| Identification |
|---|
| HMDB Protein ID
| CDBP03115 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin beta-11 |
| Description
| Not Available |
| Synonyms
|
- PCDH-beta-11
|
| Gene Name
| PCDHB11 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| plasma membrane |
| membrane |
| cell part |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHB11 |
| Gene Sequence
|
>2394 bp
ATGGAGAACCAAGGGACACGCACTCAGCAGATAAGGCAAGTCCTGCTTCTCTTTGTTTTG
CTCGGAATGTCTCAGGCGGGCTCTGAAACCTGGAGCTTTTCTGTGGCAGAAGAAATGCAG
AGCGGGAGTTTTGTAGGCAATCTGGCAAAGGACCTGGGGCTGAAGGTGAGAGAACTGTCC
TCACGGGGGGCTCGGGTGGTCTCTAATGATAAGAAACAGCGTTTGCAGCTGGACATAAAC
ACTGGGGATTTGCTCTTAAGTGAAACACTAGACAGGGAGGAGCTCTGCGGTTCCATCGAG
CCTTGCGTGCTACATTTGCAGGTGTTAATGCAAAACCCCACGCAGTTTTTACAAATTGAG
CTTCAGGTCAGGGATATAAATGATCACTCTCCCATCTTCTCGGAAAAACAAATGCTCCTA
GAAATCCCAGAGAACAGTCCCGTTGGTGCTGTGTTCTTACTAGAAAGTGCGAAGGATTTA
GATGTAGGAATCAATGCTGTAAAAAGCTACACAATAAGCCCCAACTCTCATTTTCACATT
AAAATGAGAGTCATTCCAGACAATAGGAAATACCCCGAGTTAGTTCTGGACAAGGCGCTG
GATTATGAAGAGCTCCCGGAGCTCAGTTTCATCCTCTCTGCTCTGGATGGTGGGTCCCCT
CCCAGGTCTGGAACTGCCTTGGTCAGGGTGGTGGTTGTGGACATTAATGACAACTCCCCT
GAATTTGAGCAGGCTTTTTATGAGGTGAAGATTCGGGAGAATAGCATCCTTGGCTCGCTG
ATTTTGATTGTCTCAGCTTGGGATTTAGACTCTGGAACAAATGGTGAAATATGCTATACC
TTTTCCCATGCCTCAGAAGATATTCGCAAGACATTTGAAATTAATCAAAAGTCTGGAGAA
ATTACTTTAAGAGCACCTCTGGATTTTGAAACGATTGAGTCATACTCAATAATCATTCAA
GCCACAGATGGGGGAGGACTTTTTGGAAAATCTACAGTCATAATTCACGTGATAGATGTA
AATGACAATGCTCCTGAAATCACTGTGTCATCAATTACCAGTCCAATCCCAGAAAATACG
CCAGAGACCGTGGTTATGGTTTTTAGTATCCAAGATATAGACTCTGGGGACAACGGAAGA
ATTGTTTGTTCCATTCCGGAAGACCTCCCATTCGTGCTAAAATCTTCAGTTGAGAATTAC
TACACGTTGGAAACAGAGAGACCACTGGACAGAGAGAGCACAGCCGAGTACAATATCACC
ATCACCGTCACCGACTTGGGGATACCCAGGCTGAAAACCGAGCACAACACAACTGTGTTG
GTCTCTGACGTCAATGACAACGCCCCCACCTTCACCCAAACCTCCTACACCCTGTTCGTC
CGCGAGAACAACAGCCCCGCCCTGCACATCGGCAGTGTCAGCGCTACAGACAGAGACTCA
GGCACCAACGCCCAGGTCAACTACTCGCTACTCCCGCCCCAGGACCTGCACCTGCCCCTC
GCCTCCCTGGTCTCCATCAACACAGACAACGGCCACCTGTTCGCCCTCAGGTCGCTGGAC
TACGAGGCCCTGCAGGCTTTCGACTTCCGCGTGGGCGCCACAGACCGCGGCTCCCCGGCT
TTGAGCAGCGAGGCGCTGGTGCGCGTGCTGGTGCTGGACGCCAACGACAACTCGCCCTTC
