Showing Protein Programmed cell death protein 6 (CDBP03151)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03151
Secondary Accession Numbers Not Available
Name Programmed cell death protein 6
Description Not Available
Synonyms
  1. Apoptosis-linked gene 2 protein
  2. Probable calcium-binding protein ALG-2
Gene Name PDCD6
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway. Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Cellular Location
  1. Nucleus
  2. Peripheral membrane protein
  3. Peripheral membrane protein
  4. Endoplasmic reticulum membrane
  5. Nucleus membrane
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5p15.33
SNPs PDCD6
Gene Sequence 
>576 bp
ATGGCCGCCTACTCTTACCGCCCCGGCCCTGGGGCCGGCCCTGGGCCTGCTGCAGGCGCG
GCGCTGCCGGACCAGAGCTTCCTGTGGAACGTTTTCCAGAGGGTCGATAAAGACAGGAGT
GGAGTGATATCAGACACCGAGCTTCAGCAAGCTCTCTCCAACGGCACGTGGACTCCCTTT
AATCCAGTGACTGTCAGGTCGATCATATCCATGTTTGACCGTGAGAACAAGGCCGGCGTG
AACTTCAGCGAGTTCACGGGTGTGTGGAAGTACATCACGGACTGGCAGAACGTCTTCCGC
ACGTACGACCGGGACAACTCCGGGATGATCGATAAGAACGAGCTGAAGCAGGCCCTCTCA
GGTTTCGGCTACCGGCTCTCTGACCAGTTCCACGACATCCTCATTCGAAAGTTTGACAGG
CAGGGACGGGGGCAGATCGCCTTCGACGACTTCATCCAGGGCTGCATCGTCCTGCAGAGG
TTGACGGATATATTCAGACGTTACGACACGGATCAGGACGGCTGGATTCAGGTGTCGTAC
GAACAGTACCTGTCCATGGTCTTCAGTATCGTATGA
Protein Properties
Number of Residues 191
Molecular Weight 21868.3
Theoretical pI 4.97
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Programmed cell death protein 6
MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPF
NPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALS
GFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSY
EQYLSMVFSIV
GenBank ID Protein 3342794
UniProtKB/Swiss-Prot ID O75340
UniProtKB/Swiss-Prot Entry Name PDCD6_HUMAN
PDB IDs
GenBank Gene ID AF035606
GeneCard ID PDCD6
GenAtlas ID PDCD6
HGNC ID HGNC:8765
References
General References Not Available