| Identification |
| HMDB Protein ID
| CDBP03134 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin gamma-A11 |
| Description
| Not Available |
| Synonyms
|
- PCDH-gamma-A11
|
| Gene Name
| PCDHGA11 |
| Protein Type
| Metal Binding |
| Biological Properties |
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHGA11 |
| Gene Sequence
|
>2808 bp
ATGGCGAATCGGCTACAGCGCGGGGACCGCAGTCGGCTGCTGCTGCTGCTGTGCATTTTC
CTGGGGACGCTGCGGGGGTTCCGGGCCAGGCAGATCCGATATTCGGTGCCAGAAGAGACC
GAAAAGGGCTCCTTCGTGGGCAATATCTCCAAGGACCTGGGGCTGGAGCCCCGGGAGCTG
GCGAAGCGCGGAGTCCGCATCGTCTCCAGAGGGAAGACACAGCTTTTCGCTGTGAATCCG
CGAAGCGGCAGCTTGATCACGGCAGGCAGGATAGACCGGGAGGAGCTCTGTGAGACGGTG
TCCTCCTGTTTTTTAAATATGGAACTTCTCGTGGAAGACACCTTGAAGATTTACGGAGTG
GAGGTGGAAATAATAGATATTAATGATAACGCCCCCAGCTTCCAGGAGGACGAAGTGGAG
ATAAAAGTCAGTGAGCACGCAATTCCTGGGGCGCGATTTGCTCTTCCTAATGCTAGGGAT
CCAGATGTGGGCGTGAACTCCCTCCAGAGCTACCAGCTCAGCCCTAATAATTACTTTTCC
TTGCAACTGCGGGGCAGAACGGATGGGGCCAAGAATCCAGAGCTAGTACTGGAGGGAAGC
CTGGACCGAGAGAAAGAGGCTGCTCACCTGCTCCTCCTCACAGCTTTAGATGGAGGCGAT
CCCATCCGAAAGGGCGCAGTTCCCATTCGTGTGGTGGTCCTCGATGTAAATGATCACATC
CCAATGTTTACACAGTCCGTATATCGCGTGAGTGTTCCAGAAAACATCAGCTCCGGAACT
CGGGTGCTGATGGTTAATGCAACGGATCCAGACGAGGGAATCAACGGGGAAGTAATGTAT
TCATTTCGGAACATGGAAAGCAAGGCTTCTGAAATATTCCAATTGGATTCACAAACTGGA
GAAGTTCAAGTACGGGGGTCTCTGGATTTTGAAAAATATAGATTCTATGAGATGGAAATT
CAAGGCCAAGATGGTGGAGGTCTCTTTACCACCACGACGATGTTGATCACTGTTGTGGAT
GTGAATGATAACGCTCCAGAAATAACTATCACCTCTTCTATTAATTCAATTCTGGAAAAC
TCTCCTCCAGGTACAGTGATTGCTCTTCTAAATGTGCAAGATCAAGATTCTGGAGAAAAT
GGTCAAGTCTCCTGTTTTATTCCTAACCACCTGCCTTTTAAATTAGAAAAGACTTATGGA
AATTATTACAAATTGATAACAAGCAGAGTGCTGGACAGGGAGTTGGTCCAGAGCTACAAT
ATAACGTTGACAGCCACAGACCAGGGAAGCCCGCCTTTGTCTGCAGAAACTCATGTCTGG
CTGAATGTGGCAGATGACAACGATAACCCTCCCGTTTTTCCTCACTCCTCTTACTCTGCC
TACATTCCCGAAAACAACCCCAGGGGTGCCTCCATCTTCTCAGTGACCGCCCTCGACCCG
GACAGCAAACAGAATGCCCTGGTCACTTACTCTCTGACGGATGACACTGTCCAGGGGGTG
CCTCTGTCCTCCTATGTCTCTATTAACTCCAACACTGGTGTTCTCTATGCCCTACAATCC
TTCGACTATGAGCAGTTTCGAGACTTAGAACTGAGAGTGATAGCACGTGACAGCGGGGAC
CCGCCCCTCAGCAGCAACGTGTCGCTGAGCCTGTTCGTGCTGGACCAGAACGACAATGCG
CCCGAGATCCTGTACCCTGCCCTCCCCACAGACGGCTCCACTGGCGTGGAGCTGGCGCCC
CGCTCTGCGGAACCTGGCTACCTGGTGACCAAGGTGGTTGCGGTGGACAAAGATTCAGGC
CAGAACGCCTGGCTGTCCTATCGCCTGCTTAAGGCCAGCGAGCCGGGACTCTTCGCGGTG
GGGGAGCACACGGGCGAGGTGCGTACAGCGCGGGCACTGCTGGACAGAGACGCGCTCAAG
CAGAGCCTCGTGGTGGCCGTCCAGGACCACGGCCAGCCCCCTCTCTCGGCCACCGTCACG
CTCACCGTGGCTGTGGCCGACAGCATCCCCGAAGTCCTGGCGGACCTCGGCAGCCTCGAG
