| Identification |
|---|
| HMDB Protein ID
| CDBP03108 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin beta-4 |
| Description
| Not Available |
| Synonyms
|
- PCDH-beta-4
|
| Gene Name
| PCDHB4 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHB4 |
| Gene Sequence
|
>2388 bp
ATGAAGAAGCTAGGGAGAATTCATCCAAACAGGCAAGTGTTGGCCTTTATTTTGATGGTG
TTCTTGTCTCAGGTTCGCCTCGAGCCTATTCGTTATTCTGTGTTGGAGGAAACAGAGAGC
GGCTCCTTTGTAGCCCATCTGGCCAAGGATCTGGGCCTGGGAATTGGGGAACTGGCCTCC
CGGTCAGCCCGGGTGCTGTCTGACGATGACAAGCAGCGTTTGCAGCTGGATCGTCAGACT
GGAGATTTGCTTCTGAGGGAGAAACTAGACCGGGAAGAGCTCTGTGGTCCTATTGAACCG
TGTGTACTGCATTTCCAAGTGTTCCTGGAAATGCCGGTGCAATTTTTTCAAGGAGAATTA
TTGATCCAGGACATAAATGATCACTCTCCAATATTCCCTGAAAGGGAAGTGCTCTTGAAA
ATACTAGAAAATAGCCAGCCGGGTACTCTATTTCCGTTGCTAATAGCTGAGGATTTGGAT
GTGGGCAGCAATGGTCTTCAAAAATACACAATCAGCCCCAATTCTCATTTTCACATTCTC
ACTCGAAATCATAGTGAGGGCAAGAAATACCCAGATTTGGTGCAGGACAAACCACTGGAT
CGAGAGGAGCAGCCTGAGTTCAGCTTAACCCTCGTGGCGCTGGATGGTGGGTCACCACCT
AGGTCTGGCACGGTCATGGTTCGAATCCTGATCATGGACATCAATGACAATGCTCCTGAG
TTTGTGCACACTCCATATGGGGTGCAGGTCCTGGAAAACAGCCCCCTAGACTCTCCAATT
GTTAGGGTCTTAGCTAGAGATATAGATGCTGGAAACTTCGGGAGTGTTTCTTATGGCTTA
TTCCAAGCATCAGATGAAATTAAACAAACTTTCTCAATAAATGAAGTCACGGGAGAAATA
CTGTTGAAAAAAAAATTGGATTTCGAAAAAATTAAATCTTACCATGTAGAAATTGAGGCC
ACAGATGGAGGAGGCCTTTCTGGAAAAGGCACTGTAGTCATAGAGGTGGTGGATGTGAAT
GACAATCCCCCAGAACTTATCATATCTTCACTCACCAGCTCCATCCCAGAAAATGCTCCT
GAGACGGTAGTCTCTATCTTCCGAATTCGAGATAGAGATTCCGGAGAAAATGGAAAGATG
ATTTGCTCTATTCCAGATAATCTACCGTTTATTCTAAAACCAACTTTGAAGAATTTTTAC
ACCCTGGTAACAGAGAGACCACTGGACCGAGAGACCAGCGCTGAGTACAACATCACCATC
GCCGTCACTGACTTGGGGACACCCAGGCTGAAAACCCAGCAGAACATAACCGTGCAGGTC
TCCGACGTCAATGACAACGCCCCCGCCTTCACCCAAACCTCCTACACCCTGTTCGTCCGC
GAGAACAACAGCCCCGCCCTGCACATCGGCAGTGTCAGCGCCACAGACAGAGACTCGGGC
ACCAACGCCCAGGTCACCTACTCGCTGCTGCCGCCCCAGGACCCGCACCTGCCCCTCGCC
TCCCTGGTCTCCATCAACGCAGACAACGGCCACCTGTTCGCCCTCAGGTCGCTGGACTAC
GAGGCCCTGCAGGCGTTCGAGTTCCGCGTGGGCGCCTCAGACCGCGGTTCTCCGGCTTTG
AGCAGCGAGGCGCTGGTGCGCGTGCTGGTGCTGGACACCAACGACAACTCGCCCTTCGTG
CTGTACCCGCTGCAGAATGGCTCCGCGCCCTGCACCGAGCTGGTGCCCCGGGCGGCCGAG
CCGGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGGCGACTCGGGCCAGAACGCCTGG
CTGTCGTACCAGCTGCTCAAGGCCACGGAGCCTGGGCTGTTCGGCGTGTGGGCGCACAAT
GGCGAGGTGCGCACCGCCAGGCTGCTGAGCGAGCGCGACGCAGCCAAGCACAGGCTCGTG
GTGCTTGTCAAGGACAATGGCGAGCCTCCGCGCTCGGCCACCGCCACGCTGCACGTGCTC
CTGGTGGATGGCTTCTCCCAGCCCTACCTGCCTCTCCCTGAGGCGGCCCCGGCCCAGGCC
CAGGCCGACTCTCTCACCGTCTACCTGGTGGTGGCGTTGGCCTCGGTGTCGTCGCTCTTC
CTCTTCTCGGTGCTCCTGTTCGTGGCGGTGCGGCTGTGCAGGAGGAGCAGGGCGGCCTCG
GTGGGTCGCTGCTCGGTGCCCGAGGGCCCCTTTCCAGGGCATCTGGTGGACGTAAGCGGC
ACCGGGACCCTGTCCCAGAGCTACCAGTACGAGGTGTGTCTGACAGGAGACTCTGGGACT
GGTGAGTTCAAGTTCCTGAAGCCAATATTTCCTAATCTCTTGGTTCAGGACACCGGGAGG
GAAGTTAAGGAAAACCCCAAGTTCAGAAATAGCTTGGTATTCAGTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 795 |
| Molecular Weight
| 87269.3 |
| Theoretical pI
| 4.83 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin beta-4
MKKLGRIHPNRQVLAFILMVFLSQVRLEPIRYSVLEETESGSFVAHLAKDLGLGIGELAS
RSARVLSDDDKQRLQLDRQTGDLLLREKLDREELCGPIEPCVLHFQVFLEMPVQFFQGEL
LIQDINDHSPIFPEREVLLKILENSQPGTLFPLLIAEDLDVGSNGLQKYTISPNSHFHIL
TRNHSEGKKYPDLVQDKPLDREEQPEFSLTLVALDGGSPPRSGTVMVRILIMDINDNAPE
FVHTPYGVQVLENSPLDSPIVRVLARDIDAGNFGSVSYGLFQASDEIKQTFSINEVTGEI
LLKKKLDFEKIKSYHVEIEATDGGGLSGKGTVVIEVVDVNDNPPELIISSLTSSIPENAP
ETVVSIFRIRDRDSGENGKMICSIPDNLPFILKPTLKNFYTLVTERPLDRETSAEYNITI
AVTDLGTPRLKTQQNITVQVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSG
TNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGASDRGSPAL
SSEALVRVLVLDTNDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAW
LSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVL
LVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAAS
VGRCSVPEGPFPGHLVDVSGTGTLSQSYQYEVCLTGDSGTGEFKFLKPIFPNLLVQDTGR
EVKENPKFRNSLVFS
|
| External Links |
|---|
| GenBank ID Protein
| 5457043 |
| UniProtKB/Swiss-Prot ID
| Q9Y5E5 |
| UniProtKB/Swiss-Prot Entry Name
| PCDB4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152497 |
| GeneCard ID
| PCDHB4 |
| GenAtlas ID
| PCDHB4 |
| HGNC ID
| HGNC:8689 |
| References |
|---|
| General References
| Not Available |