| Identification |
|---|
| HMDB Protein ID
| CDBP03125 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin gamma-A2 |
| Description
| Not Available |
| Synonyms
|
- PCDH-gamma-A2
|
| Gene Name
| PCDHGA2 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHGA2 |
| Gene Sequence
|
>2799 bp
ATGGCGGCTCTGCAAAAGTTGCCACACTGCAGAAAGCTGGTCCTGCTGTGCTTCCTTTTG
GCGACCCTGTGGGAGGCCAGGGCCGGGCAGATTCGCTATTCTGTGCGGGAAGAGATCGAC
AGAGGCTCCTTCGTAGGCAACATCGCCAAGGACTTGGGTTTGGAGCCCCTGGCACTGGCA
GAGCAGGGAGTCCGCATCGTCTCCAGAGGTAGGTCCCAGCTCTTTGCTCTGAACCCGCGA
AGCGGCAGCTTGGTCACTGCGAACAGGATAGACCGGGAGGAGCTCTGCGCTCAGAGCGCA
CCCTGTCTGTTGAATTTTAACATTCTGCTGGAGGATAAATTGACTATTTATTCAGTAGAG
GTGGAAATAACAGATATTAACGATAATGCCCCTCGCTTTGGAGTAGAGGAACTGGAGCTA
AAAATCAGTGAAACCACTACGCCAGGATTCCGGATTCCTCTTAAGAATGCGCATGATGCA
GACGTAGGTGAGAACGCCCTTCAGAAGTACGCACTCAACCCAAATGACCACTTCTCCCTG
GACGTGCGAAGGGGAGCTGATGGGAACAAGTACCCAGAACTGGTGCTGGAGCGCTCTCTG
GACCGCGAGGAAGAGGCTGTTCACCACCTCGTTCTCGTGGCTTCTGATGGGGGTGACCCA
GTGCTATCTGGCACCTCCCGCATCTGCGTGAAGGTCCTGGATGCGAACGACAATGCGCCT
GTTTTTACACAGCCCGAGTACCGCATAAGCATTCCGGAGAATACGCTCGTGGGCACCCGG
ATACTCACGGTGACCGCCACTGACGCAGATGAGGGCTACTACGCTCAAGTGGTATATTTT
CTAGAGAAAAGCCCTGGAGAAACCTCAGAGGTATTTGAGCTTAAGTCAACATCTGGAGAA
CTGACAATCATAAAAGATCTAGATTATGAGGATGCTACATTCCATGAAATTGATATTGAA
GCTCAGGATGGTCCGGGCCTTCTAACCAGAGCGAAGGTTATCGTCACGGTTCTGGATGTG
AATGACAATGCCCCAGAATTTTACATGACATCTGCTACTAGCTCAGTTTCTGAAGACTCT
CTTCCAGGAACCATAATTGGGCTTTTTAATGTACATGATAGAGACTCTGGGCAGAACGCA
TTCACCACCTGTTCACTCCCCGAGGATCTTCCTTTTAAGTTAGAAAAGTCAGTAGACAAT
TACTACCGACTGGTTACAACCAGAGCCCTTGACAGGGAACAGTTTTCCTTTTACAACATC
ACTCTAACCGCTAAAGATGGAGGGAACCCCTCCCTGTCCACGGATGCTCACATTTTGCTC
CAGGTGGCAGACATCAACGACAACGCACCCGCCTTCTCCCGCACATCCTACTCCACCTAC
ATTCCCGAAAACAACCCCAGAGGAGCCTCTGTCTTCTCAGTGACGGCCCATGACCCCGAC
AGCAACGACAATGCTCATGTAACTTACTCTTTCGCGGAGGACACTGTTCAGGGGGCACCC
TTATCCTCTTACATCTCTATCAACTCCGACACTGGAGTACTCTATGCACTGCGCTCCTTT
GATTATGAGCAGTTGCGAGACTTGCAAGTGTGGGTGATAGCGCGGGACAGCGGGAACCCT
CCACTCAGTAGCAATGTATCATTAAGCCTGTTCGTGCTGGACCAGAACGACAACGCGCCC
GAGATCCTGTACCCTGCCTTCCCCACAGACGGTTCCACTGGCGTGGAGCTGGCGCCCCGC
TCCGCAGAGCCCGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACAGAGACTCGGGCCAG
AACGCCTGGCTGTCTTACCACCTGCTCAAGGCCAGCGAGCCGGGACTCTTCTCGGTGGGT
CTGCACACGGGCGAGGTGCGCACGGCGCGAGCCCTGCTGGACAGAGACGCGCTCAAGCAG
AGCCTCGTGGTGGCCATCCAGGACCACGGCCAGCCCCCTCTCTCCGCCACTGTCACGCTC
ACCGTGGCCGTGGCCGACAGGATCCCCGACATCCTGGCCGACCTGGGCAGCCTCGAGCCC
TCCGCCATACCCAACGATTCGGACCTCACTCTGTACCTGGTGGTGGCGGTGGCCGCGGTC
