| Identification |
|---|
| HMDB Protein ID
| CDBP03105 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin beta-1 |
| Description
| Not Available |
| Synonyms
|
- PCDH-beta-1
|
| Gene Name
| PCDHB1 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| homophilic cell adhesion |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHB1 |
| Gene Sequence
|
>2457 bp
ATGGCGGGTACGCGCAGAAAATCTTTGCAAAACAGGCAAGTGGGATCTCTTCTCATTTTT
CTGTGCATATCTGTGGGGGATGCGACAACTATCCGCTATTCAGTGGCAGAGGAAATGGAG
AGCGGCTCGTTTGTGGCCAACGTAGCTAAGGACCTAGGACTGGAGGTAGGGAAGCTGGCT
GCGCGCGGGGCGCGGCTGGTTTCCGAGGGCAACAAAATGCATTTCCGGCTCCACCGCAAG
ACGGGAGATTTGTTTGTGAAGGAGAAACTGGATCGGGAGTCACTTTGTGGCAAAGCCGAC
CCTTGTGTTCTGCACTTTGAAGTAGTCCTGGTGGAGCCGCTGCAGTCCTTCCGGGCCGAG
GTCAGGGTATTTGATATCAATGACAATGCCCCAGTTTTCCTAAACAAGGAGCCGCTTTTA
AAGATTCCGGAGAGCACCCCTTTGGGTTCACGTTTTCCTCTGCAGAGCGCCCAGGATCTG
GACGTGGGCCTTAACGGTCTCCAGAACTACACCCTGAGTGCCAATGGGTATTTCCACCTG
CACACCCGCTTCTGCAGCCACGGGCCTAAATATGCTGAGCTGGTGCTGAACAAACCCCTG
GACCGAGAGGAGCAGCCTGAAGTCAACTTGACAATTACGGCGGTGGACGGCGGGTCCCCG
CCTAAGTCTGGCACAGCTCACATCCACGTGGTGGTTCTGGATGTCAACGACCACGTGCCC
CAGTTCTCGCGACTGGTGTACAGAGCCCAGGTATCAGAGAACAGCCCCAATGGCTCTTTG
GTGGCCACGGTGACTGCCGTGGACCTAGACGAGGGCACCAACAAAGCGATAACTTACTCT
TTAGCTCAAAACCCAGAAGCAATTCTCAAGACGTTTCAGATTGACCCTCAAAATGGAGAA
GTTCGACTAAGAGGACCCCTCGATTTTGAAGCCATTGAAACATACGACATTGACATTCAA
GCTACAGATGGTGGAGGCCTCTCTGCCCACAGCAAAGTCCTGGTAGAAGTGGTGGATGTG
AATGACAATCCTCCCGAAGTGATGGTCTCCTCTGTGTCCAGCCCACTCCCTGAAGACTCA
CCACCACAGACAGTAGTAGCCCTTTTCACTATCAGAGACCGGGACATTCGAGTGGGAGGA
AAAGTCACCTGCTTCCTCAGAGAAGACCTTCCCTTTGTAATCAAACCTACATTTGGGAAT
TCTTACTCACTGGTCACTGACAGAAGCTTGGATCGGGAGGAGGTCTCAGGCTATAATATC
ACCATTGTTGCCATGGATACTGGACCACCTAGCTTGTCTGCCGAGACTATGATAGAGGTG
CTAATATCCGACGTTAATGACAATCCTCCAATATTTCGGGAAGATTCCTATATCTTGACT
GTTCGAGAAAACAACAGTCCTGCGGTTTTTATTGGCAAAGTCCATGCTGAGGATCTTGAT
TTGGGTGAGAATGCCCAAATAACATATTCTCTGTTGCCTCCAAAAAACGGAGATCTTTCA
GTCTTTGCTTACATATCCATAAATTCAGGCAATGGGAAGCTCTACGCGCTGAGAACCATG
GATTATGAGGCCATTCAAGATTTTCAATTTGTGGTAAAGGCAACTGATGGGGGCTTCCTG
TCACTGAGTAGCCAAGTTACTGTCAGAGTGGTTGTCCTAGATGACAATGACAATCGTCCA
ATGATCTTATACCCACTGCAGAACGGCACCTTGCCCTGCAATGACCTGGTGCCCAGGTCT
