| Identification |
| HMDB Protein ID
| CDBP03208 |
| Secondary Accession Numbers
| Not Available |
| Name
| Calcium-binding mitochondrial carrier protein SCaMC-3 |
| Description
| Not Available |
| Synonyms
|
- Mitochondrial ATP-Mg/Pi carrier protein 2
- Mitochondrial Ca(2+)-dependent solute carrier protein 2
- Small calcium-binding mitochondrial carrier protein 3
- Solute carrier family 25 member 23
|
| Gene Name
| SLC25A23 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in transporter activity |
| Specific Function
| Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.
|
| GO Classification
|
| Biological Process |
| transmembrane transport |
| Cellular Component |
| integral to membrane |
| mitochondrial inner membrane |
| Component |
| membrane |
| cell part |
| organelle membrane |
| organelle inner membrane |
| mitochondrial inner membrane |
| Function |
| transporter activity |
| calcium ion binding |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| Molecular Function |
| calcium ion binding |
| Process |
| establishment of localization |
| transport |
| transmembrane transport |
|
| Cellular Location
|
- Mitochondrion inner membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| 19 |
| Locus
| 19p13.3 |
| SNPs
| SLC25A23 |
| Gene Sequence
|
>1407 bp
ATGCGGGGGAGCCCGGGCGACGCGGAGCGGCGGCAGCGCTGGGGTCGCCTGTTCGAGGAG
CTGGACAGTAACAAGGATGGCCGCGTGGACGTGCACGAGTTGCGCCAGGGGCTGGCCAGG
CTGGGCGGGGGCAACCCAGACCCCGGCGCCCAACAGGGTATCTCCTCTGAGGGTGATGCT
GACCCAGATGGCGGGCTCGACCTGGAGGAATTTTCCCGCTATCTGCAGGAGCGGGAACAG
CGTCTGCTGCTCATGTTTCACAGTCTTGACCGGAACCAGGATGGTCACATTGATGTCTCT
GAGATCCAACAGAGTTTCCGAGCTCTGGGCATTTCCATCTCGCTGGAGCAGGCTGAGAAA
ATTTTGCACAGCATGGACCGAGACGGCACAATGACCATTGACTGGCAAGAATGGCGCGAC
CACTTCCTGTTGCATTCGCTGGAAAATGTGGAGGACGTGCTGTATTTCTGGAAGCATTCC
ACGGTCCTGGACATTGGCGAGTGCCTGACAGTGCCGGACGAGTTCTCAAAGCAAGAGAAG
CTGACGGGCATGTGGTGGAAACAGCTGGTGGCCGGCGCAGTGGCAGGTGCCGTGTCACGG
ACAGGCACGGCCCCTCTGGACCGCCTCAAGGTCTTCATGCAGGTCCATGCCTCAAAGACC
AACCGGCTGAACATCCTTGGGGGGCTTCGAAGCATGGTCCTTGAGGGAGGCATCCGCTCC
CTGTGGCGCGGCAATGGTATTAATGTACTCAAGATTGCCCCCGAGTCAGCTATCAAGTTC
ATGGCCTATGAACAGATCAAGAGGGCCATCCTGGGGCAGCAGGAGACACTGCATGTGCAG
GAGCGCTTCGTGGCTGGCTCCCTGGCTGGTGCCACAGCCCAAACCATCATTTACCCTATG
GAGGTGCTGAAGACGCGGCTGACCTTGCGCCGGACGGGCCAGTATAAGGGGCTGCTGGAC
TGCGCCAGGCGTATCCTGGAGAGGGAGGGGCCCCGTGCCTTCTACCGCGGCTACCTCCCC
AACGTGCTGGGCATCATCCCCTATGCGGGCATCGACCTGGCCGTCTACGAGACTCTGAAG
AACTGGTGGCTTCAGCAGTACAGCCACGACTCGGCAGACCCAGGCATCCTCGTGCTCCTG
GCCTGCGGTACCATATCCAGCACCTGCGGCCAGATAGCCAGTTACCCGCTGGCCCTGGTC
CGGACCCGCATGCAGGCACAAGCCTCCATCGAGGGTGGCCCCCAGCTGTCCATGCTGGGT
CTGCTACGTCACATCCTGTCCCAGGAGGGCATGCGGGGCCTCTACCGGGGGATCGCCCCC
AACTTCATGAAGGTTATTCCAGCTGTGAGCATCTCCTATGTGGTCTACGAGAACATGAAG
CAGGCCTTGGGGGTCACGTCCAGGTGA
|
| Protein Properties |
| Number of Residues
| 468 |
| Molecular Weight
| 52377.545 |
| Theoretical pI
| 7.327 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Calcium-binding mitochondrial carrier protein SCaMC-3
MRGSPGDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDA
DPDGGLDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEK
ILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEK
LTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRS
LWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPM
EVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLK
NWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLG
LLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR
|
| External Links |
| GenBank ID Protein
| 48476342 |
| UniProtKB/Swiss-Prot ID
| Q9BV35 |
| UniProtKB/Swiss-Prot Entry Name
| SCMC3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_024103.2 |
| GeneCard ID
| SLC25A23 |
| GenAtlas ID
| SLC25A23 |
| HGNC ID
| HGNC:19375 |
| References |
| General References
| Not Available |