| Identification |
|---|
| HMDB Protein ID
| CDBP03136 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin gamma-B1 |
| Description
| Not Available |
| Synonyms
|
- PCDH-gamma-B1
|
| Gene Name
| PCDHGB1 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| cell part |
| plasma membrane |
| membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHGB1 |
| Gene Sequence
|
>2784 bp
ATGCAGAGAGCCAGAGAAGCCGAAATGATGAAAAGTCAGGTACTGTTTCCCTTCCTGCTG
TCTTTGTTCTGCGGGGCCATCTCCCAGCAGATCCGATACACGATTCCAGAGGAGCTAGCC
AACGGCTCACGGGTGGGGAAACTTGCCAAGGATCTGGGGCTCAGTGTCCGGGAGTTGCCA
ACTCGAAAACTGCGGGTTAGTGCAGAGGATTATTTCAACGTTAGTTTGGAGAGCGGGGAT
TTGTTAGTGAACGGTAGGATAGATCGAGAGAAGATTTGCGGAAGGAAACTTGAGTGTGCA
CTAGAATTCGAAACGGTCGCTGAAAACCCAATGAATGTTTTCCACGTGGTTGTTGTAATC
CAAGATATTAATGACAATGCACCACGTTTCGTTGCAAAAGGCATTGACTTAGAAATTTGT
GAGTCAGCCTTACCCGGGGTAAAATTCTCTCTGGATTCTGCTCAAGATGCAGATGTGGAA
GGCAATTCACTGAAGTTATACACCATCAACCCCAATCAATACTTCTCTCTGTCAACGAAG
GAAAGTCCTGATGGAAGTAAATATCCGGTATTACTGCTGGAAAAACCTCTAGACAGGGAA
CATCAGAGCTCTCATCGCTTAATCCTGACTGCCATGGATGGCGGGGACCCGCCTCTAAGC
GGCACCACCCATATCTGGATCCGAGTTACGGATGCCAATGATAATGCTCCCGTGTTTAGC
CAGGAGGTATACAGGGTTAGCCTCCAAGAAAACGTACCGTGGGGAACCTCCGTGCTGCGG
GTGATGGCCACAGACCAGGATGAGGGCATTAATGCAGAGATCACCTATGCCTTCCTCAAT
TCCCCAATAAGTACCAGCCTCTTCAATCTCAATCCAAATACTGGCGACATCACAACCAAT
GGCACATTGGATTTTGAAGAGACAAGTAGATATGTGTTGAGTGTGGAAGCTAAGGATGGA
GGAGTACACACAGCTCACTGTAATGTTCAAATAGAAATTGTTGACGAGAATGACAATGCC
CCAGAGGTGACATTCATGTCCTTCTCTAACCAGATTCCAGAGGATTCAGACCTTGGAACT
GTAATAGCCCTCATAAAAGTGCGAGACAAGGATTCTGGGCAAAATGGCATGGTGACATGC
TATACTCAGGAAGAAGTTCCTTTCAAATTAGAATCCACCTCGAAGAATTATTACAAGCTG
GTGATTGCTGGAGCCCTAAACCGGGAGCAGACAGCAGACTACAACGTCACAATCATAGCC
ACCGACAAGGGCAAACCAGCCCTTTCCTCCAGGACAAGCATCACCCTGCACATCTCCGAC
ATCAACGACAATGCACCTGTTTTCCATCAGGCCTCCTATGTGGTCCACGTGTCTGAGAAC
AACCCACCTGGCGCCTCCATTGCACAAGTAAGCGCCTCCGACCCGGATTTGGGACCCAAC
GGCAGAGTCTCCTACTCTATTCTGGCCAGTGACCTGGAGCCGCGGGAGCTGTTGTCCTAC
GTGTCCGTGAGCCCGCAGAGCGGGGTGGTGTTCGCGCAGCGCGCCTTCGACCACGAGCAG
CTGCGCGCCTTCGAGCTCACACTGCAGGCCAGGGACCAGGGCTCCCCCGCGCTCAGCGCC
AACGTGAGCCTGCGCGTGTTGGTGGGCGACCTCAATGACAATGCGCCACGGGTGCTGTAC
CCCGCGCTGGGGCCTGATGGCTCCGCCCTCTTCGATATGGTGCCACGCGCCGCAGAGCCC
GGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGCAGACTCAGGACACAACGCTTGGCTG
TCCTACCACGTGCTGCAGGCCAGCGAGCCCGGGCTCTTCAGCCTGGGGTTGCGCACGGGT
GAGGTGCGCACAGCGCGTGCCTTGGGCGACAGGGACGCGGCCCGCCAGCGCCTGCTGGTC
GCTGTGCGTGATGGAGGACAGCCGCCACTCTCCGCCACCGCCACGCTGCACCTAATCTTC
