| Identification |
|---|
| HMDB Protein ID
| CDBP03205 |
| Secondary Accession Numbers
| Not Available |
| Name
| Secretogranin-2 |
| Description
| Not Available |
| Synonyms
|
- Chromogranin-C
- SN
- Secretogranin II
- Secretoneurin
- SgII
|
| Gene Name
| SCG2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in chemoattractant activity |
| Specific Function
| Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 2q35-q36 |
| SNPs
| SCG2 |
| Gene Sequence
|
>1854 bp
ATGGCTGAAGCAAAGACCCACTGGCTTGGAGCAGCCCTGTCTCTTATCCCTTTAATTTTC
CTCATCTCTGGGGCTGAAGCAGCTTCATTTCAGAGAAACCAGCTGCTTCAGAAAGAACCA
GACCTCAGGTTGGAAAATGTCCAAAAGTTTCCCAGTCCTGAAATGATCAGGGCTTTGGAG
TACATAGAAAACCTCCGACAACAAGCTCATAAGGAAGAAAGCAGCCCAGATTATAATCCC
TACCAAGGTGTCTCTGTCCCCCTTCAGCAAAAAGAAAATGGCGATGAAAGCCACTTGCCC
GAGAGGGATTCACTGAGTGAAGAAGACTGGATGAGAATAATACTCGAAGCTTTGAGACAG
GCTGAAAATGAGCCTCAGTCTGCACCAAAAGAAAATAAGCCCTATGCCTTGAATTCAGAA
AAGAACTTTCCAATGGACATGAGTGATGATTATGAGACACAGCAGTGGCCAGAAAGAAAG
CTTAAGCACATGCAATTCCCTCCTATGTATGAAGAGAATTCCAGGGATAACCCCTTTAAA
CGCACAAATGAAATAGTGGAGGAACAATATACTCCTCAAAGCCTTGCTACATTGGAATCT
GTCTTCCAAGAGCTGGGGAAACTGACAGGACCAAACAACCAGAAACGTGAGAGGATGGAT
GAGGAGCAAAAACTTTATACGGATGATGAAGATGATATCTACAAGGCTAATAACATTGCC
TATGAAGATGTGGTCGGGGGAGAAGACTGGAACCCAGTAGAGGAGAAAATAGAGAGTCAA
ACCCAGGAAGAGGTGAGAGACAGCAAAGAGAATATAGAAAAAAATGAACAAATCAACGAT
GAGATGAAACGCTCAGGGCAGCTTGGCATCCAGGAAGAAGATCTTCGGAAAGAGAGTAAA
GACCAACTCTCAGATGATGTCTCCAAAGTAATTGCCTATTTGAAAAGGTTAGTAAATGCT
GCAGGAAGTGGGAGGTTACAGAATGGGCAAAATGGGGAAAGGGCCACCAGGCTTTTTGAG
AAACCTCTTGATTCTCAGTCTATTTATCAGCTGATTGAAATCTCAAGGAATTTACAGATA
CCCCCAGAAGACTTAATTGAGATGCTCAAAACTGGGGAGAAGCCGAATGGATCAGTGGAA
CCGGAGCGGGAGCTTGACCTTCCTGTTGACCTAGATGACATCTCAGAGGCTGACTTAGAC
CATCCAGACCTGTTCCAAAATAGGATGCTCTCCAAGAGTGGCTACCCTAAAACACCTGGT
CGTGCTGGGACTGAGGCCCTACCAGACGGGCTCAGTGTTGAGGATATTTTAAATCTTTTA
GGGATGGAGAGTGCAGCAAATCAGAAAACGTCGTATTTTCCCAATCCATATAACCAGGAG
AAAGTTCTGCCAAGGCTCCCTTATGGTGCTGGAAGATCTAGATCGAACCAGCTTCCCAAA
GCTGCCTGGATTCCACATGTTGAAAACAGACAGATGGCATATGAAAACCTGAACGACAAG
GATCAAGAATTAGGTGAGTACTTGGCCAGGATGCTAGTTAAATACCCTGAGATCATTAAT
TCAAACCAAGTGAAGCGAGTTCCTGGTCAAGGCTCATCTGAAGATGACCTGCAGGAAGAG
GAACAAATTGAGCAGGCCATCAAAGAGCATTTGAATCAAGGCAGCTCTCAGGAGACTGAC
AAGCTGGCCCCGGTGAGCAAAAGGTTCCCTGTGGGGCCCCCGAAGAATGATGATACCCCA
AATAGGCAGTACTGGGATGAAGATCTGTTAATGAAAGTGCTGGAATACCTCAACCAAGAA
AAGGCAGAAAAGGGAAGGGAGCATATTGCTAAGAGAGCAATGGAAAATATGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 617 |
| Molecular Weight
| 70940.2 |
| Theoretical pI
| 4.39 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Secretogranin-2
MAEAKTHWLGAALSLIPLIFLISGAEAASFQRNQLLQKEPDLRLENVQKFPSPEMIRALE
YIENLRQQAHKEESSPDYNPYQGVSVPLQQKENGDESHLPERDSLSEEDWMRIILEALRQ
AENEPQSAPKENKPYALNSEKNFPMDMSDDYETQQWPERKLKHMQFPPMYEENSRDNPFK
RTNEIVEEQYTPQSLATLESVFQELGKLTGPNNQKRERMDEEQKLYTDDEDDIYKANNIA
YEDVVGGEDWNPVEEKIESQTQEEVRDSKENIEKNEQINDEMKRSGQLGIQEEDLRKESK
DQLSDDVSKVIAYLKRLVNAAGSGRLQNGQNGERATRLFEKPLDSQSIYQLIEISRNLQI
PPEDLIEMLKTGEKPNGSVEPERELDLPVDLDDISEADLDHPDLFQNRMLSKSGYPKTPG
RAGTEALPDGLSVEDILNLLGMESAANQKTSYFPNPYNQEKVLPRLPYGAGRSRSNQLPK
AAWIPHVENRQMAYENLNDKDQELGEYLARMLVKYPEIINSNQVKRVPGQGSSEDDLQEE
EQIEQAIKEHLNQGSSQETDKLAPVSKRFPVGPPKNDDTPNRQYWDEDLLMKVLEYLNQE
KAEKGREHIAKRAMENM
|
| External Links |
|---|
| GenBank ID Protein
| 62988856 |
| UniProtKB/Swiss-Prot ID
| P13521 |
| UniProtKB/Swiss-Prot Entry Name
| SCG2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AC012512 |
| GeneCard ID
| SCG2 |
| GenAtlas ID
| SCG2 |
| HGNC ID
| HGNC:10575 |
| References |
|---|
| General References
| Not Available |