Showing Protein Polycystic kidney disease 2-like 1 protein (CDBP03154)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 6 compounds
Identification
HMDB Protein ID CDBP03154
Secondary Accession Numbers Not Available
Name Polycystic kidney disease 2-like 1 protein
Description Not Available
Synonyms
  1. Polycystin-2 homolog
  2. Polycystin-2L1
  3. Polycystin-L
  4. Polycystin-L1
Gene Name PKD2L1
Protein Type Enzyme
Biological Properties
General Function Involved in calcium ion binding
Specific Function May function as a subunit of an ion channel and act as a transducer of calcium-mediated signaling
GO Classification
Component
membrane
cell part
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 10q24
SNPs PKD2L1
Gene Sequence 
>2418 bp
ATGAATGCTGTGGGAAGTCCTGAGGGGCAGGAGCTGCAAAAGCTGGGGAGTGGAGCCTGG
GACAACCCCGCCTACAGTGGTCCCCCTTCCCCACACGGGACGCTGAGAGTCTGCACCATC
TCCAGCACGGGGCCTCTCCAGCCCCAACCCAAGAAGCCTGAAGATGAACCCCAGGAGACG
GCATACAGGACCCAGGTGTCCAGCTGCTGCCTCCATATCTGTCAAGGCATCAGAGGACTT
TGGGGAACAACCCTGACTGAGAACACAGCTGAGAACCGGGAACTTTATATCAAGACCACC
CTGAGGGAGCTGTTGGTATATATTGTGTTCCTGGTGGACATCTGTCTACTGACCTATGGA
ATGACAAGCTCCAGTGCTTATTACTACACCAAAGTGATGTCTGAGCTCTTCTTACATACT
CCATCAGACACTGGAGTCTCCTTTCAGGCCATCAGCAGCATGGCGGACTTCTGGGATTTT
GCCCAGGGCCCACTACTGGACAGTTTGTATTGGACCAAATGGTACAACAACCAGAGCCTG
GGCCATGGCTCCCACTCCTTCATCTACTATGAGAACATGCTGCTGGGGGTTCCGAGGCTG
CGGCAGCTAAAGGTCCGCAATGACTCCTGTGTGGTGCATGAAGACTTCCGGGAGGACATT
CTGAGCTGCTATGATGTCTACTCTCCAGACAAAGAAGAACAACTCCCCTTTGGGCCCTTC
AATGGCACAGCGTGGACATACCACTCGCAGGATGAGTTGGGGGGCTTCTCCCACTGGGGC
AGGCTCACAAGCTACAGCGGAGGTGGCTACTACCTGGACCTTCCAGGATCCCGACAGGGT
AGTGCAGAGGCTCTCCGGGCCCTTCAGGAGGGGCTGTGGCTGGACAGGGGCACTCGAGTG
GTGTTCATCGACTTCTCAGTCTACAATGCCAATATCAATCTTTTCTGTGTCCTGAGGCTG
GTGGTGGAGTTTCCAGCTACAGGAGGTGCCATCCCATCCTGGCAAATCCGCACAGTCAAG
CTGATCCGCTATGTCAGCAACTGGGACTTCTTTATCGTTGGCTGTGAGGTCATCTTCTGC
GTCTTCATCTTCTACTATGTGGTGGAAGAGATCCTGGAGCTCCACATTCACCGGCTTCGC
TACCTCAGCAGCATCTGGAACATACTGGACCTGGTGGTCATCTTGCTCTCCATTGTGGCT
GTGGGCTTCCACATATTCCGAACCCTCGAGGTGAATCGGCTCATGGGGAAGCTCCTGCAG
CAGCCAAACACGTATGCAGACTTTGAGTTCCTCGCCTTCTGGCAGACACAGTACAACAAC
ATGAATGCTGTCAACCTCTTCTTCGCCTGGATCAAGATATTCAAGTACATCAGCTTCAAC
AAAACCATGACCCAGCTCTCCTCCACGCTGGCCCGCTGTGCCAAGGACATCCTGGGCTTC
GCCGTCATGTTCTTCATTGTTTTCTTCGCCTATGCCCAACTCGGCTACCTGCTTTTCGGG
ACCCAAGTGGAAAACTTTAGCACTTTCATCAAGTGCATTTTCACTCAGTTCCGGATAATC
CTCGGGGACTTTGACTACAATGCTATCGACAATGCCAACCGCATCCTGGGCCCTGCCTAC
TTTGTCACCTATGTCTTCTTCGTCTTCTTCGTGCTCCTGAACATGTTCCTGGCCATCATC
AATGACACATATTCAGAGGTCAAGGAGGAGCTGGCTGGACAGAAGGATGAGCTGCAACTT
TCTGACCTCCTGAAACAGGGCTACAACAAGACCCTACTAAGACTGCGTCTGAGGAAGGAG
AGGGTTTCGGATGTGCAGAAGGTCCTGCAGGGTGGGGAGCAGGAGATCCAGTTTGAGGAT
TTCACCAACACCTTAAGGGAACTGGGACACGCAGAGCATGAAATCACTGAGCTCACGGCC
ACCTTCACCAAGTTTGACAGAGATGGGAATCGTATTCTGGATGAGAAGGAACAGGAAAAA
ATGCGACAGGACCTGGAGGAAGAGAGGGTGGCCCTCAACACTGAGATTGAGAAACTAGGC
CGATCTATTGTGAGCAGCCCACAAGGCAAATCGGGTCCAGAGGCTGCCAGAGCAGGAGGC
TGGGTTTCAGGAGAAGAATTCTACATGCTCACAAGGAGAGTTCTGCAGCTGGAGACTGTC
CTGGAAGGAGTAGTGTCCCAGATTGATGCTGTAGGCTCAAAGCTGAAAATGCTGGAGAGG
AAGGGGTGGCTGGCTCCCTCCCCAGGCGTGAAGGAACAAGCTATTTGGAAGCACCCGCAG
CCAGCCCCAGCTGTGACCCCAGACCCCTGGGGAGTCCAGGGTGGGCAGGAGAGTGAGGTT
CCCTATAAAAGAGAAGAGGAAGCCTTAGAGGAGAGGAGACTCTCCCGTGGTGAGATTCCA
ACGTTGCAGAGGAGTTAA
Protein Properties
Number of Residues 805
Molecular Weight 91981.2
Theoretical pI 5.16
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["104-124", "314-334", "348-368", "385-405", "477-497", "540-560"]
Protein Sequence 
>Polycystic kidney disease 2-like 1 protein
MNAVGSPEGQELQKLGSGAWDNPAYSGPPSPHGTLRVCTISSTGPLQPQPKKPEDEPQET
AYRTQVSSCCLHICQGIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYG
MTSSSAYYYTKVMSELFLHTPSDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSL
GHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPF
NGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRV
VFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFC
VFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQ
QPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGF
AVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAY
FVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKE
RVSDVQKVLQGGEQEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEK
MRQDLEEERVALNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETV
LEGVVSQIDAVGSKLKMLERKGWLAPSPGVKEQAIWKHPQPAPAVTPDPWGVQGGQESEV
PYKREEEALEERRLSRGEIPTLQRS
GenBank ID Protein 33598944
UniProtKB/Swiss-Prot ID Q9P0L9
UniProtKB/Swiss-Prot Entry Name PK2L1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_016112.2
GeneCard ID PKD2L1
GenAtlas ID PKD2L1
HGNC ID HGNC:9011
References
General References Not Available