TCCTGCGTCTTCCTGGCCTTCGTCATCGTGTTGCTGGCGCACAGGCTGCGGCGCTGGCAC
AAGTCACGCCTGCTGCAGGCTTCAGGAGGCAGCTTGACAGGCATGCAGAGCTCGCACTTT
GTGGGCGTGGACGGGGTTCGGGCTTTCCTGCAGACCTATTCCCACGAGGTCTCCCTCACT
GCGGACTCGCGGAAGAGCCACCTGATTTTCCCCCAGCCCAACTATGCGGACACGCTCATC
AGCCAGGAGAGCTGTGAGAAAAAGGATTTTTTATCAGCGCCTCAATCTCTACTCGAAGAA
GAAAGAGAAGAAACGTTTTCTCAGCAAGCCCCGCCCAACACGGACTGGCGTTTCTCTCAG
GCCCAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGGCCCAAC
AACCAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAAGCTGCT
GATGGGAGCTCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGCTACGGA
CCCCAGTTCACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTACATCCCAGGCAGC
AATGCCACACTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCAGGTGGCAAT
GGCAACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 932 |
| Molecular Weight
| 101483.3 |
| Theoretical pI
| 4.61 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin gamma-A2
MAALQKLPHCRKLVLLCFLLATLWEARAGQIRYSVREEIDRGSFVGNIAKDLGLEPLALA
EQGVRIVSRGRSQLFALNPRSGSLVTANRIDREELCAQSAPCLLNFNILLEDKLTIYSVE
VEITDINDNAPRFGVEELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDHFSL
DVRRGADGNKYPELVLERSLDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAP
VFTQPEYRISIPENTLVGTRILTVTATDADEGYYAQVVYFLEKSPGETSEVFELKSTSGE
LTIIKDLDYEDATFHEIDIEAQDGPGLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDS
LPGTIIGLFNVHDRDSGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQFSFYNI
TLTAKDGGNPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPD
SNDNAHVTYSFAEDTVQGAPLSSYISINSDTGVLYALRSFDYEQLRDLQVWVIARDSGNP
PLSSNVSLSLFVLDQNDNAPEILYPAFPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQ
NAWLSYHLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAIQDHGQPPLSATVTL
TVAVADRIPDILADLGSLEPSAIPNDSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWH
KSRLLQASGGSLTGMQSSHFVGVDGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTLI
SQESCEKKDFLSAPQSLLEEEREETFSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPN
NQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGS
NATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
|
| External Links |
|---|
| GenBank ID Protein
| 5456934 |
| UniProtKB/Swiss-Prot ID
| Q9Y5H1 |
| UniProtKB/Swiss-Prot Entry Name
| PCDG2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152322 |
| GeneCard ID
| PCDHGA2 |
| GenAtlas ID
| PCDHGA2 |
| HGNC ID
| HGNC:8700 |
| References |
|---|
| General References
| Not Available |