| Identification |
|---|
| HMDB Protein ID
| CDBP03202 |
| Secondary Accession Numbers
| Not Available |
| Name
| Serum amyloid P-component |
| Description
| Not Available |
| Synonyms
|
- 9.5S alpha-1-glycoprotein
- SAP
- Serum amyloid P-component(1-203)
|
| Gene Name
| APCS |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in metal ion binding |
| Specific Function
| Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q21-q23 |
| SNPs
| APCS |
| Gene Sequence
|
>672 bp
ATGAACAAGCCGCTGCTTTGGATCTCTGTCCTCACCAGCCTCCTGGAAGCCTTTGCTCAC
ACAGACCTCAGTGGGAAGGTGTTTGTATTTCCTAGAGAATCTGTTACTGATCATGTAAAC
TTGATCACACCGCTGGAGAAGCCTCTACAGAACTTTACCTTGTGTTTTCGAGCCTATAGT
GATCTCTCTCGTGCCTACAGCCTCTTCTCCTACAATACCCAAGGCAGGGATAATGAGCTA
CTAGTTTATAAAGAAAGAGTTGGAGAGTATAGTCTATACATTGGAAGACACAAAGTTACA
TCCAAAGTTATCGAAAAGTTCCCGGCTCCAGTGCACATCTGTGTGAGCTGGGAGTCCTCA
TCAGGTATTGCTGAATTTTGGATCAATGGGACACCTTTGGTGAAAAAGGGTCTGCGACAG
GGTTACTTTGTAGAAGCTCAGCCCAAGATTGTCCTGGGGCAGGAACAGGATTCCTATGGG
GGCAAGTTTGATAGGAGCCAGTCCTTTGTGGGAGAGATTGGGGATTTGTACATGTGGGAC
TCTGTGCTGCCCCCAGAAAATATCCTGTCTGCCTATCAGGGTACCCCTCTCCCTGCCAAT
ATCCTGGACTGGCAGGCTCTGAACTATGAAATCAGAGGATATGTCATCATCAAACCCTTG
GTGTGGGTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 223 |
| Molecular Weight
| 25386.9 |
| Theoretical pI
| 6.52 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Serum amyloid P-component
MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS
DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS
SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD
SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
|
| External Links |
|---|
| GenBank ID Protein
| 55665341 |
| UniProtKB/Swiss-Prot ID
| P02743 |
| UniProtKB/Swiss-Prot Entry Name
| SAMP_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AL445528 |
| GeneCard ID
| APCS |
| GenAtlas ID
| APCS |
| HGNC ID
| HGNC:584 |
| References |
|---|
| General References
| Not Available |