TCTCTGGCTAACTCTGAAACCTCAGACCTCTCGCTGTACTTGGTGGTGGCGGTGGCCGCA
GTCTCCTGCATCTTCCTGGTCTTTGTCATCGTGCTGCTGGCACTCAGGCTGTGGCGCTGG
CATAAGTCACGCCTGCTGCAGGCTTCTGAAGGCGGGTTGGCAGGTATGCCCACGTCACAT
TTTGTAGGCGTGGACGGGGTACAGGCTTTCCTGCAAACCTATTCCCACGAGGTCTCTCTC
ATTGCGGACTCGCAGAAGAGTCACCTGATTTTCCCCCAGCCCAACTATGGGGACACGCTC
ATCAGCCAGGAGAGCTGTGAGAAAAGCGAGCCACTCTTGATAGCTGAAGACTCAGCTATC
ATTTTAGGCAAATGTGACCCGACAAGTAATCAGCAAGCCCCGCCCAACACGGACTGGCGT
TTCTCTCAGGCCCAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACC
TGGCCCAACAACCAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGT
GAAGCTGCTGATGGGAGCTCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCC
CGCTACGGACCCCAGTTCACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTACATC
CCAGGCAGCAATGCCACACTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCA
GGTGGCAATGGCAACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
|
| Protein Properties |
| Number of Residues
| 935 |
| Molecular Weight
| 101542.0 |
| Theoretical pI
| 4.56 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin gamma-A11
MANRLQRGDRSRLLLLLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPREL
AKRGVRIVSRGKTQLFAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGV
EVEIIDINDNAPSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFS
LQLRGRTDGAKNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHI
PMFTQSVYRVSVPENISSGTRVLMVNATDPDEGINGEVMYSFRNMESKASEIFQLDSQTG
EVQVRGSLDFEKYRFYEMEIQGQDGGGLFTTTTMLITVVDVNDNAPEITITSSINSILEN
SPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYN
ITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDP
DSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGD
PPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSG
QNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVT
LTVAVADSIPEVLADLGSLESLANSETSDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRW
HKSRLLQASEGGLAGMPTSHFVGVDGVQAFLQTYSHEVSLIADSQKSHLIFPQPNYGDTL
ISQESCEKSEPLLIAEDSAIILGKCDPTSNQQAPPNTDWRFSQAQRPGTSGSQNGDDTGT
WPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYI
PGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
|
| External Links |
| GenBank ID Protein
| 5456928 |
| UniProtKB/Swiss-Prot ID
| Q9Y5H2 |
| UniProtKB/Swiss-Prot Entry Name
| PCDGB_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152320 |
| GeneCard ID
| PCDHGA11 |
| GenAtlas ID
| PCDHGA11 |
| HGNC ID
| HGNC:8698 |
| References |
| General References
| Not Available |