| Identification |
|---|
| HMDB Protein ID
| CDBP03087 |
| Secondary Accession Numbers
| Not Available |
| Name
| Protocadherin-18 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| PCDH18 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Potential calcium-dependent cell-adhesion protein |
| GO Classification
|
| Component |
| membrane |
| cell part |
| plasma membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:4 |
| Locus
| 4q31 |
| SNPs
| PCDH18 |
| Gene Sequence
|
>3408 bp
ATGCACCAAATGAATGCTAAAATGCACTTTAGGTTTGTTTTTGCACTTCTGATAGTATCT
TTCAACCACGATGTACTGGGCAAGAATTTGAAATACAGGATTTATGAGGAACAGAGGGTT
GGATCAGTAATTGCAAGACTATCAGAGGATGTGGCTGATGTTTTATTGAAGCTTCCTAAT
CCTTCTACTGTTCGATTTCGAGCCATGCAGAGGGGAAATTCTCCTCTACTTGTAGTAAAC
GAGGATAATGGGGAAATCAGCATAGGGGCTACAATTGACCGTGAACAACTGTGCCAGAAA
AACTTGAACTGTTCCATAGAGTTTGATGTGATCACTCTACCCACAGAGCATCTGCAGCTT
TTCCATATTGAAGTTGAAGTGCTGGATATTAATGACAATTCTCCCCAGTTTTCAAGATCT
CTCATACCTATTGAGATATCTGAGAGTGCAGCAGTTGGGACTCGCATTCCCCTGGACAGT
GCATTTGATCCAGATGTTGGGGAAAATTCCCTCCACACATACTCGCTCTCTGCCAATGAT
TTTTTTAATATCGAGGTTCGGACCAGGACTGATGGAGCCAAGTATGCAGAACTCATAGTG
GTCAGAGAGTTAGATCGGGAGCTGAAGTCAAGCTACGAGCTTCAGCTCACTGCCTCAGAC
ATGGGAGTACCTCAGAGGTCTGGCTCATCCATACTAAAAATAAGCATTTCAGACTCCAAT
GACAACAGCCCTGCTTTTGAGCAGCAATCTTATATAATACAACTCTTAGAAAACTCCCCG
GTTGGCACTTTGCTCTTAGATCTGAATGCCACGGATCCAGATGAGGGCGCTAATGGGAAA
ATTGTATATTCCTTCAGCAGTCATGTGTCTCCCAAAATTATGGAGACTTTTAAAATTGAT
TCTGAAAGAGGACATTTGACTCTTTTCAAGCAAGTGGATTATGAAATCACCAAATCCTAT
GAGATTGATGTTCAGGCTCAAGATTTGGGTCCAAATTCAATCCCAGCCCATTGCAAAATT
ATAATTAAGGTTGTGGATGTTAATGACAATAAACCTGAAATTAACATCAACCTCATGTCC
CCTGGAAAAGAAGAAATATCTTATATTTTTGAAGGGGATCCTATTGATACATTTGTTGCT
TTGGTCAGAGTTCAGGACAAGGATTCTGGGCTGAATGGAGAAATAGTTTGTAAGCTTCAT
GGACATGGTCACTTTAAACTTCAGAAGACATATGAAAACAATTATTTAATCTTAACTAAT
GCCACACTGGATAGAGAAAAGAGATCTGAGTATAGTTTGACTGTAATCGCTGAGGACAGG
GGGACACCCAGTCTCTCTACAGTGAAACATTTTACAGTTCAAATCAATGATATCAATGAC
AATCCACCCCACTTCCAGAGAAGCCGATATGAATTTGTAATTTCAGAAAATAACTCACCA
GGGGCATATATCACCACTGTTACAGCCACAGATCCTGATCTTGGAGAAAATGGGCAAGTG
ACATACACCATCTTGGAGAGTTTTATTCTAGGAAGTTCCATAACTACATATGTAACCATT
GACCCATCTAATGGAGCCATCTATGCCCTCAGAATCTTTGATCATGAAGAAGTGAGTCAG
ATCACTTTTGTGGTAGAAGCAAGAGATGGAGGAAGCCCGAAGCAACTGGTAAGCAATACC
ACAGTTGTGCTCACCATCATTGACGAAAATGACAACGTTCCTGTGGTTATAGGGCCTGCA
TTGCGTAATAATACGGCAGAAATCACCATTCCCAAAGGGGCTGAAAGTGGCTTTCATGTC
ACAAGAATAAGGGCAATTGACAGAGACTCTGGTGTGAATGCTGAACTCAGCTGCGCCATA
GTAGCAGGTAATGAGGAGAATATCTTCATAATTGATCCACGATCATGTGACATCCATACC
AACGTTAGCATGGATTCTGTTCCCTACACAGAATGGGAGCTGTCAGTTATCATTCAGGAC
AAAGGCAATCCTCAGCTACATACCAAAGTCCTTCTGAAGTGCATGATCTTTGAATATGCA
GAGTCGGTGACAAGTACAGCAATGACTTCAGTAAGCCAGGCATCCTTGGATGTCTCCATG
ATAATAATTATTTCCTTAGGAGCAATTTGTGCAGTGTTGCTGGTTATTATGGTGCTATTT
GCAACTAGGTGTAACCGCGAGAAGAAAGACACTAGATCCTATAACTGCAGGGTGGCCGAA
TCAACTTACCAGCACCACCCAAAAAGGCCATCCCGGCAGATTCACAAAGGGGACATCACA
