| Identification |
|---|
| HMDB Protein ID
| CDBP03106 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin beta-2 |
| Description
| Not Available |
| Synonyms
|
- PCDH-beta-2
|
| Gene Name
| PCDHB2 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHB2 |
| Gene Sequence
|
>2397 bp
ATGGAGGCCGGAGAGGGGAAGGAGCGCGTTCCGAAACAAAGGCAAGTCCTGATATTCTTT
GTTTTGCTGGGCATAGCTCAGGCTAGTTGCCAGCCTAGGCACTATTCAGTGGCCGAGGAA
ACGGAGAGTGGCTCCTTTGTGGCCAATTTGTTAAAAGACCTGGGGCTGGAGATAGGAGAA
CTTGCTGTGAGGGGGGCCAGGGTCGTTTCCAAAGGAAAAAAAATGCATTTGCAGTTCGAT
AGGCAGACCGGGGATTTGTTGTTAAATGAGAAATTGGACCGGGAGGAGCTGTGCGGCCCC
ACAGAGCCCTGTGTCCTACCTTTCCAGGTGTTACTAGAAAATCCCTTGCAGTTTTTTCAG
GCGGAGCTACGGATTAGGGACGTAAATGATCATTCCCCAGTTTTCCTAGACAAAGAAATA
CTTTTGAAAATTCCAGAAAGTATCACTCCTGGAACTACTTTCTTAATAGAACGTGCCCAG
GACTTGGATGTAGGAACCAACAGTCTCCAAAATTACACAATCAGTCCCAATTTCCACTTT
CATCTTAATTTACAAGACAGTCTCGATGGCATAATATTACCACAGCTGGTGCTGAACAGA
GCCCTGGATCGCGAGGAGCAGCCTGAGATCAGGTTAACCCTCACAGCGCTAGATGGCGGG
AGTCCACCCAGGTCCGGCACGGCCCTGGTACGGATTGAAGTTGTGGACATCAATGACAAC
GTCCCAGAGTTTGCAAAGCTGCTCTATGAGGTGCAGATCCCGGAGGACAGCCCCGTTGGA
TCCCAGGTTGCCATCGTCTCTGCCAGGGATTTAGACATTGGAACTAATGGAGAAATATCT
TATGCATTTTCCCAAGCATCTGAAGACATTCGCAAAACGTTTCGATTAAGTGCAAAATCG
GGAGAACTGCTTTTAAGACAGAAACTGGATTTCGAATCCATCCAGACATACACAGTAAAT
ATTCAGGCGACAGATGGTGGGGGCCTATCTGGAACTTGTGTGGTATTTGTCCAAGTGATG
GATTTGAATGACAATCCTCCGGAACTAACTATGTCGACACTTATCAATCAGATCCCAGAA
AACTTGCAGGACACCCTCATTGCTGTATTCAGCGTTTCAGATCCTGACTCCGGAGACAAC
GGAAGGATGGTGTGCTCCATCCAAGATGATCTTCCTTTTTTCTTGAAACCTTCTGTTGAG
AACTTTTACACTCTGGTGATAAGCACGGCCCTGGACCGGGAGACCAGATCCGAATACAAC
ATCACCATCACCGTCACCGACTTCGGGACACCCAGGCTGAAAACCGAGCACAACATAACC
GTGCTGGTCTCCGACGTCAATGACAACGCCCCCGCCTTCACCCAAACCTCCTACACCCTG
TTCGTCCGCGAGAACAACAGCCCCGCCCTGCACATCGGCAGCGTCAGCGCCACAGACAGA
GACTCGGGCACCAACGCCCAGGTCACCTACTCGCTGCTGCCGCCCCAGGACCCGCACCTG
CCCCTCGCCTCCCTGGTCTCCATCAACGCGGACAACGGCCACCTGTTCGCTCTCCAGTCG
CTGGACTACGAGGCCCTGCAGGCGTTCGAGTTCCGCGTGGGCGCCGCAGACCGCGGCTCC
CCGGCGTTGAGCAGCGAGGCGCTGGTGCGCGTGCTGGTGCTGGACGCCAACGACAACTCG
CCCTTCGTGCTGTACCCGCTGCAGAACGGCTCCGCGCCCTGCACCGAGCTGGTGCCCCGG
