| Identification |
|---|
| HMDB Protein ID
| CDBP03098 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin alpha-7 |
| Description
| Not Available |
| Synonyms
|
- PCDH-alpha-7
|
| Gene Name
| PCDHA7 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHA7 |
| Gene Sequence
|
>2814 bp
ATGGTGTGCCCGAATGGATACGACCCAGGGGGCCGACATCTACTGCTGTTTATTATAATT
CTAGCAGCTTGGGAGGCAGGGAGAGGCCAGCTCCACTACTCGGTCCCCGAGGAGGCTAAA
CATGGCAACTTCGTGGGCCGCATCGCGCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTG
CCGCGCCTGTTCCGGGCGGTGTGCAAATTCCGTGGGGATCTTCTGGAGGTAAATCTGCAG
AATGGCATTTTGTTTGTGAATTCTCGGATCGACCGCGAGGAGCTGTGCGGGCGGAGCGCG
GAGTGCAGCATCCACCTGGAGGTGATCGTGGAAAGGCCGCTGCAGGTTTTCCATGTGGAC
GTGGAGGTGAAGGACATTAACGACAACCCTCCGGTGTTCCCAGCGACACAAAGGAATCTG
TTCATCGCGGAATCCAGGCCGCTTGACTCTCGGTTTCCACTAGAGGGCGCGTCCGATGCA
GATATCGGGGAGAACGCCCTGCTCACTTACAGACTGAGCCCCAATGAGTATTTCTTCCTG
GACGTGCCAACCAGCAACCAGCAGGTAAAACCTCTTGGACTTGTATTACGGAAACTTTTA
GACAGAGAAGAAACTCCGGAGCTTCATTTATTGCTCACGGCCACCGATGGAGGCAAACCC
GAGCTGACTGGCACCGTTCAATTACTCATCACGGTACTGGACAACAATGACAATGCCCCA
GTGTTCGACAGAACCCTGTATACGGTGAAATTACCAGAAAACGTTTCTATCGGAACGCTG
GTGATTCACCCCAATGCCTCAGATTTAGACGAAGGCTTGAATGGGGATATTATTTACTCC
TTCTCCAGTGATGTTTCTCCAGATATAAAATCCAAGTTCCACATGGACCCCTTAAGTGGG
GCAATCACAGTGATAGGACATATGGATTTTGAAGAAAGTAGAGCACACAAGATCCCAGTC
GAGGCTGTCGATAAAGGCTTCCCACCCCTGGCTGGTCATTGTACAGTTCTTGTGGAAGTT
GTGGATGTAAATGACAATGCTCCACAGTTGACTCTCACTTCCCTGTCTCTCCCTATTCCA
GAGGACGCCCAACCAGGTACCGTCATCACATTGATTAGCGTGTTTGACCGAGATTTTGGA
GTCAACGGACAGGTTACCTGCTCCCTGACGCCCCGCGTTCCCTTCAAGTTGGTGTCCACC
TTCAAGAATTACTATTCATTGGTGCTGGACAGCGCTCTGGACCGCGAGAGTGTGTCCGCC
TATGAGCTGGTGGTTACCGCGCGGGACGGGGGCTCGCCTTCTCTGTGGGCCACTGCTAGC
GTGTCCGTGGAGGTGGCCGACGTGAACGACAACGCCCCGGCGTTCGCGCAGCCCGAGTAT
ACGGTGTTCGTGAAGGAGAACAACCCGCCGGGCTGCCACATCTTCACTGTGTCGGCGGGG
GACGCGGACGCGCAGAAGAACGCGCTGGTGTCCTACTCGCTGGTGGAGCTGCGGGTGGGC
GAGCGCGCGCTGTCGAGCTACGTGTCAGTGCACGCGGAGAGCGGCAAGGTGTACGCGCTG
CAGCCGTTGGACCACGAGGAGCTGGAGCTGTTGCAGTTCCAGGTGAGCGCGCGCGATGCG
GGCGTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGAC
AACGCGCCGGCACTGCTGGCGCCTCGGGTGGGTGGCACTGGTGGCGCAGTGAGAGAGCTT
GTGCCGCGGTCTGTGGGCGCGGGCCATGTGGTGGCGAAGGTACGTGCAGTTGACGCTGAC
TCAGGCTACAACGCGTGGCTTTCGTATGAGTTGCAACCGGTGGCGGCCGGTGCGAGCATC
CCGTTCCGCGTGGGGCTGTACACTGGTGAGATCAGCACGACACGAGCCCTAGATGAGACG
GACGCACCGCGCCACCGCCTTCTGGTGCTTGTGAAGGACCACGGGGAGCCCTCGCTGACA
GCCACAGCCACCGTGCTGGTGTCGCTGGTGGAAAGCGGCCAGGCACCAAAGGCGTCGTCG
CGGGCATCGTTGGGCATTGCAGGCCCAGAGACCGAGCTGGTGGATGTCAACGTGTACCTG
ATCATCGCCATCTGCGCGGTGTCCAGTCTGTTGGTGCTTACCCTGCTGCTGTACACGGCG
TTGCGGTGCTCAGCGCCGTCCTCTGAGGGCGCATGTAGTTTGGTAAAGCCCACTCTGGTG
TGCTCCAGCGCGGTGGGGAGCTGGTCATTCTCCCAGCAGAGGCGGCAGAGGGTGTGCTCT
GGGGAGGGCCCACCCAAGACAGACCTCATGGCCTTCAGTCCCAGCCTTCCTCAGGGTCCA
TCCTCTACAGACAATCCACGACAGCCCAACCCTGACTGGCGTTACTCTGCCTCCCTGAGA
GCAGGCATGCACAGCTCTGTGCACCTAGAGGAGGCTGGCATTCTACGGGCTGGTCCAGGA
GGGCCTGATCAGCAGTGGCCAACAGTATCCAGTGCAACACCAGAACCAGAGGCAGGAGAA
GTGTCCCCTCCAGTCGGTGCGGGTGTCAACAGCAACAGCTGGACCTTTAAATACGGACCA
GGCAACCCCAAACAATCCGGTCCCGGTGAGTTGCCCGACAAATTCATTATCCCAGGATCT
CCTGCAATCATCTCCATCCGGCAGGAGCCTACTAACAGCCAAATTGACAAAAGTGACTTC
ATAACCTTCGGCAAAAAGGAGGAGACCAAGAAAAAGAAGAAAAAGAAGAAGGGTAACAAG
ACCCAGGAGAAAAAAGAGAAAGGGAACAGCACGACTGACAACAGTGACCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 937 |
| Molecular Weight
| 100864.0 |
| Theoretical pI
| 4.86 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin alpha-7
MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV
PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD
VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL
DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP
VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG
AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP
EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA
YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG
DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD
SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT
ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA
LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP
SSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE
VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF
ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
|
| External Links |
|---|
| GenBank ID Protein
| 9256594 |
| UniProtKB/Swiss-Prot ID
| Q9UN72 |
| UniProtKB/Swiss-Prot Entry Name
| PCDA7_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_018910.2 |
| GeneCard ID
| PCDHA7 |
| GenAtlas ID
| PCDHA7 |
| HGNC ID
| HGNC:8673 |
| References |
|---|
| General References
| Not Available |