| Identification |
|---|
| HMDB Protein ID
| CDBP03128 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin gamma-A5 |
| Description
| Not Available |
| Synonyms
|
- PCDH-gamma-A5
|
| Gene Name
| PCDHGA5 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHGA5 |
| Gene Sequence
|
>2796 bp
ATGGCGAGTCCACCTAGGGGCTGGGGCTGCGGAGAGCTGCTGCTGCCCTTCATGCTCCTG
GGGACGCTGTGCGAGCCAGGATCCGGGCAGATCCGCTACTCGATGCCGGAGGAGCTGGAC
AAAGGCTCCTTCGTCGGCAACATAGCCAAGGACCTTGGGCTGGAGCCCCAGGAGCTGGCG
GAGCGCGGAGTCCGCATCGTCTCCAGAGGTAGGACGCAGCTTTTTGCCCTGAACCCGCGA
AGCGGCAGCTTGGTCACCGCGGGCAGGATAGACCGGGAGGAGCTCTGCGCTCAGAGCCCA
CTGTGTGTGGTGAACTTTAACATCTTGGTTGAGAACAAAATGAAAATTTATGGAGTAGAA
GTAGAAATAATCGATATTAATGATAACTTCCCGCGTTTCCGGGATGAAGAGTTAAAAGTA
AAAGTTAATGAAAATGCGGCTGCAGGGACACGGTTAGTGCTTCCCTTCGCGCGGGATGCG
GATGTGGGTGTGAACTCTCTCCGGAGTTACCAGCTCAGCTCCAATCTGCACTTCTCTCTG
GATGTGGTAAGCGGAACTGATGGACAAAAGTATCCGGAGCTGGTGTTGGAACAGCCCCTA
GACCGCGAGAAAGAGACTGTTCACGACCTCCTCCTCACAGCTTTAGATGGCGGAGACCCG
GTACTCTCCGGCACCACGCACATCCGTGTTACGGTCCTCGACGCAAACGACAATGCGCCC
CTGTTCACCCCATCCGAGTACAGCGTGAGTGTTCCAGAGAACATACCTGTGGGCACTCGG
CTGCTCATGCTAACCGCCACGGATCCAGATGAGGGAATAAACGGGAAATTGACCTACTCT
TTTCGCAATGAAGAAGAAAAAATTTCGGAGACTTTCCAACTTGATTCCAACCTGGGGGAA
ATCTCAACTCTACAATCACTGGACTATGAAGAATCCAGATTCTACCTCATGGAAGTGGTA
GCTCAGGATGGAGGCGCTCTTGTTGCCAGCGCTAAGGTGGTGGTCACAGTACAGGACGTG
AATGACAATGCCCCCGAAGTGATCCTCACCTCTCTGACCAGTTCGATCTCTGAAGACTGT
CTTCCCGGAACTGTAATCGCGCTGTTTAGCGTACATGATGGTGATTCTGGAGAAAATGGT
GAGATTGCATGCTCTATTCCTAGGAATTTGCCTTTTAAATTGGAGAAGTCAGTTGATAAT
TACTATCACCTATTAACAACTAGGGACCTGGACAGAGAAGAGACTTCAGATTATAATATC
ACTTTAACCGTCATGGACCATGGAACCCCGCCCCTCTCTACAGAAAGCCACATCCCCTTG
AAAGTAGCAGACGTTAATGACAACCCACCCAATTTCCCTCAAGCCTCCTACTCCACCTCT
GTCACAGAAAACAATCCCAGAGGTGTCTCTATCTTCTCTGTGACAGCCCATGACCCCGAC
AGCGGCGACAACGCTCGAGTCACCTACTCCCTGGCTGAAGACACATTTCAGGGGGCGCCC
TTGTCCTCCTATGTATCCATTAACTCTGACACCGGTGTCCTGTATGCTCTGAGATCCTTC
GACTATGAGCAGTTGAGAGACCTACAGTTGTGGGTGACAGCCAGCGACAGTGGGAACCCT
CCACTTAGCAGCAACGTGTCGCTGAGCCTGTTTGTGCTGGACCAGAACGACAATACGCCT
GAGATCCTGTACCCCGCCCTCCCCACAGACGGTTCCACGGGCGTGGAGCTGGCGCCTCGC
TCCGCAGAACCTGGCTACCTGGTGACCAAGGTGGTAGCGGTGGACAAAGATTCAGGCCAG
AACGCCTGGCTGTCCTACCGCCTGCTTAAGGCCAGCGAGCCAGGACTCTTTGCGGTTGGG
CTGCACACGGGCGAGGTGCGCACAGCGCGAGCCCTGCTGGACAGAGACGCGCTCAAGCAG
AGCCTCGTGGTGGCCGTCGAAGACCATGGCCAGCCCCCTCTGTCAGCCACCTTCACGGTC
ACCGTTGCCGTGGCCGACAGGATCCCTGACATCCTGGCTGACCTAGGCAGTATCAAGACC
