| Identification |
|---|
| HMDB Protein ID
| CDBP03137 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin gamma-B2 |
| Description
| Not Available |
| Synonyms
|
- PCDH-gamma-B2
|
| Gene Name
| PCDHGB2 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHGB2 |
| Gene Sequence
|
>2796 bp
ATGAAAGCGAGCTCAGGGAGGTGCGGGCTGGTGCGGTGGCTGCAGGTACTGTTGCCCTTC
CTGTTGTCTTTGTTCCCCGGGGCTCTCCCAGTCCAGATCCGCTATTCAATTCCAGAGGAG
CTGGCCAAAAACTCGGTCGTAGGAAACCTCGCCAAGGATCTGGGGCTCAGCGTCCGGGAC
TTGCCAGCCCGGAAGCTGCGGGTTAGCGCGGAGAAGGAATATTTCACAGTAAACCCAGAA
AGCGGAGACTTACTTGTGAGTGACAGAATAGACCGAGAACAGATATGCGGGAAGCAGCCT
CTGTGTGTTCTGGATTTCGATACTGTCGCTGAAAATCCACTAAATATTTTCTACATAGCA
GTAATTGTGCAGGATATAAATGATAATACCCCGCTATTCAAACAGACTAAGATTAATTTA
AAAATTGGCGAATCCACTAAGCCAGGTACAACATTTCCACTTGACCCAGCCCTGGATTCA
GATGTTGGTCCTAACTCACTACAAAGATACCACCTTAATGACAACGAGTACTTTGATCTC
GCTGAGAAACAGACTCCAGATGGTCGTAAATATCCTGAGTTGATTCTAAAACACTCTCTG
GACAGAGAAGAGCACAGTTTACATCAATTGGTCCTCACAGCTGTGGATGGCGGAGACCCA
CCTCAAAGTGGCACGACCCAAATCCGAATCAAAGTCACGGATGCCAACGATAACCCTCCA
GTGTTCAGCCAGGACGTGTACAGGGTCACCCTGAGGGAGGACGTGCCGCCGGGCTTCTTT
GTGCTTCAAGTGACAGCCACCGACCGGGATGAAGGCATAAACGCAGAGATCACCTACTCC
TTTCATAATGTGGACGAACAAGTGAAACACTTTTTCAACTTAAATGAAAAAACAGGAGAA
ATCACGACAAAGGATGATTTGGATTTTGAGATTGCAAGTAGTTACACTCTGAGTATCGAA
GCAAAAGATCCTGGAGATCTAGCAGCCCACTGCAGTATCCAAGTTGAAATTCTTGATGAC
AACGATTGTGCACCTGAAGTTATTGTGACTTCAGTATCTACTCCCCTACCGGAGGATTCG
CCACCAGGAACAGTGATCGCCTTGATAAAAACGAGAGACAGAGACTCTGGAGAAAATGGA
GAAGTTTACTGCCAAGTGTTGGGAAATGCCAAGTTTATTTTGAAATCTTCCTCAAAGAAC
TATTACAAACTAGTGACAGACGGCGCTCTGGACCGGGAGGAGATCCCAGAATACAATCTC
ACCATCACAGCCACCGACGGGGGCAAGCCGCCCCTCTCCTCCAGCATAATTGTCACCCTG
CACATCTCCGACGTCAACGATAATGCCCCAGTTTTCCAACAGACTTCCTACATGGTTCAC
GTGGCAGAGAACAATCCTCCTGGCGCCTCTATCGCTCAAATCAGTGCCTCTGACCCTGAC
TTGGGCCCCAGTGGCCAAGTTTCCTACTCCATCGTAGCGAGCGACCTGAAGCCGCGGGAG
ATTTTATCCTACGTGTCCGTGAGCGCGCAGAGCGGGGTGGTGTTCGCGCAGCGCGCCTTC
GATCATGAGCAGCTGCGCGCCTTCGAGCTCACACTGCAGGCCCGCGACCAGGGCTCGCCC
GCGCTCAGCGCCAACGTGAGCCTGCGCGTGTTAGTGGGCGACCTCAATGACAATGCGCCA
CGGGTGCTGTACCCCGCGCTGGGGCCTGATGGCTCCGCCCTCTTCGATATGGTGCCACGC
GCCGCAGAGCCCGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGCAGACTCAGGACAC
AACGCTTGGCTGTCCTACCACGTGCTGCAGGCCAGCGAGCCCGGGCTCTTCAGCCTGGGG
TTGCGCACGGGTGAGGTGCGCACAGCGCGTGCCTTGGGCGACAGGGACGCGGCCCGCCAG
CGCCTGCTGGTCGCTGTGCGTGATGGAGGACAGCCGCCACTCTCCGCTACGGCCACGCTG
CACCTAATCTTCGCGGATAGCCTGCAAGAGGTATTGCCAGACCTCAGCGACCGCCGGGAG
