| Identification |
|---|
| HMDB Protein ID
| CDBP03126 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin gamma-A3 |
| Description
| Not Available |
| Synonyms
|
- PCDH-gamma-A3
|
| Gene Name
| PCDHGA3 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHGA3 |
| Gene Sequence
|
>2799 bp
ATGACCAATTGCCTGAGTTTCCGAAATGGCAGAGGACTGGCCCTGCTGTGCGCGCTCCTG
GGGACGCTGTGCGAAACAGGATCCGGTCAGATCCGCTACTCGGTGTCTGAGGAGCTAGAT
AAAGGTTCCTTCGTGGGCAACATCGCTAACGACCTGGGGCTAGAGCCCCGGGAGCTGGCG
GAGCGCGGAGTCCGCATCGTCTCCAGAGGTAGGACGCAGCTTTTCTCTCTGAATCCGCAA
AGCGGCAGCTTGGTCACCGCGGAGAGGATAGACCGGGAGGAGCTCTGCGCTCAGATCCCG
CTGTGTCTGGTAAAAATTAACATTCTGGTTGAGGATAAATTGAAAATTTTTGAAGTAGAA
ATAGAAATTAAAGATATTAATGATAATGCTCCTAATTTCCCAACAGAGGAATTGGAAATA
AAAATTGGTGAACTAACGGTTCCTGGAACCCGATTTCCAATTAAAACTGCTTTTGACCCA
GATGTAGGCATTAACTCCCTGCAGAACTACAAGCTTAGCCCCAATGACTACTTCTCTCTG
GCTGTGAATAGCGTCTCTGAGGGGGCCAAGTATCCAGAGCTGGTGCTGGAGCGGGCCCTG
GACCGTGAGAAAAAAGAAATTCACCAGCTTGTCCTGGTTGCCTCTGATGGTGGCGACCCT
GTCCACTCTGGCAACTTGCACATCCAAGTGATAGTCCTGGATGCAAATGACAACCCACCA
ATGTTTACTCAGCCTGAGTACCGTGTGAGTGTTTGGGAGAACGTGCCTGTGGGTACCCGG
CTGCTCACGGTGAATGCCACTGACCCTGACGAGGGATTCAATGCTCAAGTGTCTTATATT
CTAGATAAAATGCCTGGGAAAATCGCTGAGATTTTCCATCTTAACTCAGTGAGTGGAGAA
GTATCAATATTAAAAAGTCTAGATTATGAGGATGCCATGTTCTATGAAATTAAAATTGAA
GCACAGGATGGACCAGGTCTTCTTTCAAGAGCCAAGATTCTAGTCACGGTTCTGGATGTG
AATGACAATGCTCCAGAAATTACAATCACGTCTCTCACAAGCTCAGTCCCAGAAGAGGGC
ACCGTTGGAAGAGAAATTGCTCTTATCGACGTGCATGACCGAGATTCTGGGCAGAATGGG
CAGGTTGAAGTTTTTGTCCTGGGAAATCTGCCATTTAAGTTAGAAAAATCAATAGATCAA
TATTACCGCTTAGTGACGGCCACATCCCTGGACCGCGAACAAATATCAGAATATAACATT
AGTCTGAGAGCCTCAGATGGGGGAAGCCCGCCACTGTCCACAGAAACTCACATCACCCTG
CATGTGATTGACATCAATGACAACCCACCCACCTTCCCTCATTTATCCTACTCCGCCTAC
ATTCCAGAAAACAACCCCAGAGGAGCCTCCATCTTCTCAGTGACAGCCCAGGACCCAGAT
AGCAACAACAACGCCCGCATCACTTATGCATTGACCGAGGACACTCTCCAGGGGGCGCCC
CTGTCCTCCTTCGTCTCTATCAACTCCAACACTGGCGTCCTATACGCGCTGAGATCCTTC
GACTACGAGCAATTTAGAGACTTAAAGCTACTGGTGACAGCCAGCGACAGCGGGAACCCT
CCACTCAGCAGCAACGTGTCGCTGAACCTGTTCGTGCTGGACCAGAACGACAACGCGCCC
GAGATCCTGTACCCCGCCCTCCCCACAGACGGTTCCACTGGCGTGGAGCTGGCGCCTCGC
TCCGCAGAGCCCGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACAGAGACTCGGGCCAG
AACGCCTGGCTGTCCTACCGCCTGCTCAAGGCCAGCGAGCCGGGACTCTTCTCGGTGGGT
CTGCACACGGGCGAGGTGCGCACGGCGCGAGCCCTGCTGGACAGAGACGCGCTCAAGCAG
AGCCTCGTGGTGGCCGTCCAGGACCACGGCCAGCCCCCTCTCTCCGCCACTGTCACGCTC
ACCGTGGCCGTGGCCGACAGGATCCCCGACATCCTGGCCGACCTGGGCAGCCTCGAGCCC
TCCGCCAAACCCAACGATTCGGACCTCACTCTGTACCTGGTGGTGGCGGTGGCCGCGGTC
TCCTGCGTCTTCCTGGCCTTCGTCATCGTGCTGCTGGCGCTCAGGCTGCGGCGCTGGCAC
AAGTCACGCCTGCTGCAGGCTTCGGGAGGCGGCTTGGCGAGTACGCCCGGCTCGCACTTT
GTGGGCGCGGACGGGGTTCGGGCTTTCCTGCAGACCTATTCCCACGAGGTCTCCCTCACT
GCGGACTCGCGGAAGAGCCACCTGATTTTCCCCCAGCCCAACTATGCGGACACGCTCATC
AGCCAGGAGAGCTGTGAGAAAAGCGAGCCTCTTCTGATAACTCAGGATTTACTTGAAATG
AAAGGAGATTCCAACCTACTTCAGCAAGCCCCGCCCAACACGGACTGGCGTTTCTCTCAG
GCCCAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGGCCCAAC
AACCAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAAGCTGCT
GATGGGAGCTCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGCTACGGA
CCCCAGTTCACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTACATCCCAGGCAGC
AATGCCACACTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCAGGTGGCAAT
GGCAACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 932 |
| Molecular Weight
| 100969.5 |
| Theoretical pI
| 4.61 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin gamma-A3
MTNCLSFRNGRGLALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELA
ERGVRIVSRGRTQLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVE
IEIKDINDNAPNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSL
AVNSVSEGAKYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPP
MFTQPEYRVSVWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSGE
VSILKSLDYEDAMFYEIKIEAQDGPGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEG
TVGREIALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNI
SLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPD
SNNNARITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNP
PLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQ
NAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTL
TVAVADRIPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWH
KSRLLQASGGGLASTPGSHFVGADGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTLI
SQESCEKSEPLLITQDLLEMKGDSNLLQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN
NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS
NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
|
| External Links |
|---|
| GenBank ID Protein
| 14589880 |
| UniProtKB/Swiss-Prot ID
| Q9Y5H0 |
| UniProtKB/Swiss-Prot Entry Name
| PCDG3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_018916.3 |
| GeneCard ID
| PCDHGA3 |
| GenAtlas ID
| PCDHGA3 |
| HGNC ID
| HGNC:8701 |
| References |
|---|
| General References
| Not Available |