntrophin-3
Syntrophin-like

Gene Name

SNTB2

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein binding

Specific Function

Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN

GO Classification

Function
binding
protein binding

Cellular Location

Cytoplasm
Peripheral membrane protein
Cytoplasmic vesicle
Membrane
cytoskeleton
secretory vesicle membrane
Cell junction

Pathways

Name	SMPDB/Pathwhiz	KEGG
Muscle/Heart Contraction		Not Available
Acebutolol Action Pathway		Not Available
Alprenolol Action Pathway		Not Available
Atenolol Action Pathway		Not Available
Betaxolol Action Pathway		Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

16q22.1

SNPs

SNTB2

Gene Sequence

>1623 bp
ATGAGGGTAGCTGCGGCGACTGCGGCGGCTGGAGCGGGGCCGGCCATGGCGGTGTGGACG
CGGGCCACCAAAGCGGGGCTGGTGGAGCTGCTCCTGAGGGAGCGCTGGGTCCGAGTGGTG
GCCGAGCTGAGCGGGGAGAGCCTGAGCCTGACGGGCGACGCCGCCGCGGCCGAGCTGGAG
CCCGCTCTGGGACCCGCGGCCGCCGCCTTCAACGGCCTCCCAAACGGCGGCGGCGCGGGC
GACTCGCTGCCCGGGAGCCCAAGCCGCGGCCTGGGGCCCCCGAGCCCGCCGGCGCCGCCT
CGGGGCCCCGCGGGTGAGGCGGGCGCGTCGCCGCCCGTGCGCCGGGTGCGGGTGGTGAAG
CAAGAGGCGGGCGGCCTGGGCATCAGCATCAAGGGCGGCCGCGAGAACCGGATGCCGATC
CTCATCTCCAAGATCTTCCCCGGGCTGGCTGCCGACCAGAGCCGGGCGCTGCGGCTGGGC
GACGCCATCCTGTCGGTGAACGGCACCGACCTGCGCCAGGCCACCCACGACCAGGCCGTG
CAGGCGCTGAAGCGCGCGGGCAAGGAGGTGCTGCTGGAGGTCAAGTTCATCCGAGAAGTA
ACACCATATATCAAGAAGCCATCATTAGTATCAGATCTGCCGTGGGAAGGTGCAGCCCCC
CAGTCACCAAGCTTTAGTGGCAGTGAGGACTCTGGTTCGCCAAAACACCAGAACAGCACC
AAGGACAGGAAGATCATCCCTCTCAAAATGTGCTTTGCTGCTAGAAACCTAAGCATGCCG
GATCTGGAAAACAGATTGATAGAGCTACATTCTCCTGATAGCAGGAACACGTTGATCCTA
CGCTGCAAAGATACAGCCACAGCACACTCCTGGTTCGTAGCTATCCACACCAACATAATG
GCTCTCCTCCCACAGGTGTTGGCTGAACTCAACGCCATGCTTGGGGCAACCAGTACAGCA
GGAGGCAGTAAAGAGGTGAAGCATATTGCCTGGCTGGCAGAACAGGCAAAACTAGATGGT
GGAAGACAGCAATGGAGACCTGTCCTCATGGCTGTGACTGAGAAGGATTTGCTGCTCTAT
GACTGTATGCCGTGGACAAGAGATGCCTGGGCGTCACCATGCCACAGCTACCCACTTGTT
GCCACCAGGTTGGTTCATTCTGGCTCCGGATGTCGATCCCCCTCCCTTGGATCTGACCTT
ACATTTGCTACCAGGACAGGCTCTCGACAGGGCATTGAGATGCATCTCTTCAGGGTGGAG
ACACATCGGGATCTGTCATCCTGGACCAGGATACTTGTTCAGGGTTGCCATGCTGCTGCT
GAGCTGATCAAGGAAGTCTCTCTAGGCTGCATGTTAAATGGCCAAGAGGTGAGGCTTACT
ATTCACTATGAAAATGGGTTCACCATCTCAAGGGAAAATGGAGGCTCCAGCAGCATATTG
TACCGCTACCCCTTTGAAAGGCTGAAGATGTCTGCTGATGATGGCATCCGAAATCTATAC
TTGGATTTTGGTGGTCCCGAGGGAGAACTGACCATGGACCTGCACTCTTGTCCGAAGCCG
ATTGTATTTGTGTTGCACACGTTTTTATCGGCCAAAGTCACTCGTATGGGACTGCTTGTA
TGA

Protein Properties

Number of Residues

540

Molecular Weight

57949.0

Theoretical pI

9.07

Pfam Domain Function

PDZ (PF00595 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Beta-2-syntrophin
MRVAAATAAAGAGPAMAVWTRATKAGLVELLLRERWVRVVAELSGESLSLTGDAAAAELE
PALGPAAAAFNGLPNGGGAGDSLPGSPSRGLGPPSPPAPPRGPAGEAGASPPVRRVRVVK
QEAGGLGISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAV
QALKRAGKEVLLEVKFIREVTPYIKKPSLVSDLPWEGAAPQSPSFSGSEDSGSPKHQNST
KDRKIIPLKMCFAARNLSMPDLENRLIELHSPDSRNTLILRCKDTATAHSWFVAIHTNIM
ALLPQVLAELNAMLGATSTAGGSKEVKHIAWLAEQAKLDGGRQQWRPVLMAVTEKDLLLY
DCMPWTRDAWASPCHSYPLVATRLVHSGSGCRSPSLGSDLTFATRTGSRQGIEMHLFRVE
THRDLSSWTRILVQGCHAAAELIKEVSLGCMLNGQEVRLTIHYENGFTISRENGGSSSIL
YRYPFERLKMSADDGIRNLYLDFGGPEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV

External Links

GenBank ID Protein

5803177

UniProtKB/Swiss-Prot ID

Q13425

UniProtKB/Swiss-Prot Entry Name

SNTB2_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_006750.3

GeneCard ID