GTGCTGTACCCGCTGCAGAACGGCTCCGCGCCCTGCACCGAGCTGGTGCCCCGGGCGGCC
GAGCCGGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGGCGACTCGGGCCAGAACGCC
TGGCTGTCGTACCAGCTGCTCAAGGCCACGGAGCCCGGGCTATTCGGCGTGTGGGCGCAC
AATGGCGAGGTGCGCACCGCCAGGCTGCTGAGCGAGCGCGACGCGGCCAAGCACAGGCTG
GTGGTGCTGGTCAAGGACAATGGCGAGCCTCCGCGCTCGGCCACCGCCACGCTGCAAGTG
CTCCTGGTGGACGGCTTCTCCCAGCCCTACCTGCCGCTCCCTGAGGCGGCACCGGCCCAG
GCCCAGGCCGACTCGCTCACCGTCTACTTGGTGGTGGCGTTGGCCTCGGTGTCTTCGCTC
TTCCTCTTCTCGGTGCTCCTGTTCGTGGCGGTGCGGCTGTGCAGGAGGAGCAGGGCGGCC
TCGGTGGGAAGCTGCTCGGTGCCTAAGGGCCCCTTTCCAGGGCATCTGGTGGACGTGAGC
GGCACCGGGACCCTTTCCCAGAGCTACCAGTACGAGGTGTGTCTGACGGGAGGTTCCGAG
ACAAATGAATTCAAGTTCCTAAAACCGGTTATCCCTAATATCCAGGCAAAAGGTCTTGGG
AAGAATAGTGAAGAAAACTCCACCTTTCGAAATAGCTTTGGATTTAATTTTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 797 |
| Molecular Weight
| 87087.5 |
| Theoretical pI
| 4.48 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin beta-11
MENQGTRTQQIRQVLLLFVLLGMSQAGSETWSFSVAEEMQSGSFVGNLAKDLGLKVRELS
SRGARVVSNDKKQRLQLDINTGDLLLSETLDREELCGSIEPCVLHLQVLMQNPTQFLQIE
LQVRDINDHSPIFSEKQMLLEIPENSPVGAVFLLESAKDLDVGINAVKSYTISPNSHFHI
KMRVIPDNRKYPELVLDKALDYEELPELSFILSALDGGSPPRSGTALVRVVVVDINDNSP
EFEQAFYEVKIRENSILGSLILIVSAWDLDSGTNGEICYTFSHASEDIRKTFEINQKSGE
ITLRAPLDFETIESYSIIIQATDGGGLFGKSTVIIHVIDVNDNAPEITVSSITSPIPENT
PETVVMVFSIQDIDSGDNGRIVCSIPEDLPFVLKSSVENYYTLETERPLDRESTAEYNIT
ITVTDLGIPRLKTEHNTTVLVSDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSATDRDS
GTNAQVNYSLLPPQDLHLPLASLVSINTDNGHLFALRSLDYEALQAFDFRVGATDRGSPA
LSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNA
WLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLQV
LLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAA
SVGSCSVPKGPFPGHLVDVSGTGTLSQSYQYEVCLTGGSETNEFKFLKPVIPNIQAKGLG
KNSEENSTFRNSFGFNF
|
| External Links |
|---|
| GenBank ID Protein
| 5457029 |
| UniProtKB/Swiss-Prot ID
| Q9Y5F2 |
| UniProtKB/Swiss-Prot Entry Name
| PCDBB_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152490 |
| GeneCard ID
| PCDHB11 |
| GenAtlas ID
| PCDHB11 |
| HGNC ID
| HGNC:8682 |
| References |
|---|
| General References
| Not Available |