CCCTCTGACCCCCAGGCAAAACTGCAGTTTTACCTGGTTGTGGCCTTGGCCTTGATCTCA
GTGCTCTTCTTCCTCGCGGTGATTCTGGCAATCTCCCTGCGCCTGCGACTCTCTTCCAGG
TCAGATGCTTGGGACTGTTTTCAGCCTGGTCTCAGCTCCAAGCCTGGACCTGGGGTTCTC
CCCAATTACAGTGAGGGTACATTGCCCTATTCCTACAACCTGTGTGTTGCCTCACAATCA
GCCAAGACAGAGTTCAATTTTCTGAACATAACCCCGGAATTGGTTCCCGCGCAAGATCTC
GTCTGTGACAATGCCTCTTGGGAACAAAATACAAATCATGGAGCCGCTGGGGTCCCTTTT
GCCTCAGATACTATTTTGAAGCAAGCCCCGCCCAACACGGACTGGCGTTTCTCTCAGGCC
CAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGGCCCAACAAC
CAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAAGCTGCTGAT
GGGAGCTCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGCTACGGACCC
CAGTTCACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTACATCCCAGGCAGCAAT
GCCACACTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCAGGTGGCAATGGC
AACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 931 |
| Molecular Weight
| 100874.1 |
| Theoretical pI
| 4.66 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin gamma-B2
MKASSGRCGLVRWLQVLLPFLLSLFPGALPVQIRYSIPEELAKNSVVGNLAKDLGLSVRD
LPARKLRVSAEKEYFTVNPESGDLLVSDRIDREQICGKQPLCVLDFDTVAENPLNIFYIA
VIVQDINDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYFDL
AEKQTPDGRKYPELILKHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDNPP
VFSQDVYRVTLREDVPPGFFVLQVTATDRDEGINAEITYSFHNVDEQVKHFFNLNEKTGE
ITTKDDLDFEIASSYTLSIEAKDPGDLAAHCSIQVEILDDNDCAPEVIVTSVSTPLPEDS
PPGTVIALIKTRDRDSGENGEVYCQVLGNAKFILKSSSKNYYKLVTDGALDREEIPEYNL
TITATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAENNPPGASIAQISASDPD
LGPSGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFELTLQARDQGSP
ALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGH
NAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATL
HLIFADSLQEVLPDLSDRREPSDPQAKLQFYLVVALALISVLFFLAVILAISLRLRLSSR
SDAWDCFQPGLSSKPGPGVLPNYSEGTLPYSYNLCVASQSAKTEFNFLNITPELVPAQDL
VCDNASWEQNTNHGAAGVPFASDTILKQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNN
QFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSN
ATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
|
| External Links |
|---|
| GenBank ID Protein
| 5456959 |
| UniProtKB/Swiss-Prot ID
| Q9Y5G2 |
| UniProtKB/Swiss-Prot Entry Name
| PCDGE_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152331 |
| GeneCard ID
| PCDHGB2 |
| GenAtlas ID
| PCDHGB2 |
| HGNC ID
| HGNC:8709 |
| References |
|---|
| General References
| Not Available |