Showing Protein Pyroglutamylated RFamide peptide receptor (CDBP03175)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03175
Secondary Accession Numbers Not Available
Name Pyroglutamylated RFamide peptide receptor
Description Not Available
Synonyms
  1. AQ27
  2. G-protein coupled receptor 103
  3. Orexigenic neuropeptide QRFP receptor
  4. SP9155
Gene Name QRFPR
Protein Type Receptor
Biological Properties
General Function Involved in G-protein coupled receptor protein signaling pathway
Specific Function Receptor for the orexigenic neuropeptide QRFP. The activity of this receptor is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels
GO Classification
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
neuropeptide receptor activity
receptor activity
neuropeptide y receptor activity
molecular transducer activity
signal transducer activity
peptide receptor activity
peptide receptor activity, g-protein coupled
Process
signaling pathway
cell surface receptor linked signaling pathway
g-protein coupled receptor protein signaling pathway
signaling
Cellular Location
  1. Cell membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:4
Locus 4q27
SNPs QRFPR
Gene Sequence 
>1296 bp
ATGCAGGCGCTTAACATTACCCCGGAGCAGTTCTCTCGGCTGCTGCGGGACCACAACCTG
ACGCGGGAGCAGTTCATCGCAGTTCATCGCCTGCGACCGCTCGTCTACACCCCAGAGCTG
CCGGGACGCGCCAAGCTGGCCCTCGTGCTCACCGGCGTGCTCATCTTCGCCCTGGCGCTC
TTTGGCAATGCTCTGGTGTTCTACGTGGTGACCCGCAGCAAGGCCATGCGCACCGTCACC
AACATCTTTATCTGCTCCTTGGCGCTCAGTGACCTGCTCATCACCTTCTTCTGCATTCCC
GTCACCATGCTCCAGAACATTTCCGACAACTGGCTGGGGGGTGCTTTCATTTGCAAGATG
GTGCCATTTGTCCAGTCTACCGCTGTTGTGACAGAAATCCTCACTATGACCTGCATTGCT
GTGGAAAGGCACCAGGGACTTGTGCATCCTTTTAAAATGAAGTGGCAATACACCAACCGA
AGGGCTTTCACAATGCTAGGTGTGGTCTGGCTGGTGGCAGTCATCGTAGGATCACCCATG
TGGCACGTGCAACAACTTGAGATCAAATATGACTTCCTATATGAAAAGGAACACATCTGC
TGCTTAGAAGAGTGGACCAGCCCTGTGCACCAGAAGATCTACACCACCTTCATCCTTGTC
ATCCTCTTCCTCCTGCCTCTTATGGTGATGCTTATTCTGTACAGTAAAATTGGTTATGAA
CTTTGGATAAAGAAAAGAGTTGGGGATGGTTCAGTGCTTCGAACTATTCATGGAAAAGAA
ATGTCCAAAATAGCCAGGAAGAAGAAACGAGCTGTCATTATGATGGTGACAGTGGTGGCT
CTCTTTGCTGTGTGCTGGGCACCATTCCATGTTGTCCATATGATGATTGAATACAGTAAT
TTTGAAAAGGAATATGATGATGTCACAATCAAGATGATTTTTGCTATCGTGCAAATTATT
GGATTTTCCAACTCCATCTGTAATCCCATTGTCTATGCATTTATGAATGAAAACTTCAAA
AAAAATGTTTTGTCTGCAGTTTGTTATTGCATAGTAAATAAAACCTTCTCTCCAGCACAA
AGGCATGGAAATTCAGGAATTACAATGATGCGGAAGAAAGCAAAGTTTTCCCTCAGAGAG
AATCCAGTGGAGGAAACCAAAGGAGAAGCATTCAGTGATGGCAACATTGAAGTCAAATTG
TGTGAACAGACAGAGGAGAAGAAAAAGCTCAAACGACATCTTGCTCTCTTTAGGTCTGAA
CTGGCTGAGAATTCTCCTTTAGACAGTGGGCATTAA
Protein Properties
Number of Residues 431
Molecular Weight 49487.4
Theoretical pI 9.51
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["47-67", "82-102", "121-141", "163-183", "213-233", "272-292", "312-332"]
Protein Sequence 
>Pyroglutamylated RFamide peptide receptor
MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALAL
FGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKM
VPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPM
WHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYE
LWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSN
FEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQ
RHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSE
LAENSPLDSGH
GenBank ID Protein 37651191
UniProtKB/Swiss-Prot ID Q96P65
UniProtKB/Swiss-Prot Entry Name QRFPR_HUMAN
PDB IDs Not Available
GenBank Gene ID AB109629
GeneCard ID QRFPR
GenAtlas ID QRFPR
HGNC ID HGNC:15565
References
General References Not Available