| Identification |
|---|
| HMDB Protein ID
| CDBP03139 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin gamma-B4 |
| Description
| Not Available |
| Synonyms
|
- Cadherin-20
- Fibroblast cadherin-2
- PCDH-gamma-B4
|
| Gene Name
| PCDHGB4 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| binding |
| calcium ion binding |
| ion binding |
| cation binding |
| metal ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHGB4 |
| Gene Sequence
|
>2772 bp
ATGGGGAGCGGCGCCGGGGAGCTGGGCCGGGCTGAGAGGCTGCCAGTGCTCTTTCTCTTC
CTGCTGTCTTTGTTCTGCCCGGCGCTCTGTGAGCAGATCCGCTACAGGATTCCCGAGGAA
ATGCCCAAGGGCTCCGTAGTGGGGAACCTCGCCACGGACCTGGGGTTCAGCGTCCAGGAG
TTACCGACTCGAAAACTGCGCGTCAGTTCGGAGAAGCCTTACTTCACCGTGAGCGCAGAG
AGCGGGGAGTTGCTTGTGAGCAGCAGGCTAGACAGGGAGGAGATATGCGGGAAGAAGCCA
GCTTGTGCTCTGGAATTTGAGGCTGTTGCTGAAAATCCACTGAACTTTTATCACGTGAAT
GTGGAGATCGAGGACATTAATGACCACACGCCAAAATTCACGCAAAATTCCTTTGAGCTG
CAAATAAGTGAGTCTGCACAGCCTGGCACACGATTTATATTAGGATCTGCCCATGATGCG
GATATTGGTAGCAACACACTGCAGAATTACCAACTCAGTCCCAGTGATCATTTCTCACTG
ATAAATAAAGAGAAATCAGATGGCAGTAAATACCCTGAGATGGTATTGAAGACACCTTTG
GACAGAGAAAAGCAGAAATCCTACCACTTGACTTTGACTGCCTTGGACTTTGGAGCTCCA
CCCCTAAGCAGCACTGCACAGATACACGTTCTAGTGACTGATGCCAATGATAATGCTCCA
GTGTTCAGTCAAGACGTATACAGGGTGAGCCTTTCAGAAAACGTGTACCCGGGGACCACG
GTGCTACAGGTGACTGCCACGGACCAGGATGAGGGTGTCAATGCCGAGATTACTTTCTCT
TTCAGTGAAGCTAGCCAGATCACCCAATTTGACCTGAACTCTAACACCGGGGAAATTACT
GTTTTAAATACATTAGATTTTGAAGAAGTCAAAGAATATTCCATAGTTTTGGAAGCAAGG
GACGGTGGAGGAATGATTGCGCAATGCACAGTGGAGGTAGAAGTCATAGATGAAAATGAC
AACGCCCCAGAAGTGATATTCCAGTCTCTACCCAACCTAATTATGGAGGACGCCGAGCTG
GGAACACATATTGCTTTGCTCAAAGTCCGTGACAAGGATTCCAGACACAATGGAGAAGTG
ACTTGTAAATTGGAAGGTGATGTTCCATTTAAAATATTAACTTCTTCAAGAAACACGTAT
AAATTAGTGACAGATGCTGTTCTAGACCGCGAGCAGAATCCAGAGTACAATATAACCGTT
ACGGCAACAGATCGGGGCAAGCCTCCCCTCTCCTCCAGTTCCAGCATCACCCTGCACATT
GGTGATGTAAATGACAACGCTCCGGTTTTCTCACAGTCTTCCTATATAGTCCACGTGGCC
GAGAACAACCCGCCTGGAGCCTCTATTTCACAAGTCAGGGCTTCTGATCCGGACTTGGGG
CCCAACGGCCAAGTCTCTTACTGCATCATGGCCAGTGACCTGGAGCAGCGGGAGCTGTCA
TCCTACGTGTCCATAAGCGCGGAGAGCGGGGTGGTGTTCGCGCAGCGCGCCTTCGACCAC
GAGCAGCTGCGCGCCTTCGAACTCACACTGCAGGCCCGCGACCAGGGCTCGCCAGCGCTC
AGCGCGAACGTGAGCCTGCGCGTGTTAGTGGACGACCGCAACGACAATGCGCCACGGGTG
CTGTACCCCGCGCTGGGTCCCGACGGCTCTGCGCTCTTCGATATGGTGCCGCACGCTGCA
GAGCCTGGCTACTTGGTGACCAAGGTAGTGGCGGTGGACGCAGACTCAGGACACAACGCC
TGGCTGTCCTACCACGTGCTGCAGGCTAGCGAGCCCGGGCTCTTCAGCCTGGGGCTGCGC
ACGGGCGAAGTGCGCACAGCGCGTGCCTTAGGCGACAGGGACGCCGTCCGCCAGCGCCTT
