| Identification |
|---|
| HMDB Protein ID
| CDBP03114 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin beta-10 |
| Description
| Not Available |
| Synonyms
|
- PCDH-beta-10
|
| Gene Name
| PCDHB10 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHB10 |
| Gene Sequence
|
>2403 bp
ATGGCTGTCAGAGAGTTGTGCTTCCCAAGACAAAGGCAAGTCCTGTTTCTTTTTCTTTTT
TGGGGAGTGTCCTTGGCAGGTTCTGGGTTTGGACGTTATTCGGTGACTGAGGAAACAGAG
AAAGGATCCTTTGTGGTCAATCTGGCAAAGGATCTGGGACTAGCAGAGGGGGAGCTGGCT
GCAAGGGGAACCAGGGTGGTTTCCGATGATAACAAACAATACCTGCTCCTGGATTCACAT
ACCGGGAATTTGCTCACAAATGAGAAACTGGACCGAGAGAAGCTGTGTGGCCCTAAAGAG
CCCTGTATGCTGTATTTCCAAATTTTAATGGATGATCCCTTTCAGATTTACCGGGCTGAG
CTGAGAGTCAGGGATATAAATGATCACGCGCCAGTATTTCAGGACAAAGAAACAGTCTTA
AAAATATCAGAAAATACAGCTGAAGGGACAGCATTTAGACTAGAAAGAGCACAGGATCCA
GATGGAGGACTTAACGGTATCCAAAACTACACGATCAGCCCCAACTCTTTTTTCCATATT
AACATTAGTGGCGGTGATGAAGGCATGATATATCCAGAGCTAGTGTTGGACAAAGCACTG
GATCGGGAGGAGCAGGGAGAGCTCAGCTTAACCCTCACAGCGCTGGATGGTGGGTCTCCA
TCCAGGTCTGGGACCTCTACTGTACGCATCGTTGTCTTGGACGTCAATGACAATGCCCCA
CAGTTTGCCCAGGCTCTGTATGAGACCCAGGCTCCAGAAAACAGCCCCATTGGGTTCCTT
ATTGTTAAGGTATGGGCAGAAGATGTAGACTCTGGAGTCAACGCGGAAGTATCCTATTCA
TTTTTTGATGCCTCAGAAAATATTCGAACAACCTTTCAAATCAATCCTTTTTCTGGGGAA
ATCTTTCTCAGAGAATTGCTTGATTATGAGTTAGTAAATTCTTACAAAATAAATATACAG
GCAATGGACGGTGGAGGCCTTTCTGCAAGATGTAGGGTTTTAGTGGAAGTATTGGACACC
AATGACAATCCCCCTGAACTGATCGTATCATCATTTTCCAACTCTGTTGCTGAGAATTCT
CCTGAGACGCCGCTGGCTGTTTTTAAGATTAATGACAGAGACTCTGGAGAAAATGGAAAG
ATGGTTTGCTACATTCAAGAGAATCTGCCATTCCTACTAAAACCTTCTGTGGAGAATTTT
TACATCCTAATTACAGAAGGCGCGCTGGACAGAGAGATCAGAGCCGAGTACAACATCACT
ATCACCGTCACTGACTTGGGGACACCCAGGCTGAAAACCGAGCACAACATAACGGTCCTG
GTCTCCGACGTCAATGACAACGCCCCCGCCTTCACCCAAACCTCCTACACCCTGTTCGTC
CGCGAGAACAACAGCCCCGCCCTGCACATCGGCAGCGTCAGCGCCACAGACAGAGACTCG
GGCACCAACGCCCAGGTCACCTACTCGCTGCTGCCGCCCCAAGACCCGCACCTGCCCCTC
GCCTCCCTGGTCTCCATCAACGCGGACAACGGCCACCTGTTCGCCCTCAGGTCGCTGGAC
TACGAGGCCCTGCAGGCTTTCGAGTTCCGCGTGGGCGCCACAGACCGCGGCTCCCCCGCG
CTGAGCAGAGAGGCGCTGGTGCGCGTGCTGGTGCTGGACGCCAACGACAACTCGCCCTTC
GTGCTGTACCCGCTGCAGAACGGCTCCGCGCCCTGCACCGAGCTGGTGCCCCGGGCGGCC
GAGCCGGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGGCGACTCGGGCCAGAACGCC
TGGCTGTCGTACCAGCTGCTCAAGGCCACGGAGCCCGGGCTGTTCGGTGTGTGGGCGCAC
AATGGGGAGGTGCGCACCGCCAGGCTGCTGAGCGAGCGCGACGCAGCCAAGCACAGGCTC
GTGGTGCTTGTCAAGGACAATGGCGAGCCTCCTCGCTCGGCCACCGCCACGCTGCACTTG
CTCCTGGTGGACGGCTTCTCCCAGCCCTACCTGCCTCTCCCGGAGGCGGCCCCGGCCCAG
GCCCAGGCCGAGGCCGACTTGCTCACCGTCTACCTGGTGGTGGCGTTGGCCTCGGTGTCT
TCGCTCTTCCTCCTCTCGGTGCTCCTGTTCGTGGCGGTGCGGCTGTGCAGGAGGAGCAGG
GCGGCCTCGGTGGGTCGCTGCTCGGTGCCCGAGGGTCCTTTTCCAGGGCATCTGGTGGAC
GTGAGGGGCGCTGAGACCCTGTCCCAGAGCTACCAGTATGAGGTGTGTCTGACGGGAGGC
CCCGGGACCAGTGAGTTCAAGTTCTTGAAACCAGTTATTTCGGATATTCAGGCACAGGGC
CCTGGGAGGAAGGGTGAAGAAAATTCCACCTTCCGAAATAGCTTTGGATTTAATATTCAG
TAA
|
| Protein Properties |
|---|
| Number of Residues
| 800 |
| Molecular Weight
| 87619.8 |
| Theoretical pI
| 4.49 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin beta-10
MAVRELCFPRQRQVLFLFLFWGVSLAGSGFGRYSVTEETEKGSFVVNLAKDLGLAEGELA
ARGTRVVSDDNKQYLLLDSHTGNLLTNEKLDREKLCGPKEPCMLYFQILMDDPFQIYRAE
LRVRDINDHAPVFQDKETVLKISENTAEGTAFRLERAQDPDGGLNGIQNYTISPNSFFHI
NISGGDEGMIYPELVLDKALDREEQGELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAP
QFAQALYETQAPENSPIGFLIVKVWAEDVDSGVNAEVSYSFFDASENIRTTFQINPFSGE
IFLRELLDYELVNSYKINIQAMDGGGLSARCRVLVEVLDTNDNPPELIVSSFSNSVAENS
PETPLAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNIT
ITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDS
GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPA
LSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNA
WLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHL
LLVDGFSQPYLPLPEAAPAQAQAEADLLTVYLVVALASVSSLFLLSVLLFVAVRLCRRSR
AASVGRCSVPEGPFPGHLVDVRGAETLSQSYQYEVCLTGGPGTSEFKFLKPVISDIQAQG
PGRKGEENSTFRNSFGFNIQ
|
| External Links |
|---|
| GenBank ID Protein
| 5457027 |
| UniProtKB/Swiss-Prot ID
| Q9UN67 |
| UniProtKB/Swiss-Prot Entry Name
| PCDBA_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152489 |
| GeneCard ID
| PCDHB10 |
| GenAtlas ID
| PCDHB10 |
| HGNC ID
| HGNC:8681 |
| References |
|---|
| General References
| Not Available |