GCAGAGGCAGGCTACCTAGTGACCAAAGTGGTGGCTGTGGATGGTGACTCAGGTCAGAAT
TCTTGGCTTTCATATCATCTACTTAAGGCCACTGACCTTGGGTTATTTTCTGTTCAAAGA
CAAAATGGAGAAATCCATACATTAAGGCAGATATCTGAGAGAGACCCCATGATGCAGAAA
TTGATCATTCTTGTTCAGGATCACGGCCAACCAGCTCTTTCCACTACTGTCTCACTCAAC
ATCCTGCTGGTAGATGGCTTTTCAGAGCCCTACCTGCAGTTCCAGGATCCAACCAAGCAT
TCTAGAAAGGTAAATCCATCCACTAAATATTTGGTCATTTCTCTGGTCATCCTTTCCTTT
CTCTTTCTCCTCTCTGTCATAGTGATCTTCATTATACATGTCTACCAAAAGATTAAATAT
AGAGAAAAGTTCACAATTCAAGAGCATTTCTATGATGACTGTAATTTCTCTAACAACCTG
GTACAAGGACAAGGCAATGGATCCTTATCTCGGCCTTGTCCATATGAAATGTGTTCAGCC
ACTGGCACTGGTAATAGTGAGTTTCGCTTTCTTAAGCGTTTTATGCCCAACTTGCCTTTC
CCTCATGCCACTGGGGAGATAAAAATGGAGGCTGGCTCCAGTTTGCCCCCAAATTCTGAT
AGGAATAAGTCTCAGAGATTAGAGGGCCATGACCAGGTATCTGATGACTATATGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 818 |
| Molecular Weight
| 90489.8 |
| Theoretical pI
| 5.03 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin beta-1
MAGTRRKSLQNRQVGSLLIFLCISVGDATTIRYSVAEEMESGSFVANVAKDLGLEVGKLA
ARGARLVSEGNKMHFRLHRKTGDLFVKEKLDRESLCGKADPCVLHFEVVLVEPLQSFRAE
VRVFDINDNAPVFLNKEPLLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLSANGYFHL
HTRFCSHGPKYAELVLNKPLDREEQPEVNLTITAVDGGSPPKSGTAHIHVVVLDVNDHVP
QFSRLVYRAQVSENSPNGSLVATVTAVDLDEGTNKAITYSLAQNPEAILKTFQIDPQNGE
VRLRGPLDFEAIETYDIDIQATDGGGLSAHSKVLVEVVDVNDNPPEVMVSSVSSPLPEDS
PPQTVVALFTIRDRDIRVGGKVTCFLREDLPFVIKPTFGNSYSLVTDRSLDREEVSGYNI
TIVAMDTGPPSLSAETMIEVLISDVNDNPPIFREDSYILTVRENNSPAVFIGKVHAEDLD
LGENAQITYSLLPPKNGDLSVFAYISINSGNGKLYALRTMDYEAIQDFQFVVKATDGGFL
SLSSQVTVRVVVLDDNDNRPMILYPLQNGTLPCNDLVPRSAEAGYLVTKVVAVDGDSGQN
SWLSYHLLKATDLGLFSVQRQNGEIHTLRQISERDPMMQKLIILVQDHGQPALSTTVSLN
ILLVDGFSEPYLQFQDPTKHSRKVNPSTKYLVISLVILSFLFLLSVIVIFIIHVYQKIKY
REKFTIQEHFYDDCNFSNNLVQGQGNGSLSRPCPYEMCSATGTGNSEFRFLKRFMPNFPF
PHATGEIKMEAGSSLPPNSDRNKSQRLEGHDQVSDDYM
|
| External Links |
|---|
| GenBank ID Protein
| 5457025 |
| UniProtKB/Swiss-Prot ID
| Q9Y5F3 |
| UniProtKB/Swiss-Prot Entry Name
| PCDB1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF152488 |
| GeneCard ID
| PCDHB1 |
| GenAtlas ID
| PCDHB1 |
| HGNC ID
| HGNC:8680 |
| References |
|---|
| General References
| Not Available |