CTGGTCGCCGTGCGTGACGGTGGACAGCCACCACTCTCGGCCACTGCCACGTTGCACCTG
GTCTTCGCCGACAGCTTGCAGGAGGTGCTGCCGGATATCACTGACCGCCCCGACCCCTCT
GACCTCCAGGCTGAGCTGCAGTTTTACCTAGTGGTGGCCTTGGCCTTGATCTCAGTGCTC
TTCCTCGTGGCCATGATTCTGGCCATTGCCTTGCGCCTGCGACGCTCCTCCAGCCCCGCC
TCCTGGAGCTGCTTCCAGCCTGGTCTCTGTGTTAAATCCGAATCCGTGGTTCCCCCCAAC
TACAGCGAGGGGACTTTGCCTTATTCCTACAATCTATGTGTTGCACATACAGGAAAGACG
GAGTTTAATTTCCTAAAATGTAGTGAGCAGTTGAGTTCAGGACAAGACATACTTTGCGGT
GATTCATCTGGGGCCTTATTTCCACTTTGTAATTCCAGTGAATTGACTTCCCATCAGCAA
GCCCCGCCCAACACGGACTGGCGTTTCTCTCAGGCCCAGAGACCCGGCACCAGCGGCTCC
CAAAATGGCGATGACACCGGCACCTGGCCCAACAACCAGTTTGACACAGAGATGCTGCAA
GCCATGATCTTGGCGTCCGCCAGTGAAGCTGCTGATGGGAGCTCCACCCTGGGAGGGGGT
GCCGGCACCATGGGATTGAGCGCCCGCTACGGACCCCAGTTCACCCTGCAGCACGTGCCC
GACTACCGCCAGAATGTCTACATCCCAGGCAGCAATGCCACACTGACCAACGCAGCTGGC
AAGCGGGATGGCAAGGCCCCAGCAGGTGGCAATGGCAACAAGAAGAAGTCGGGCAAGAAG
GAGAAGAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 923 |
| Molecular Weight
| 99925.7 |
| Theoretical pI
| 4.55 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin gamma-B4
MGSGAGELGRAERLPVLFLFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQE
LPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHVN
VEIEDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSL
INKEKSDGSKYPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAP
VFSQDVYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEIT
VLNTLDFEEVKEYSIVLEARDGGGMIAQCTVEVEVIDENDNAPEVIFQSLPNLIMEDAEL
GTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITV
TATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASDPDLG
PNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGSPAL
SANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVDADSGHNA
WLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATATLHL
VFADSLQEVLPDITDRPDPSDLQAELQFYLVVALALISVLFLVAMILAIALRLRRSSSPA
SWSCFQPGLCVKSESVVPPNYSEGTLPYSYNLCVAHTGKTEFNFLKCSEQLSSGQDILCG
DSSGALFPLCNSSELTSHQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQ
AMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAG
KRDGKAPAGGNGNKKKSGKKEKK
|
| External Links |
|---|
| GenBank ID Protein
| 13470082 |
| UniProtKB/Swiss-Prot ID
| Q9UN71 |
| UniProtKB/Swiss-Prot Entry Name
| PCDGG_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_003736.2 |
| GeneCard ID
| PCDHGB4 |
| GenAtlas ID
| PCDHGB4 |
| HGNC ID
| HGNC:8711 |
| References |
|---|
| General References
| Not Available |