TTGGTGCCTACCATAAATGGCACTCTGCCCATCAGATCTCATCACAGATCGTCTCCATCT
TCATCTCCTACCTTAGAAAGAGGGCAGATGGGCAGCCGGCAGAGTCACAACAGTCACCAG
TCACTCAACAGTTTGGTGACAATCTCATCAAACCACGTGCCAGAGAATTTCTCATTAGAA
CTCACCCACGCCACTCCTGCTGTTGAGCAGGTCTCTCAGCTTCTTTCAATGCTTCACCAG
GGGCAATATCAGCCAAGACCAAGTTTTCGAGGAAACAAATATTCCAGGAGCTACAGATAT
GCCCTTCAAGACATGGACAAATTTAGCTTGAAAGACAGTGGCCGTGGTGACAGTGAGGCA
GGAGACAGTGATTATGATTTGGGGCGAGATTCTCCAATAGATAGGCTGTTGGGTGAAGGA
TTCAGCGACCTGTTTCTCACAGATGGAAGAATTCCAGCAGCTATGAGACTCTGCACGGAG
GAGTGCAGGGTCCTGGGACACTCTGACCAGTGCTGGATGCCACCACTGCCCTCACCGTCT
TCTGATTATAGGAGTAACATGTTCATTCCAGGGGAAGAATTCCCAACGCAACCCCAGCAG
CAGCATCCACATCAGAGTCTTGAGGATGACGCTCAGCCTGCAGATTCCGGTGAAAAGAAG
AAGAGTTTTTCCACCTTTGGAAAGGACTCCCCAAACGATGAGGACACTGGGGATACCAGC
ACATCATCTCTGCTCTCGGAAATGAGCAGTGTGTTCCAGCGTCTCTTACCGCCTTCCCTG
GACACCTATTCTGAATGCAGTGAGGTGGATCGGTCCAACTCCCTGGAGCGCAGGAAGGGA
CCCTTGCCAGCCAAAACTGTGGGTTACCCACAGGGGGTAGCGGCATGGGCAGCCAGTACG
CATTTTCAAAATCCCACCACCAACTGTGGGCCGCCACTTGGAACTCACTCCAGTGTGCAG
CCTTCTTCAAAATGGCTGCCAGCCATGGAGGAGATCCCTGAAAATTATGAGGAAGATGAT
TTTGACAATGTGCTCAACCACCTCAATGATGGGAAACACGAACTCATGGATGCCAGTGAA
CTGGTGGCAGAGATTAACAAACTGCTTCAAGATGTCCGCCAGAGCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 1135 |
| Molecular Weight
| 126148.0 |
| Theoretical pI
| 4.78 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protocadherin-18
MHQMNAKMHFRFVFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPN
PSTVRFRAMQRGNSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQL
FHIEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSAND
FFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSN
DNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKID
SERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMS
PGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTN
ATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSP
GAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQ
ITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHV
TRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQD
KGNPQLHTKVLLKCMIFEYAESVTSTAMTSVSQASLDVSMIIIISLGAICAVLLVIMVLF
ATRCNREKKDTRSYNCRVAESTYQHHPKRPSRQIHKGDITLVPTINGTLPIRSHHRSSPS
SSPTLERGQMGSRQSHNSHQSLNSLVTISSNHVPENFSLELTHATPAVEQVSQLLSMLHQ
GQYQPRPSFRGNKYSRSYRYALQDMDKFSLKDSGRGDSEAGDSDYDLGRDSPIDRLLGEG
FSDLFLTDGRIPAAMRLCTEECRVLGHSDQCWMPPLPSPSSDYRSNMFIPGEEFPTQPQQ
QHPHQSLEDDAQPADSGEKKKSFSTFGKDSPNDEDTGDTSTSSLLSEMSSVFQRLLPPSL
DTYSECSEVDRSNSLERRKGPLPAKTVGYPQGVAAWAASTHFQNPTTNCGPPLGTHSSVQ
PSSKWLPAMEEIPENYEEDDFDNVLNHLNDGKHELMDASELVAEINKLLQDVRQS
|
| External Links |
|---|
| GenBank ID Protein
| 14589929 |
| UniProtKB/Swiss-Prot ID
| Q9HCL0 |
| UniProtKB/Swiss-Prot Entry Name
| PCD18_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_019035.3 |
| GeneCard ID
| PCDH18 |
| GenAtlas ID
| PCDH18 |
| HGNC ID
| HGNC:14268 |
| References |
|---|
| General References
| Not Available |