| Identification |
|---|
| HMDB Protein ID
| CDBP03209 |
| Secondary Accession Numbers
| Not Available |
| Name
| Secernin-1 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| SCRN1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in dipeptidase activity |
| Specific Function
| Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium |
| GO Classification
|
| Function |
| exopeptidase activity |
| catalytic activity |
| hydrolase activity |
| dipeptidase activity |
| peptidase activity |
| peptidase activity, acting on l-amino acid peptides |
| Process |
| metabolic process |
| macromolecule metabolic process |
| protein metabolic process |
| proteolysis |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7p14.3-p14.1 |
| SNPs
| SCRN1 |
| Gene Sequence
|
>1245 bp
ATGGCTGCAGCTCCTCCAAGTTACTGTTTTGTTGCCTTCCCTCCACGTGCTAAGGATGGT
CTGGTGGTATTTGGGAAAAATTCAGCCCGGCCCAGAGATGAAGTGCAAGAGGTTGTGTAT
TTCTCGGCTGCTGATCACGAACCGGAGAGCAAGGTTGAGTGCACTTACATTTCAATCGAC
CAAGTTCCAAGGACCTATGCCATAATGATAAGCAGACCCGCCTGGCTCTGGGGAGCAGAA
ATGGGAGCCAATGAACATGGAGTGTGCATAGCCAATGAAGCCATCAACACCAGAGAGCCA
GCTGCCGAGATAGAAGCCTTGCTGGGGATGGATCTGGTCAGGCTTGGTTTAGAAAGAGGG
GAAACAGCTAAAGAAGCCTTAGATGTCATTGTCTCCTTGTTGGAAGAACATGGACAAGGT
GGGAATTACTTTGAAGATGCAAACTCCTGCCACAGCTTCCAAAGTGCATATCTGATTGTG
GATCGTGATGAAGCCTGGGTGCTCGAGACCATAGGGAAGTACTGGGCTGCCGAGAAAGTC
ACAGAGGGAGTGAGGTGCATTTGCAGTCAGCTTTCGCTCACCACTAAGATGGATGCAGAG
CATCCGGAACTCAGGAGTTACGCTCAGAGCCAAGGTTGGTGGACGGGAGAGGGCGAGTTC
AATTTTTCCGAAGTCTTTTCTCCAGTTGAGGATCATCTAGACTGCGGTGCTGGCAAAGAC
AGCTTAGAAAAACAAGAAGAAAGCATCACAGTGCAGACTATGATGAACACCTTACGGGAC
AAAGCCAGCGGAGTGTGCATAGACTCTGAGTTTTTCCTCACCACAGCCAGTGGAGTGTCT
GTCCTGCCGCAGAATAGAAGCTCTCCGTGCATTCACTACTTCACTGGAACCCCTGATCCT
TCCAGGTCCATATTCAAGCCTTTCATCTTTGTTGATGACGTAAAACTTGTCCCCAAAACA
CAGTCTCCCTGTTTTGGGGATGACGACCCTGCCAAAAAGGAGCCTCGGTTCCAGGAGAAA
CCAGACCGCCGGCATGAGCTGTACAAAGCCCACGAGTGGGCACGTGCCATCATCGAAAGT
GACCAGGAGCAAGGTCGCAAGCTGAGGAGCACCATGCTGGAGCTGGAGAAGCAAGGCCTG
GAAGCCATGGAAGAAATCCTGACCAGCTCCGAGCCACTGGACCCTGCGGAAGTGGGGGAC
CTTTTCTATGACTGTGTTGACACGGAGATTAAGTTCTTTAAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 414 |
| Molecular Weight
| 46381.6 |
| Theoretical pI
| 4.39 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Secernin-1
MAAAPPSYCFVAFPPRAKDGLVVFGKNSARPRDEVQEVVYFSAADHEPESKVECTYISID
QVPRTYAIMISRPAWLWGAEMGANEHGVCIANEAINTREPAAEIEALLGMDLVRLGLERG
ETAKEALDVIVSLLEEHGQGGNYFEDANSCHSFQSAYLIVDRDEAWVLETIGKYWAAEKV
TEGVRCICSQLSLTTKMDAEHPELRSYAQSQGWWTGEGEFNFSEVFSPVEDHLDCGAGKD
SLEKQEESITVQTMMNTLRDKASGVCIDSEFFLTTASGVSVLPQNRSSPCIHYFTGTPDP
SRSIFKPFIFVDDVKLVPKTQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAIIES
DQEQGRKLRSTMLELEKQGLEAMEEILTSSEPLDPAEVGDLFYDCVDTEIKFFK
|
| External Links |
|---|
| GenBank ID Protein
| 90265801 |
| UniProtKB/Swiss-Prot ID
| Q12765 |
| UniProtKB/Swiss-Prot Entry Name
| SCRN1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB071705 |
| GeneCard ID
| SCRN1 |
| GenAtlas ID
| SCRN1 |
| HGNC ID
| HGNC:22192 |
| References |
|---|
| General References
| Not Available |