| Identification |
|---|
| HMDB Protein ID
| CDBP03123 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin alpha-C2 |
| Description
| Not Available |
| Synonyms
|
- PCDH-alpha-C2
|
| Gene Name
| PCDHAC2 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| metal ion binding |
| binding |
| calcium ion binding |
| ion binding |
| cation binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHAC2 |
| Gene Sequence
|
>3024 bp
ATGGAGCAGGCGGGCACCAGACCTGCGGCGACAGAGCATCCACGGCTCCGGCGGCCCATG
CCCTGGCTGCTGCTACTGCCTCTCCTGCTGCTGTTGCTGCTGCTGCTACCTGGCCCAGCG
GCCTCCCAGCTGCGATACTCTGTGCCAGAGGAGCAGGCACCCGGCGCGCTCGTGGGCAAC
GTGGCTCGCGCGCTGGGGCTTGAGCTGCGGCGCTTGGGGCCGGGTTGCTTGCGCATCAAC
CATCTGGGTGCGCCCAGTCCGCGCTACCTGGAGCTGGACCTGACGAGTGGAGCGCTCTTC
GTCAACGAGCGCATTGATCGGGAGGCGCTGTGTGAGCAGCGGCCTCGCTGCCTGCTCAGC
CTGGAAGTGCTGGCGCACAACCCCGTGGCGGTGAGCGCCGTTGAGGTGGAAATATTGGAC
ATCAACGACAACTCACCGCGTTTCCCGCGGCCCAACTACCAGCTTCAGGTAAGCGAATCG
GTGGCGCCTGGAGCGCGCTTTCACATAGAGAGTGCGCAGGACCCCGACGTGGGCGCCAAC
TCAGTACAGACCTACGAGCTCAGCCCCAGCGAGCACTTCGAGCTGGACCTTAAGCCCCTG
CAGGAGAACAGTAAAGTGCTTGAGCTGGTGCTGCGTAAGGGCCTAGACCGGGAGCAGGCA
GCCTTGCACCACCTGGTTCTCACAGCCGTGGATGGGGGCATTCCAGCCCGCTCGGGTACG
GCACAGATCTCTGTGCGTGTCCTGGACACTAACGACAACTCTCCTGCCTTTGACCAGTCC
ACTTATCGCGTCCAGCTACGGGAGGACTCACCCCCAGGCACATTGGTGGTGAAGCTGAAT
GCCTCAGACCCGGATGAGGGCTCCAATGGTGAGCTCAGGTACTCCTTGAGCAGCTACACG
TCGGACCGGGAGAGGCAGCTCTTCAGCATAGATGCCAGTACCGGGGAAGTGCGAGTAATT
GGGGGGCTGGATTATGAGGAAGCCTCCTCCTACCAGATCTATGTGCAGGCGACTGACCGG
GGTCCAGTGCCCATGGCAGGTCACTGCAAGGTGCTGGTGGACATCGTGGACGTGAATGAC
AATGCCCCAGAGGTGGTGCTCACGGACCTGTATAGCCCAGTGCCTGAGAATGCTACACCC
AACACCATTGTGGCCGTTCTCAGTGTCAATGACCAAGACTCAGGCCCCAACCGGAAAGTG
AGCCTGGGTCTGGAGGCCACACTGCCTTTCCGACTGAATGGCTTTGGAAACTCCTATACA
CTGGTGGTGAGCGGCCCACTGGACCGAGAGCGGGTGGCTGTCTACAACATCACGGTGACA
GCCACAGATGGGGGAATACCGCAGCTCACATCCCTGCGTACACTGAAGGTTGAGATCTCT
GACATCAATGACAATCCACCAAGCTTCCTGGAGGACTCCTATTCCATCTACATACAGGAG
AACAATTTGCCAGGTGTGTTGCTCTGTACTGTGCAAGCCACAGACCCAGATGAAAAGGAG
AATGCAGAGGTGACCTACTCCCTTCTGGAGAGGGAGATTCAAGGGCTGCCAGTCACCTCC
TATGTCTCCATTAACAGTGCCAGTGGCAGCCTTTATGCTGTCAACTCCTTTGACTATGAG
AAGTTTCGGGAGTTCTTTGTGACTGTGGAGGCTCAGGACAAGGGGAGCCCACCACTGAGC
AGCACTGTGACTGCCAACGTATATGTGGTGGACATGAATGACCATGCCCCTCACATTCTG
TACCCTACCTCAACCAACTCGTCAGCAGCCTTCGAGATGGTGCCTCGAACTGCCCCTGCT
GGCTACCTGGTCACCAAAGTCATAGCTATGGACTCAGACTCTGGGCAAAATGCTTGGCTT
TTTTACCATCTAGCCCAGACTTCTGACCTGGACCTCTTTAAGGTAGAGCTGCACACAGGA
GAAATTAGGACTACCAGGAAGATGGGAGATGAGAGTGGTAGCACTTTCAACCTGACCGTG
GTGGTCCGAGATAATGGAGAGCCATCACTATCAGCCTCTGTGGCCATTACAGTAGCTGTG