CCCATTGACCCTGAGGATCTGGACCTCACACTCTATCTTGTGGTGGCAGTGGCTGCAGTC
TCCTGCGTCTTCCTGGCCTTCGTCATCGTGCTGCTGGTGCTCAGACTGAGGCGCTGGCAC
AAGTCACGCCTGCTTCAGGCTGAAGGCAGCAGGTTGGCGGGTGTGCCCGCCTCGCACTTT
GTGGGCGTGGATGGGGTTCGGGCTTTCCTGCAGACCTATTCCCACGAGGTCTCCCTCACC
GCGGACTCGAGGAAGAGTCACCTGATCTTTCCCCAGCCCAACTACGCAGACACGCTCCTT
AGTGAAGAGAGCTGTGAGAAAAGCGAGCCTCTTCTGATGTCTGATAAGGTAGATGCAAAC
AAAGAAGAACGGCGAGTTCAGCAAGCCCCGCCCAACACGGACTGGCGTTTCTCTCAGGCC
CAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGGCCCAACAAC
CAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAAGCTGCTGAT
GGGAGCTCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGCTACGGACCC
CAGTTCACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTACATCCCAGGCAGCAAT
GCCACACTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCAGGTGGCAATGGC
AACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 931 |
| Molecular Weight
| 100934.1 |
| Theoretical pI
| 4.47 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin gamma-A5
MASPPRGWGCGELLLPFMLLGTLCEPGSGQIRYSMPEELDKGSFVGNIAKDLGLEPQELA
ERGVRIVSRGRTQLFALNPRSGSLVTAGRIDREELCAQSPLCVVNFNILVENKMKIYGVE
VEIIDINDNFPRFRDEELKVKVNENAAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSL
DVVSGTDGQKYPELVLEQPLDREKETVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAP
LFTPSEYSVSVPENIPVGTRLLMLTATDPDEGINGKLTYSFRNEEEKISETFQLDSNLGE
ISTLQSLDYEESRFYLMEVVAQDGGALVASAKVVVTVQDVNDNAPEVILTSLTSSISEDC
LPGTVIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNI
TLTVMDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPD
SGDNARVTYSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNP
PLSSNVSLSLFVLDQNDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQ
NAWLSYRLLKASEPGLFAVGLHTGEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTV
TVAVADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRLRRWH
KSRLLQAEGSRLAGVPASHFVGVDGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTLL
SEESCEKSEPLLMSDKVDANKEERRVQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNN
QFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSN
ATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
|
| External Links |
|---|
| GenBank ID Protein
| 5456942 |
| UniProtKB/Swiss-Prot ID
| Q9Y5G8 |
| UniProtKB/Swiss-Prot Entry Name
| PCDG5_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152325 |
| GeneCard ID
| PCDHGA5 |
| GenAtlas ID
| PCDHGA5 |
| HGNC ID
| HGNC:8703 |
| References |
|---|
| General References
| Not Available |