| Identification |
|---|
| HMDB Protein ID
| CDBP03187 |
| Secondary Accession Numbers
| Not Available |
| Name
| Repetin |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| RPTN |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium |
| GO Classification
|
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
|
| Cellular Location
|
- Secreted
- extracellular space
- extracellular matrix
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q21.3 |
| SNPs
| RPTN |
| Gene Sequence
|
>2355 bp
ATGGCTCAACTCCTGAATAGCATACTCAGTGTGATTGACGTATTCCACAAATATGCCAAA
GGGAATGGGGACTGTGCCTTACTATGCAAGGAAGAGTTGAAACAACTGCTCTTGGCTGAG
TTTGGAGACATCCTCCAGAGACCAAATGACCCAGAGACTGTGGAAACCATCTTGAACCTC
TTAGATCAAGACCGAGATGGACATATTGATTTTCATGAGTACCTCTTGTTGGTGTTCCAG
TTGGTCCAAGCCTGCTATCATAAGCTAGACAATAAGTCACATGGAGGCAGGACCTCACAG
CAAGAAAGGGGGCAGGAAGGAGCACAAGACTGTAAGTTCCCAGGAAACACAGGCAGACAA
CACAGACAGAGGCACGAGGAAGAAAGGCAGAACTCCCACCACAGTCAGCCTGAGAGACAA
GACGGAGATTCCCACCATGGTCAGCCTGAGAGACAAGACAGAGATTCCCACCATGGTCAG
TCTGAGAAACAAGACAGAGATTCCCACCACAGTCAGCCTGAGAGACAAGACAGAGATTCT
CACCACAATCAGTCTGAGAGACAAGACAAGGATTTCAGCTTTGATCAGTCAGAGAGACAA
AGTCAAGACTCCAGCTCTGGTAAAAAAGTGAGTCACAAATCTACCAGTGGCCAGGCTAAA
TGGCAGGGACATATCTTTGCCTTAAATCGGTGTGAAAAACCAATTCAGGATTCTCATTAT
GGTCAGTCTGAAAGACATACACAACAATCTGAAACACTTGGACAAGCCTCTCACTTTAAC
CAGACAAATCAACAGAAATCAGGCTCTTATTGTGGACAGTCTGAGAGGCTAGGTCAGGAA
TTAGGCTGTGGTCAGACAGACAGACAAGGCCAGAGTTCCCACTACGGTCAGACGGACAGA
CAAGACCAGAGTTATCATTATGGTCAGACAGACAGACAAGGCCAGAGTTCCCACTACAGT
CAGACGGACAGACAAGGCCAGAGTTCCCACTACAGTCAGCCAGACAGACAAGGTCAGAGT
TCCCACTATGGTCAAATGGACAGAAAAGGCCAGTGTTATCATTATGATCAGACAAACAGA
CAAGGCCAGGGTTCCCACTACAGTCAACCAAACAGACAAGGTCAGAGTTCCCACTATGGT
CAGCCAGACACACAAGATCAGAGTTCTCACTATGGTCAGACAGACAGACAAGACCAAAGT
TCTCACTATGGTCAGACAGAGAGACAAGGCCAGAGTTCCCACTACAGTCAGATGGACCGA
CAAGGCCAGGGTTCTCACTACGGTCAGACAGACAGACAAGGCCAGAGTTCCCACTATGGT
CAGCCAGACAGACAAGGCCAGAATTCCCACTATGGTCAGACAGACAGACAAGGCCAGAGT
TCCCACTATGGTCAGACAGACAGACAAGGCCAGAGTTCCCACTACAGTCAGCCAGACAAA
CAAGGCCAGAGTTCCCACTATGGTAAGATAGACAGACAAGACCAGAGTTATCATTATGGT
CAGCCAGACGGACAAGGCCAAAGTTCCCACTATGGTCAGACAGACAGACAAGGCCAGAGT
TTCCACTATGGTCAGCCAGACAGACAAGGCCAGAGTTCCCACTACAGTCAGATGGACAGA
CAAGGCCAGAGTTCCCACTATGGTCAGACAGACAGACAAGGCCAGAGTTCCCACTACGGT
CAGACAGACAGACAAGGCCAGAGCTATCATTATGGTCAGACAGACAGACAAGGCCAGAGT
TCCCACTATATTCAATCACAGACTGGGGAAATACAAGGGCAAAATAAGTACTTCCAAGGG
ACTGAAGGAACAAGAAAAGCCTCTTATGTTGAACAATCAGGAAGATCAGGGAGGCTAAGT
CAACAGACTCCAGGACAGGAAGGGTACCAAAACCAGGGACAGGGATTCCAGTCTAGGGAC
TCACAGCAGAACGGCCACCAGGTATGGGAGCCTGAAGAGGATAGCCAACATCACCAACAC
AAACTCTTAGCACAAATCCAACAAGAAAGACCACTTTGTCACAAAGGGAGAGACTGGCAA
TCATGCAGTAGTGAGCAGGGCCACAGACAGGCCCAGACCAGGCAGAGTCATGGTGAGGGG
CTGAGCCACTGGGCAGAGGAAGAGCAGGGCCATCAAACTTGGGATAGACACAGCCATGAG
AGTCAGGAAGGTCCATGTGGGACACAGGACAGGCGAACCCATAAAGATGAGCAGAACCAT
CAGAGACGAGACAGACAAACCCATGAACATGAGCAGAGCCATCAGAGACGAGACAGGCAA
ACCCATGAAGACAAGCAGAACCGTCAGAGACGAGACAGGCAAACCCATGAAGACGAGCAG
AACCATCAGAGATGA
|
| Protein Properties |
|---|
| Number of Residues
| 784 |
| Molecular Weight
| 90731.2 |
| Theoretical pI
| 6.92 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Repetin
MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL
LDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQ
HRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDS
HHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHY
GQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDR
QDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNR
QGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDR
QGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDK
QGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDR
QGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQG
TEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQH
KLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHE
SQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQ
NHQR
|
| External Links |
|---|
| GenBank ID Protein
| 220776493 |
| UniProtKB/Swiss-Prot ID
| Q6XPR3 |
| UniProtKB/Swiss-Prot Entry Name
| RPTN_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AL589986 |
| GeneCard ID
| RPTN |
| GenAtlas ID
| RPTN |
| HGNC ID
| HGNC:26809 |
| References |
|---|
| General References
| Not Available |