| Identification |
|---|
| HMDB Protein ID
| CDBP03160 |
| Secondary Accession Numbers
| Not Available |
| Name
| Plastin-1 |
| Description
| Not Available |
| Synonyms
|
- I-plastin
- Intestine-specific plastin
|
| Gene Name
| PLS1 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in actin binding |
| Specific Function
| Actin-bundling protein in the absence of calcium |
| GO Classification
|
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| protein binding |
| cytoskeletal protein binding |
| actin binding |
| calcium ion binding |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3q23 |
| SNPs
| PLS1 |
| Gene Sequence
|
>1890 bp
ATGGAAAACAGTACTACTACCATTTCTCGGGAGGAGCTTGAAGAACTACAAGAGGCATTT
AATAAAATAGATATTGACAATAGTGGGTATGTCAGTGACTATGAACTTCAAGACCTGTTT
AAGGAAGCAAGCCTTCCTCTGCCTGGCTACAAGGTGCGCGAGATTGTGGAGAAAATTCTA
TCAGTTGCTGACAGCAACAAAGATGGCAAAATCAGTTTTGAAGAGTTTGTGTCACTAATG
CAAGAATTAAAAAGCAAAGATATCAGCAAAACATTCCGAAAAATAATTAACAAGAGGGAA
GGGATTACTGCTATTGGAGGAACTTCAACTATTTCCAGTGAGGGCACACAGCATTCTTAT
TCAGAGGAAGAAAAAGTGGCTTTTGTTAACTGGATAAACAAAGCCCTGGAGAATGACCCT
GACTGTAAGCATCTTATACCCATGAATCCCAATGATGATAGTCTTTTCAAGTCACTTGCA
GATGGCATCCTTCTTTGCAAAATGATCAACTTATCTGAACCAGATACAATTGATGAAAGA
GCCATCAATAAGAAAAAGCTCACGCCATTCACTATTTCTGAAAATTTAAACCTAGCTCTG
AATTCTGCCTCAGCCATTGGTTGTACAGTGGTCAACATTGGTGCATCAGATCTCAAAGAA
GGAAAACCTCACTTGGTCTTGGGACTTCTCTGGCAGATCATCAAAGTTGGCCTTTTTGCT
GATATTGAGATTTCCAGGAATGAAGCTCTGATTGCATTGTTAAATGAAGGTGAGGAACTA
GAGGAGCTGATGAAGCTTTCTCCCGAGGAATTACTGCTGCGATGGGTGAACTACCATCTG
ACCAATGCAGGATGGCATACCATCAGCAACTTCAGCCAAGACATTAAGGACTCGAGAGCC
TATTTTCATCTGCTTAATCAGATTGCCCCTAAAGGTGGGGAAGATGGACTTGCCATTGCC
ATTGACCTTTCAGGAATTAATGAGACAAATGACCTGAAGCGTGCTGGACTCATGCTTCAA
GAAGCAGATAAACTGGGCTGCAAACAGTTTGTTACTCCTGCAGATGTGGTTTCAGGCAAT
CCTAAACTTAATTTAGCTTTTGTAGCTAATTTGTTTAACACATACCCATGCCTGCACAAG
CCGAATAATAATGACATCGATATGAATTTACTGGAAGGAGAGAGCAAGGAAGAGAGAACA
TTTCGGAACTGGATGAATTCCTTGGGAGTCAACCCATACATTAATCATTTGTACAGTGAC
CTTGCAGATGCTTTAGTGATCTTTCAGCTCTATGAGATGATCCGAGTGCCAGTCAACTGG
AGCCATGTCAACAAACCTCCTTATCCTGCCCTTGGAGGGAACATGAAGAAGATTGAAAAC
TGTAACTATGCAGTGGAACTTGGGAAGAACAAGGCCAAATTCTCCTTGGTTGGCATTGCT
GGGCAGGACCTAAATGAAGGGAATTCAACACTTACCCTGGCATTGGTATGGCAGCTGATG
AGAAGGTACACATTGAATGTGTTATCGGATCTTGGAGAGGGTGAAAAAGTAAATGATGAA
ATTATAATTAAATGGGTCAATCAGACTCTTAAAAGTGCAAACAAAAAGACTTCTATTTCC
AGCTTCAAGGATAAATCTATAAGCACAAGTTTACCTGTCCTAGATTTAATAGATGCCATT
GCACCAAATGCAGTTCGTCAAGAAATGATCAGGAGAGAAAACTTATCTGATGAGGACAAG
CTGAACAATGCTAAATACGCCATTTCAGTTGCTCGAAAGATCGGTGCCCGGATATATGCA
TTACCTGATGACCTCGTAGAAGTGAAACCAAAGATGGTTATGACGGTGTTTGCATGCTTA
ATGGGAAAAGGACTGAACAGAATAAAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 629 |
| Molecular Weight
| 70252.7 |
| Theoretical pI
| 5.06 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Plastin-1
MENSTTTISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKIL
SVADSNKDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTSTISSEGTQHSY
SEEEKVAFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLCKMINLSEPDTIDER
AINKKKLTPFTISENLNLALNSASAIGCTVVNIGASDLKEGKPHLVLGLLWQIIKVGLFA
DIEISRNEALIALLNEGEELEELMKLSPEELLLRWVNYHLTNAGWHTISNFSQDIKDSRA
YFHLLNQIAPKGGEDGPAIAIDLSGINETNDLKRAGLMLQEADKLGCKQFVTPADVVSGN
PKLNLAFVANLFNTYPCLHKPNNNDIDMNLLEGESKEERTFRNWMNSLGVNPYINHLYSD
LADALVIFQLYEMIRVPVNWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIA
GQDLNEGNSTLTLALVWQLMRRYTLNVLSDLGEGEKVNDEIIIKWVNQTLKSANKKTSIS
SFKDKSISTSLPVLDLIDAIAPNAVRQEMIRRENLSDEDKLNNAKYAISVARKIGARIYA
LPDDLVEVKPKMVMTVFACLMGKGLNRIK
|
| External Links |
|---|
| GenBank ID Protein
| 158261655 |
| UniProtKB/Swiss-Prot ID
| Q14651 |
| UniProtKB/Swiss-Prot Entry Name
| PLSI_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK290316 |
| GeneCard ID
| PLS1 |
| GenAtlas ID
| PLS1 |
| HGNC ID
| HGNC:9090 |
| References |
|---|
| General References
| Not Available |