GTGGATAGGGTTTCCAAAATCCTCCCTGACACTCAGAGGCATGTTAAGAGCCCTCGGACA
TACTCTGAAATTACCCTTTATCTAATAATAGCATTAAGCACAGTGTCTTTTATATTTCTT
TTGACAATCATCATTTTGAGCATCATCAAGTGCTACCGCTACACTGCGTATGGCACTGCA
TGCTGTGGAGGCTTCTGTGGAGTAAGGGAAAGGTCCCCTGCAGAACTGTACAAACAAGCC
AACAACAATATTGATGCCAGGATACCGCATGGCCTCAAAGTGCAGCCTCACTTCATTGAA
GTTCGAGGGAATGGCTCCCTCACCAAGACCTACTGCTACAAGGCCTGTCTGACAGCAGGC
TCAGGGAGTGACACTTTCATGTTTTACAATACAGGGGCCCAGACAGGACCAGGGCCTTCG
GGAGCCCAAGCAGCAGTGACTGACAGCAGGAATCTCACAGGCCAAAGTGGTCAGAATGCT
GGGAACCTGATTATTCTCAAAAATGAGGCTGTTTCTCAAAATGAGCCACGACAGCCCAAC
CCTGACTGGCGTTACTCTGCCTCCCTGAGAGCAGGCATGCACAGCTCTGTGCACCTAGAG
GAGGCTGGCATTCTACGGGCTGGTCCAGGAGGGCCTGATCAGCAGTGGCCAACAGTATCC
AGTGCAACACCAGAACCAGAGGCAGGAGAAGTGTCCCCTCCAGTCGGTGCGGGTGTCAAC
AGCAACAGCTGGACCTTTAAATACGGACCAGGCAACCCCAAACAATCCGGTCCCGGTGAG
TTGCCCGACAAATTCATTATCCCAGGATCTCCTGCAATCATCTCCATCCGGCAGGAGCCT
ACTAACAGCCAAATTGACAAAAGTGACTTCATAACCTTCGGCAAAAAGGAGGAGACCAAG
AAAAAGAAGAAAAAGAAGAAGGGTAACAAGACCCAGGAGAAAAAAGAGAAAGGGAACAGC
ACGACTGACAACAGTGACCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 1007 |
| Molecular Weight
| 109449.0 |
| Theoretical pI
| 5.07 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin alpha-C2
MEQAGTRPAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGN
VARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLS
LEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGAN
SVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT
AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYT
SDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVND
NAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYT
LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQE
NNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE
KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPA
GYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTV
VVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFL
LTIIILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIE
VRGNGSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNA
GNLIILKNEAVSQNEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS
SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP
TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
|
| External Links |
|---|
| GenBank ID Protein
| 5456894 |
| UniProtKB/Swiss-Prot ID
| Q9Y5I4 |
| UniProtKB/Swiss-Prot Entry Name
| PCDC2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152304 |
| GeneCard ID
| PCDHAC2 |
| GenAtlas ID
| PCDHAC2 |
| HGNC ID
| HGNC:8677 |
| References |
|---|
| General References
| Not Available |