| Identification |
|---|
| HMDB Protein ID
| CDBP03194 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protein S100-A1 |
| Description
| Not Available |
| Synonyms
|
- S-100 protein alpha chain
- S-100 protein subunit alpha
- S100 calcium-binding protein A1
|
| Gene Name
| S100A1 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites |
| GO Classification
|
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q21 |
| SNPs
| S100A1 |
| Gene Sequence
|
>285 bp
ATGGGCTCTGAGCTGGAGACGGCGATGGAGACCCTCATCAACGTGTTCCACGCCCACTCG
GGCAAAGAGGGGGACAAGTACAAGCTGAGCAAGAAGGAGCTGAAAGAGCTGCTGCAGACG
GAGCTCTCTGGCTTCCTGGATGCCCAGAAGGATGTGGATGCTGTGGACAAGGTGATGAAG
GAGCTAGACGAGAATGGAGACGGGGAGGTGGACTTCCAGGAGTATGTGGTGCTTGTGGCT
GCTCTCACAGTGGCCTGTAACAATTTCTTCTGGGAGAACAGTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 94 |
| Molecular Weight
| 10545.8 |
| Theoretical pI
| 4.13 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protein S100-A1
MGSELETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDVDAVDKVMK
ELDENGDGEVDFQEYVVLVAALTVACNNFFWENS
|
| External Links |
|---|
| GenBank ID Protein
| 36176 |
| UniProtKB/Swiss-Prot ID
| P23297 |
| UniProtKB/Swiss-Prot Entry Name
| S10A1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| X58079 |
| GeneCard ID
| S100A1 |
| GenAtlas ID
| S100A1 |
| HGNC ID
| HGNC:10486 |
| References |
|---|
| General References
| Not Available |