| Identification |
|---|
| HMDB Protein ID
| CDBP03131 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin gamma-A8 |
| Description
| Not Available |
| Synonyms
|
- PCDH-gamma-A8
|
| Gene Name
| PCDHGA8 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| metal ion binding |
| binding |
| calcium ion binding |
| ion binding |
| cation binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHGA8 |
| Gene Sequence
|
>2799 bp
ATGGCCGCTCCACAGAGTCGCCCCAGACGCGGCGAGCTGATCCTGCTGTGCGCGCTGCTG
GGAACGCTGTGGGAAATCGGGAGGGGACAGATTCGCTACTCTGTGCCAGAAGAGACGGAC
AAAGGCTCCTTCGTGGGTAATATCTCCAAGGACCTGGGGCTGGACCCCCGGAAGCTGGCG
AAGCACGGAGTCCGTATCGTCTCCAGAGGTAGGACGCAGCTCTTTGCTCTGAACCCGCGC
AGCGGCAGCTTGATCACCGCGGGCAGGATAGATCGGGAGGAGCTCTGCGCTCAGAGCCCG
CGGTGTCTGATAAATATTAACACCCTGGTTGAGGATAAAGGAAAACTCTTTGGGGTAGAA
ATAGAAATAATTGATATTAACGATAATAACCCAAAATTCCAGGTCGAAGATCTAGAAGTA
AAAATTAACGAAATCGCGGTTCCTGGAGCACGTTATCCACTCCCAGAAGCTGTTGACCCG
GATGTGGGCGTGAACTCCCTCCAGAGCTACCAGCTCAGCCCCAATCACCACTTCTCCCTG
GACGTGCAGACTGGAGACAATGGAGCCATAAACCCAGAGCTGGTGCTGGAGCGCGCCCTG
GACAGGGAGGAAGAGGCTGCTCACCACCTGGTCCTCACGGCCTCGGATGGCGGCAAGCCG
CCTCGCTCTAGCACAGTGCGCATCCACGTGACAGTGTTGGATACAAATGACAATGCCCCG
GTTTTTCCTCACCCGATTTACCGAGTGAAAGTCCTTGAGAACATGCCCCCAGGCACGCGG
CTGCTTACTGTAACAGCCAGCGACCCGGATGAGGGAATCAACGGAAAAGTGGCATACAAA
TTCCGGAAAATTAATGAAAAACAAACTCCGTTATTCCAGCTTAATGAAAATACTGGGGAA
ATATCAATAGCAAAAAGTCTAGATTATGAAGAATGTTCATTTTATGAAATGGAAATACAA
GCCGAAGATGTGGGGGCACTTCTGGGGAGGACCAAATTGCTCATTTCGGTGGAAGATGTA
AATGACAATAGACCAGAAGTGATCATTACGTCTTTGTTTAGCCCAGTGTTAGAAAATTCT
CTTCCCGGGACAGTAATTGCCTTCTTGAGTGTGCATGACCAAGACTCTGGAAAGAATGGT
CAAGTTGTCTGTTACACACGTGATAATTTACCTTTTAAATTAGAAAAGTCAATAGGTAAT
TATTATAGATTAGTGACAAGGAAATATTTGGACCGAGAAAATGTCTCTATCTACAATATC
ACAGTGATGGCCTCAGATCTAGGAACACCACCTCTGTCCACTGAAACTCAAATCGCTCTG
CACGTGGCAGACATTAACGACAACCCTCCTACTTTCCCTCATGCCTCCTACTCAGCGTAT
ATCCTAGAGAACAACCTGAGAGGAGCCTCCATCTTTTCCTTGACTGCACACGACCCCGAC
AGCCAGGAGAATGCCCAGGTCACTTACTCTGTGACCGAGGACACGCTGCAGGGGGCGCCC
CTGTCCTCGTATATCTCCATCAACTCTGACACCGGTGTCCTGTATGCGCTGCAATCTTTC
GACTATGAGCAGATCCGAGACCTGCAGCTACTGGTAACAGCCAGCGACAGCGGGGACCCG
CCCCTCAGCAGCAACATGTCACTGAGCCTGTTCGTGCTGGACCAGAATGACAACGCGCCC
GAGATCCTGTACCCCGCCCTCCCCACAGACGGTTCCACTGGCGTGGAGCTGGCGCCCCGC
TCCGCAGAGCGTGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACAGAGACTCGGGCCAG
AACGCCTGGCTGTCCTACCGCCTGCTCAAGGCCAGCGAGCCGGGACTCTTCTCGGTGGGT
CTGCACACGGGCGAGGTGCGCACGGCGCGAGCCCTGCTGGACAGAGATGCGCTCAAGCAG
AGCCTCGTGGTGGCCGTCCAGGACCATGGCCAGCCCCCTCTCTCCGCCACTGTCACGCTC
ACCGTAGCCGTGGCTGACAGCATCCCCGAAGTCCTGACCGAGTTGGGCAGTCTGAAGCCT
TCGGTCGACCCGAACGATTCGAGCCTTACACTCTATCTCGTGGTGGCAGTGGCTGCCATC
TCCTGTGTCTTCCTCGCCTTTGTCGCTGTGCTTCTGGGGCTCAGGCTGAGGCGCTGGCAC
AAGTCACGCCTGCTCCAGGATTCCGGTGGCAGATTGGTAGGCGTGCCTGCCTCACATTTT
GTGGGTGTTGAGGAGGTACAGGCTTTCCTGCAGACCTATTCCCAGGAAGTCTCCCTCACC
GCCGACTCGCGGAAGAGTCACCTGATCTTTCCCCAGCCCAACTACGCAGACATGCTCATC
AGTCAGGAGGGCTGTGAGAAAAATGATTCTTTGTTAACATCCGTAGATTTTCATGAATAT
AAGAATGAAGCTGATCATGGTCAGCAAGCCCCGCCCAACACGGACTGGCGTTTCTCTCAG
GCCCAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGGCCCAAC
AACCAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAAGCTGCT
GATGGGAGCTCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGCTACGGA
CCCCAGTTCACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTACATCCCAGGCAGC
AATGCCACACTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCAGGTGGCAAT
GGCAACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 932 |
| Molecular Weight
| 101479.0 |
| Theoretical pI
| 4.89 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin gamma-A8
MAAPQSRPRRGELILLCALLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKLA
KHGVRIVSRGRTQLFALNPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVE
IEIIDINDNNPKFQVEDLEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSL
DVQTGDNGAINPELVLERALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAP
VFPHPIYRVKVLENMPPGTRLLTVTASDPDEGINGKVAYKFRKINEKQTPLFQLNENTGE
ISIAKSLDYEECSFYEMEIQAEDVGALLGRTKLLISVEDVNDNRPEVIITSLFSPVLENS
LPGTVIAFLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNI
TVMASDLGTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPD
SQENAQVTYSVTEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDP
PLSSNMSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQ
NAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTL
TVAVADSIPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRWH
KSRLLQDSGGRLVGVPASHFVGVEEVQAFLQTYSQEVSLTADSRKSHLIFPQPNYADMLI
SQEGCEKNDSLLTSVDFHEYKNEADHGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN
NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS
NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
|
| External Links |
|---|
| GenBank ID Protein
| 14270484 |
| UniProtKB/Swiss-Prot ID
| Q9Y5G5 |
| UniProtKB/Swiss-Prot Entry Name
| PCDG8_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_032088.1 |
| GeneCard ID
| PCDHGA8 |
| GenAtlas ID
| PCDHGA8 |
| HGNC ID
| HGNC:8706 |
| References |
|---|
| General References
| Not Available |