| Identification |
| HMDB Protein ID
| CDBP03206 |
| Secondary Accession Numbers
| Not Available |
| Name
| Calcium-binding mitochondrial carrier protein SCaMC-1 |
| Description
| Not Available |
| Synonyms
|
- Mitochondrial ATP-Mg/Pi carrier protein 1
- Mitochondrial Ca(2+)-dependent solute carrier protein 1
- Small calcium-binding mitochondrial carrier protein 1
- Solute carrier family 25 member 24
|
| Gene Name
| SLC25A24 |
| Protein Type
| Metal Binding |
| Biological Properties |
| General Function
| Involved in calcium ion binding |
| Specific Function
| Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.
|
| GO Classification
|
| Biological Process |
| transmembrane transport |
| Cellular Component |
| integral to membrane |
| mitochondrial inner membrane |
| Component |
| membrane |
| cell part |
| organelle membrane |
| organelle inner membrane |
| mitochondrial inner membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Molecular Function |
| calcium ion binding |
| Process |
| transmembrane transport |
| establishment of localization |
| transport |
|
| Cellular Location
|
- Mitochondrion inner membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| 1 |
| Locus
| 1p13.3 |
| SNPs
| SLC25A24 |
| Gene Sequence
|
>1434 bp
ATGTTGCGCTGGCTGCGGGACTTCGTGCTGCCCACCGCGGCCTGCCAGGACGCGGAGCAG
CCGACGCGCTACGAGACCCTCTTCCAGGCACTGGACCGCAATGGGGACGGAGTGGTGGAC
ATCGGCGAGCTGCAGGAGGGGCTCAGGAACCTGGGCATCCCTCTGGGCCAGGACGCCGAG
GAGAAAATTTTTACTACTGGAGATGTCAACAAAGATGGGAAGCTGGATTTTGAAGAATTT
ATGAAGTACCTTAAAGACCATGAGAAGAAAATGAAATTGGCATTTAAGAGTTTAGACAAA
AATAATGATGGAAAAATTGAGGCTTCAGAAATTGTCCAGTCTCTCCAGACACTGGGTCTG
ACTATTTCTGAACAACAAGCAGAGTTGATTCTTCAAAGCATTGATGTTGATGGGACAATG
ACAGTGGACTGGAATGAATGGAGAGACTACTTCTTATTTAATCCTGTTACAGACATTGAG
GAAATTATCCGTTTCTGGAAACATTCTACAGGAATTGACATAGGGGATAGCTTAACTATT
CCAGATGAATTCACGGAAGACGAAAAAAAATCCGGACAATGGTGGAGGCAGCTTTTGGCA
GGAGGCATTGCTGGTGCTGTCTCTCGAACAAGCACTGCCCCTTTGGACCGTCTGAAAATC
ATGATGCAGGTTCACGGTTCAAAATCAGACAAAATGAACATATTTGGTGGCTTTCGACAG
ATGGTAAAAGAAGGAGGTATCCGCTCGCTTTGGAGGGGAAATGGTACAAACGTCATCAAA
ATTGCTCCTGAGACAGCTGTTAAATTCTGGGCATATGAACAGTACAAGAAGTTACTTACT
GAAGAAGGACAAAAAATAGGAACATTTGAGAGATTTATTTCTGGTTCCATGGCTGGAGCA
ACTGCACAGACTTTTATATATCCAATGGAGGTTATGAAAACCAGGCTGGCTGTAGGCAAA
ACTGGGCAGTACTCTGGAATATATGATTGTGCCAAGAAGATTTTGAAACATGAAGGCTTG
GGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCATACCTTATGCAGGCATA
GATCTTGCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCT
GTAAACCCTGGAGTCATGGTGTTGCTGGGATGCGGTGCCTTATCCAGCACCTGTGGTCAG
CTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGCTCAAGCCATGTTAGAA
GGTTCCCCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATA
CCAGGACTTTACAGAGGCATCACCCCAAACTTCATGAAGGTGCTCCCTGCTGTAGGCATC
AGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAACCCAGAAATGA
|
| Protein Properties |
| Number of Residues
| 477 |
| Molecular Weight
| 53354.08 |
| Theoretical pI
| 6.33 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Calcium-binding mitochondrial carrier protein SCaMC-1
MLRWLRDFVLPTAACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE
EKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL
TISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI
PDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQ
MVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGA
TAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI
DLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLE
GSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK
|
| External Links |
| GenBank ID Protein
| 148491091 |
| UniProtKB/Swiss-Prot ID
| Q6NUK1 |
| UniProtKB/Swiss-Prot Entry Name
| SCMC1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_013386.3 |
| GeneCard ID
| SLC25A24 |
| GenAtlas ID
| SLC25A24 |
| HGNC ID
| HGNC:20662 |
| References |
| General References
| Not Available |