GCGGCCGAGCCGGGCTACCTGGTGACCAAGGTGGTGGCGGTGGACGGCGACTCGGGCCAG
AACGCCTGGCTGTCGTACCAGCTGCTCAAGGCCACGGAGCCCGGGCTGTTCGGCGTGTGG
GCGCACAATGGCGAGGTGCGCACCGCCAGGCTGCTGAGGGAGCGCGACGCTGCCAAGCAG
AGGCTGGTGGTGCTGGTCAAGGACAATGGCGAGCCTCCGCGCTCGGCCACCGCCACGCTG
CACGTGCTCCTGGTGGACGGCTTCTCCCAGCCCTACCTGCTGCTCCCGGAGGCGGCACCG
GCCCAGGCCCAGGCCGACTTGCTCACCGTCTACCTGGTGGTGGCGTTGGCCTCGGTGTCT
TCGCTCTTCCTCTTCTCGGTGCTCCTGTTCGTGGCGGTGCGGCTGTGCAGGAGGAGCAGG
GCGGCCTCGGTGGGTCGCTGCTCGGTGCCCGAGGGCCCCTTTCCAGGGCAGATGGTGGAC
GTGAGCGGCACCGGGACCCTGTCCCAGAGCTACCAGTACGAGGTGTGTCTGACTGGAGGC
TCCGGGACAAATGAGTTCAAGTTCCTGAAGCCAATTATCCCCAACTTCGTTGCTCAGGGT
GCAGAGAGGGTTAGCGAGGCAAATCCCAGTTTCAGGAAGAGCTTTGAATTCACTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 798 |
| Molecular Weight
| 87252.9 |
| Theoretical pI
| 4.5 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin beta-2
MEAGEGKERVPKQRQVLIFFVLLGIAQASCQPRHYSVAEETESGSFVANLLKDLGLEIGE
LAVRGARVVSKGKKMHLQFDRQTGDLLLNEKLDREELCGPTEPCVLPFQVLLENPLQFFQ
AELRIRDVNDHSPVFLDKEILLKIPESITPGTTFLIERAQDLDVGTNSLQNYTISPNFHF
HLNLQDSLDGIILPQLVLNRALDREEQPEIRLTLTALDGGSPPRSGTALVRIEVVDINDN
VPEFAKLLYEVQIPEDSPVGSQVAIVSARDLDIGTNGEISYAFSQASEDIRKTFRLSAKS
GELLLRQKLDFESIQTYTVNIQATDGGGLSGTCVVFVQVMDLNDNPPELTMSTLINQIPE
NLQDTLIAVFSVSDPDSGDNGRMVCSIQDDLPFFLKPSVENFYTLVISTALDRETRSEYN
ITITVTDFGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDR
DSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALQSLDYEALQAFEFRVGAADRGS
PALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQ
NAWLSYQLLKATEPGLFGVWAHNGEVRTARLLRERDAAKQRLVVLVKDNGEPPRSATATL
HVLLVDGFSQPYLLLPEAAPAQAQADLLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSR
AASVGRCSVPEGPFPGQMVDVSGTGTLSQSYQYEVCLTGGSGTNEFKFLKPIIPNFVAQG
AERVSEANPSFRKSFEFT
|
| External Links |
|---|
| GenBank ID Protein
| 5457039 |
| UniProtKB/Swiss-Prot ID
| Q9Y5E7 |
| UniProtKB/Swiss-Prot Entry Name
| PCDB2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152495 |
| GeneCard ID
| PCDHB2 |
| GenAtlas ID
| PCDHB2 |
| HGNC ID
| HGNC:8687 |
| References |
|---|
| General References
| Not Available |