GCGGATAGCCTGCAAGAGGTATTGCCAGACCTCAGCGACCGCCCTGAGCCCTCTGACCCC
CAGACGGAACTGCAGTTTTACCTGGTTGTGGCCTTGGCCTTGATCTCAGTGCTCTTTCTC
CTCGCGGTGATTCTAGCGATCGCCCTGCGCCTGCGACGTTCCTCCAGCCTCGACACTGAG
GGCTGCTTTCAAACCGGTCTCTGCTCCAAGTCTGGGCCCGGGGTTCCTCCCAACCACAGC
GAGGGGACTTTGCCCTATTCCTACAATCTATGTATTGCCTCTCATTCTGCAAAGACAGAG
TTTAATTCTCTCAACCTGACACCGGAAATGGCTCCCCCTCAGGATCTGCTGTGTGATGAT
CCTTCTATGGTTGTATGTGCCAGTAATGAAGATCACAAAATCGCTTATGACCCTTCTTTG
TCTTCGCACCAAGCCCCGCCCAACACGGACTGGCGTTTCTCTCAGGCCCAGAGACCCGGC
ACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGGCCCAACAACCAGTTTGACACA
GAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAAGCTGCTGATGGGAGCTCCACC
CTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGCTACGGACCCCAGTTCACCCTG
CAGCACGTGCCCGACTACCGCCAGAATGTCTACATCCCAGGCAGCAATGCCACACTGACC
AACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCAGGTGGCAATGGCAACAAGAAGAAG
TCGGGCAAGAAGGAGAAGAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 927 |
| Molecular Weight
| 100358.5 |
| Theoretical pI
| 4.69 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin gamma-B1
MQRAREAEMMKSQVLFPFLLSLFCGAISQQIRYTIPEELANGSRVGKLAKDLGLSVRELP
TRKLRVSAEDYFNVSLESGDLLVNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVI
QDINDNAPRFVAKGIDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTK
ESPDGSKYPVLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFS
QEVYRVSLQENVPWGTSVLRVMATDQDEGINAEITYAFLNSPISTSLFNLNPNTGDITTN
GTLDFEETSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAPEVTFMSFSNQIPEDSDLGT
VIALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIA
TDKGKPALSSRTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPN
GRVSYSILASDLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSA
NVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWL
SYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIF
ADSLQEVLPDLSDRPEPSDPQTELQFYLVVALALISVLFLLAVILAIALRLRRSSSLDTE
GCFQTGLCSKSGPGVPPNHSEGTLPYSYNLCIASHSAKTEFNSLNLTPEMAPPQDLLCDD
PSMVVCASNEDHKIAYDPSLSSHQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDT
EMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLT
NAAGKRDGKAPAGGNGNKKKSGKKEKK
|
| External Links |
|---|
| GenBank ID Protein
| 5456957 |
| UniProtKB/Swiss-Prot ID
| Q9Y5G3 |
| UniProtKB/Swiss-Prot Entry Name
| PCDGD_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152330 |
| GeneCard ID
| PCDHGB1 |
| GenAtlas ID
| PCDHGB1 |
| HGNC ID
| HGNC:8708 |
| References |
|---|
| General References
| Not Available |