| Identification |
|---|
| HMDB Protein ID
| CDBP03096 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin alpha-5 |
| Description
| Not Available |
| Synonyms
|
- PCDH-alpha-5
|
| Gene Name
| PCDHA5 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q31 |
| SNPs
| PCDHA5 |
| Gene Sequence
|
>2811 bp
ATGGTATATTCCCGGAGAGGAAGTCTGGGATCCCGGCTCCTGCTGCTCTGGCTTCTCCTT
GCCTACTGGAAGGCAGGGAGCGGCCAGCTCCACTACTCGATCCCGGAGGAAGCCAAACAC
GGAACCTTCGTTGGCCGCATCGCGCAGGACCTAGGGCTGGAGCTGGCGGAGCTGGTGCCG
CGCCTGTTCCGGGTGGCGTCCAAGGGCCGCGGGGACCTTCTGGAGGTAAATCTGCAGAAT
GGCATTTTGTTTGTGAATTCTCGGATCGACCGGGAGGAGCTGTGCCGGCGGAGGGCGGAG
TGCAGCATCCACCTGGAGGTGATCGTGGACAGGCCGCTGCAGGTTTTCCATGTGGAGGTG
GCAGTGAAGGACATCAATGACAATCCGCCCAGGTTCTCCAGACAAGAACAAAGATTATTC
ATTTTAGAGTCAAGAATGCCAGATTCGCGGTTTCCGCTAGAGGGCGCGTCGGATTTGGAT
ATTGGAGCAAATGCACAATTGAGATACAGGTTAAATCCAAACGAATATTTTGACTTAGAT
GTTAAAACAAATGAAGAAGAAACGAACTTTTTAGAGCTGGTTTTGAGGAAATCCTTAGAT
AGAGAAGAAACACAAGAACACCGTTTATTAGTGATTGCAACTGATGGAGGAAAACCCGAA
CTAACAGGTACAGTTCAGTTGTTGATCAATGTATTGGATGCTAATGATAACGCCCCAGAA
TTTGATAAATCCATTTATAATGTCAGATTGTTGGAAAATGCACCAAGTGGGACATTAGTT
ATTAAACTGAACGCCTCAGATGCAGATGAGGGCATCAATAAGGAAATAGTGTATTTCTTT
AGTAATCTTGTTCTTGACGATGTAAAGTCCAAATTTATAATTAATTCTAATACTGGTGAA
ATAAAAGTTAACGGGGAACTGGATTATGAAGACTATAACTCATATGAAATTAATATTGAT
GCCATGGATAAAAGTACATTCCCATTATCAGGACACTGTAAAGTAGTAGTGAAACTCCTG
GATGTGAATGATAATACCCCAGAGATGGCCATAACCACCCTTTTCCTGCCTGTCAAAGAG
GACGCTCCACTCAGCACGGTCATTGCTCTGATCAGCGTGTCTGACCGTGACTCAGGTGCC
AACGGGCAGGTGACCTGCTCCCTAATGCCCCACGTTCCCTTCAAGCTGGTGTCCACCTTC
AAGAATTACTACTCGTTGGTGCTGGACAGCGCCCTGGACCGCGAGAGCGTGTCGGTCTAT
GAGCTGGTGGTGACCGCGCGGGACGGGGGCTCGCCTTCGCTGTGGGCCACCGCCAGCGTG
TCTGTGGAAGTGGCCGACGTGAACGACAACGCTCCGGCGTTCGCGCAGCCCCAGTATACC
GTGTTCGTGAAGGAGAACAACCCGCCAGGCTGCCACATCTTCACGGTGTCTGCACGGGAC
GCGGACGCGCAGGAGAACGCCCTGGTGTCCTACTCGCTGGTGGAGCGGCGGGTGGGCGAG
CGCCCGCTGTCGAGTTACGTTTCGGTGCACGCGGAGAGCGGCAAGGTGTACGCGCTGCAG
CCGCTGGACCACGAGGAAGTGGAGCTGCTGCAGTTCCAGGTGAGCGCGCGCGACGCGGGC
GTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGACAAC
GCGCCGGCGCTGCTGGTGCCTCGAGTGGGTGGCACCGGCGGCGCAGTGAGCGAGCTGGTG
CCGAGGTCAGTGGGTGCGGGCCACGTGGTGGCGAAGGTGCGCGCAGTGGACCCTGATTCG
GGCTACAACGCTTGGCTTTCGTATGAGCTGCAGCCAGCGCCTGGCAGTGCGCGCATCCCG
TTCCGCGTGGGGCTGTACACAGGCGAGATCAGCACAACACGCTCTCTGGATGAGACCGAA
GCACCGCGCCACCGCCTTCTGGTGCTGGTGAAGGACCATGGAGAGCCCCCGCTGACAGCC
ACAGCCACAGTGCTGGTGTCGCTGGTGGAAAGTGGCCAGGCGCCGAAGGCCTCATCGCGG
GCGTCGGCGGGCGCTGTGGGTCCCGAGGCTGCCCTGGTGGATGTCAACGTGTACCTGATC
ATCGCCATCTGTGCGGTGTCCAGCCTGCTGGTGCTCACGCTGCTGCTGTACACCGCGCTG
CGGTGCTCGGCGCAGCCCACCGAGGCCGTGTGCACACGGGGCAAGCCCACTCTGTTGTGC
TCCAGCGCGGTGGGGAGCTGGTCGTACTCGCAGCAGAGGAGACAGAGGGTGTGCTCTGGG
GAAGCTCCACCCAAAACAGACCTCATGGCCTTCAGTCCAAGCCTTCCTCAGGGTCCCACC
TCTACAGACAACCCACGACAGCCCAACCCTGACTGGCGTTACTCTGCCTCCCTGAGAGCA
GGCATGCACAGCTCTGTGCACCTAGAGGAGGCTGGCATTCTACGGGCTGGTCCAGGAGGG
CCTGATCAGCAGTGGCCAACAGTATCCAGTGCAACACCAGAACCAGAGGCAGGAGAAGTG
TCCCCTCCAGTCGGTGCGGGTGTCAACAGCAACAGCTGGACCTTTAAATACGGACCAGGC
AACCCCAAACAATCCGGTCCCGGTGAGTTGCCCGACAAATTCATTATCCCAGGATCTCCT
GCAATCATCTCCATCCGGCAGGAGCCTACTAACAGCCAAATTGACAAAAGTGACTTCATA
ACCTTCGGCAAAAAGGAGGAGACCAAGAAAAAGAAGAAAAAGAAGAAGGGTAACAAGACC
CAGGAGAAAAAAGAGAAAGGGAACAGCACGACTGACAACAGTGACCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 936 |
| Molecular Weight
| 102047.2 |
| Theoretical pI
| 5.08 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin alpha-5
MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP
RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV
AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD
VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE
FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE
IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE
DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY
ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD
ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG
VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS
GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA
TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL
RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT
STDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEV
SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI
TFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
|
| External Links |
|---|
| GenBank ID Protein
| 9256590 |
| UniProtKB/Swiss-Prot ID
| Q9Y5H7 |
| UniProtKB/Swiss-Prot Entry Name
| PCDA5_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_018908.2 |
| GeneCard ID
| PCDHA5 |
| GenAtlas ID
| PCDHA5 |
| HGNC ID
| HGNC:8671 |
| References |
|---|
| General References
| Not Available |