Cannabis Compound Database: Showing Protein Sodium- and chloride-dependent transporter XTRP3 (CDBP03201)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03201

Secondary Accession Numbers

Not Available

Name

Sodium- and chloride-dependent transporter XTRP3

Description

Not Available

Synonyms

Sodium/imino-acid transporter 1
Solute carrier family 6 member 20
Transporter rB21A homolog

Gene Name

SLC6A20

Protein Type

Transporter

Biological Properties

General Function

Involved in neurotransmitter:sodium symporter activity

Specific Function

Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N- methylated amino acids

GO Classification

Component
integral to plasma membrane
membrane
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
transporter activity
neurotransmitter transporter activity
neurotransmitter:sodium symporter activity
transmembrane transporter activity
Process
establishment of localization
transport
neurotransmitter transport

Cellular Location

Multi-pass membrane protein
Apical cell membrane

Pathways

Name	SMPDB/Pathwhiz	KEGG
Kidney Function		Not Available
Glucose Transporter Defect (SGLT2)		Not Available
Hartnup Disorder		Not Available
Iminoglycinuria		Not Available
Lysinuric Protein Intolerance		Not Available

Gene Properties

Chromosome Location

Chromosome:3

Locus

3p21.3

SNPs

SLC6A20

Gene Sequence

>1779 bp
ATGGAGAAAGCGCGGCCGCTGTGGGCCAACTCGCTACAGTTCGTGTTCGCCTGCATCTCG
TACGCCGTGGGCCTGGGCAACGTGTGGCGATTCCCGTACCTGTGCCAGATGTACGGCGGA
GGTAGTTTCCTGGTCCCCTACATCATCATGCTTATCGTGGAGGGAATGCCGCTCTTGTAC
CTGGAACTGGCTGTGGGGCAGCGCATGCGGCAGGGCAGCATCGGCGCCTGGAGGACCATC
AGCCCGTACCTCAGTGGTGTCGGGGTCGCCAGCGTGGTGGTCTCTTTCTTCCTCTCCATG
TACTACAACGTCATCAACGCCTGGGCCTTCTGGTACCTCTTCCACTCCTTCCAGGATCCC
CTGCCGTGGTCTGTCTGCCCACTGAATGGTAACCACACGGGCTACGATGAGGAGTGTGAG
AAGGCGTCCTCCACACAGTACTTCTGGTACAGGAAAACCCTCAATATCTCGCCGTCCCTC
CAGGAGAACGGGGGTGTGCAGTGGGAGCCGGCGCTGTGCCTCCTCCTGGCCTGGCTGGTG
GTGTACCTGTGCATCCTGCGTGGCACCGAGTCCACTGGCAAGGTGGTGTATTTCACGGCG
TCACTGCCCTATTGCGTGCTCATCATCTACCTCATCAGGGGCCTCACGCTCCACGGAGCC
ACCAATGGCCTCATGTACATGTTCACTCCCAAGATAGAGCAGCTGGCCAACCCCAAGGCC
TGGATCAATGCAGCCACCCAGATCTTCTTCTCACTTGGCCTGGGCTTCGGCAGCCTGATC
GCCTTCGCCAGCTACAATGAGCCATCCAACAACTGCCAGAAGCACGCCATCATCGTGTCC
CTCATCAACAGCTTCACCTCCATATTTGCCAGCATTGTCACCTTCTCCATCTATGGCTTC
AAGGCCACCTTCAATTATGAAAACTGCTTGAAGAAGGTGAGTCTGCTGCTGACCAACACT
TTTGACCTTGAAGATGGCTTTTTGACAGCCAGCAACCTGGAGCAGGTGAAGGGCTACCTC
GCATCTGCCTACCCAAGCAAATACAGCGAGATGTTCCCGCAAATCAAAAACTGCAGCTTG
GAATCGGAGCTAGACACGGCCGTCCAGGGCACTGGCCTGGCATTCATCGTCTACACAGAG
GCCATTAAAAACATGGAGGTGTCCCAGCTGTGGTCGGTGCTCTACTTCTTCATGCTGCTG
ATGCTGGGCATTGGGAGCATGCTGGGGAACACAGCGGCCATCCTCACCCCTCTGACAGAC
AGCAAGATCATCTCCAGCCACCTGCCCAAGGAGGCCATCTCAGGTCTGGTGTGCCTTGTC
AACTGTGCCATTGGCATGGTGTTCACGATGGAGGCTGGGAACTACTGGTTTGACATATTC
AACGACTACGCGGCCACACTGTCCCTGCTGCTCATCGTGCTGGTGGAGACGATTGCCGTG
TGCTACGTGTACGGGCTGAGGAGATTTGAAAGTGACCTTAAGGCCATGACCGGCCGAGCT
GTGAGCTGGTACTGGAAGGTGATGTGGGCTGGCGTAAGCCCACTGCTGATTGTCAGCCTC
TTTGTCTTCTACCTGAGCGACTACATCCTCACGGGGACCCTGAAGTATCAAGCCTGGGAC
GCCTCCCAGGGCCAGCTCGTGACCAAAGATTACCCGGCCTATGCACTGGCTGTCATCGGG
CTGCTTGTGGCCTCCTCCACCATGTGCATCCCCCTGGCGGCCCTGGGGACTTTTGTTCAG
CGTCGCCTCAAGAGGGGAGACGCAGACCCCGTGGCCTGA

Protein Properties

Number of Residues

592

Molecular Weight

65913.3

Theoretical pI

6.63

Pfam Domain Function

SNF (PF00209 )

Signals

["None"]

Transmembrane Regions

["6-26", "43-63", "80-100", "166-186", "195-215", "242-262", "277-297", "390-410", "432-452", "466-486", "505-525", "555-575"]

Protein Sequence

>Sodium- and chloride-dependent transporter XTRP3
MEKARPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLY
LELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDP
LPWSVCPLNGNHTGYDEECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAWLV
VYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTPKIEQLANPKA
WINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVTFSIYGF
KATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSEMFPQIKNCSL
ESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTD
SKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAV
CYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVFYLSDYILTGTLKYQAWD
ASQGQLVTKDYPAYALAVIGLLVASSTMCIPLAALGTFVQRRLKRGDADPVA

External Links

GenBank ID Protein

11181770

UniProtKB/Swiss-Prot ID

Q9NP91

UniProtKB/Swiss-Prot Entry Name

S6A20_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_020208.3

GeneCard ID