| Identification |
|---|
| HMDB Protein ID
| CDBP03143 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin gamma-C3 |
| Description
| Not Available |
| Synonyms
|
- PC-43
- PCDH-gamma-C3
- Protocadherin-2
- Protocadherin-43
|
| Gene Name
| PCDHGC3 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHGC3 |
| Gene Sequence
|
>2805 bp
ATGGTCCCAGAGGCCTGGAGGAGCGGACTGGTAAGCACCGGGAGGGTAGTGGGAGTTTTG
CTTCTGCTTGGTGCCTTGAACAAGGCTTCCACGGTCATTCACTATGAGATCCCGGAGGAA
AGAGAGAAGGGTTTCGCTGTGGGCAACGTGGTCGCGAACCTTGGTTTGGATCTCGGTAGC
CTCTCAGCCCGCAGGTTCCGGGTGGTGTCTGGAGCTAGCCGAAGATTCTTTGAGGTGAAC
CGGGAGACCGGAGAGATGTTTGTGAACGACCGTCTGGATCGAGAGGAGCTGTGTGGGACA
CTGCCCTCTTGCACTGTAACTCTGGAGTTGGTAGTGGAGAACCCGCTGGAGCTGTTCAGC
GTGGAAGTGGTGATCCAGGACATCAACGACAACAATCCTGCTTTCCCTACCCAGGAAATG
AAATTGGAGATTAGCGAGGCCGTGGCTCCGGGGACGCGCTTTCCGCTCGAGAGCGCGCAC
GATCCCGATGTGGGAAGCAACTCTTTACAAACCTATGAGCTGAGCCGAAATGAATACTTT
GCGCTTCGCGTGCAGACGCGGGAGGACAGCACCAAGTACGCGGAGCTGGTGTTGGAGCGC
GCCCTGGACCGAGAACGGGAGCCTAGTCTCCAGTTAGTGCTGACGGCGTTGGACGGAGGG
ACCCCAGCTCTCTCCGCCAGCCTGCCTATTCACATCAAGGTGCTGGACGCGAATGACAAT
GCGCCTGTCTTCAACCAGTCCTTGTACCGGGCGCGCGTCCTGGAGGATGCACCCTCCGGC
ACGCGCGTGGTACAAGTCCTTGCAACGGATCTGGATGAAGGCCCCAACGGTGAAATTATT
TACTCCTTCGGCAGCCACAACCGCGCCGGCGTGCGGCAACTATTCGCCTTAGACCTTGTA
ACCGGGATGCTGACAATCAAGGGTCGGCTGGACTTCGAGGACACCAAACTCCATGAGATT
TACATCCAGGCCAAAGACAAGGGCGCCAATCCCGAAGGAGCACATTGCAAAGTGTTGGTG
GAGGTTGTGGATGTGAATGACAACGCCCCGGAGATCACAGTCACCTCCGTGTACAGCCCA
GTACCCGAGGATGCCCCTCTGGGGACTGTCATCGCTTTGCTCAGTGTGACTGACCTGGAT
GCTGGCGAGAACGGGCTGGTGACCTGCGAAGTTCCACCGGGTCTCCCTTTCAGCCTTACT
TCTTCCCTCAAGAATTACTTCACTTTGAAAACCAGTGCAGACCTGGATCGGGAGACTGTG
CCAGAATACAACCTCAGCATCACCGCCCGAGACGCCGGAACCCCTTCCCTCTCAGCCCTT
ACAATAGTGCGTGTTCAAGTGTCCGACATCAATGACAACCCTCCACAATCTTCTCAATCT
TCCTACGACGTTTACATTGAAGAAAACAACCTCCCCGGGGCTCCAATACTAAACCTAAGT
GTCTGGGACCCCGACGCCCCGCAGAATGCTCGGCTTTCTTTCTTTCTCTTGGAGCAAGGA
GCTGAAACCGGGCTAGTGGGTCGCTATTTCACAATAAATCGTGACAATGGCATAGTGTCA
TCCTTAGTGCCCCTAGACTATGAGGATCGGCGGGAATTTGAATTAACAGCTCATATCAGC
GATGGGGGCACCCCGGTCCTAGCCACCAACATCAGCGTGAACATATTTGTCACTGATCGC
AATGACAATGCCCCCCAGGTCCTATATCCTCGGCCAGGTGGGAGCTCGGTGGAGATGCTG
CCTCGAGGTACCTCAGCTGGCCACCTAGTGTCACGGGTGGTAGGCTGGGACGCGGATGCA
GGGCACAATGCCTGGCTCTCCTACAGTCTCTTGGGATCCCCTAACCAGAGCCTTTTTGCC
ATAGGGCTGCACACTGGTCAAATCAGTACTGCCCGTCCAGTCCAAGACACAGATTCACCC
AGGCAGACTCTCACGGTCTTGATCAAAGACAATGGGGAGCCTTCGCTCTCCACCACTGCT
ACCCTCACTGTGTCAGTAACCGAGGACTCTCCTGAAGCCCGAGCCGAGTTCCCCTCTGGC
TCTGCCCCCCGGGAGCAGAAAAAAAATCTCACCTTTTATCTACTTCTTTCCCTAATCCTG
GTTTCTGTGGGGTTTGTGGTCACAGTGTTCGGAGTAATCATATTCAAAGTTTACAAGTGG
AAGCAGTCTAGAGACCTATACCGAGCCCCGGTGAGCTCACTGTACCGAACACCAGGGCCC
TCCTTGCACGCGGACGCCGTGCGGGGAGGCCTGATGTCGCCGCACCTTTACCATCAGGTG
TATCTCACCACGGACTCCCGCCCCGGCGACCCGCTGCTGAAGAAACCTGGTGCAGCCAGT
CCACTGGCCAGCCGCCAGAACACGCTGCGGAGCTGTGATCCGGTGTTCTATAGGCAGGTG
TTGGGTGCAGAGAGCGCCCCTCCCGGACAGCAAGCCCCGCCCAACACGGACTGGCGTTTC
TCTCAGGCCCAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGG
CCCAACAACCAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAA
GCTGCTGATGGGAGCTCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGC
TACGGACCCCAGTTCACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTACATCCCA
GGCAGCAATGCCACACTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCAGGT
GGCAATGGCAACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 934 |
| Molecular Weight
| 101076.5 |
| Theoretical pI
| 4.84 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin gamma-C3
MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS
LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS
VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF
ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN
APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV
TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP
VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV
PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS
VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS
DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA
GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA
TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW
KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS
PLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW
PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP
GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
|
| External Links |
|---|
| GenBank ID Protein
| 2995719 |
| UniProtKB/Swiss-Prot ID
| Q9UN70 |
| UniProtKB/Swiss-Prot Entry Name
| PCDGK_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF052685 |
| GeneCard ID
| PCDHGC3 |
| GenAtlas ID
| PCDHGC3 |
| HGNC ID
| HGNC:8716 |
| References |
|---|
| General References
| Not Available |