| Identification |
|---|
| HMDB Protein ID
| CDBP03063 |
| Secondary Accession Numbers
| Not Available |
| Name
| Neuronal pentraxin-1 |
| Description
| Not Available |
| Synonyms
|
- NP-I
- NP1
- Neuronal pentraxin I
|
| Gene Name
| NPTX1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in metal ion binding |
| Specific Function
| May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cytoplasmic vesicle
- secretory vesicle (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17q25.3 |
| SNPs
| NPTX1 |
| Gene Sequence
|
>1299 bp
ATGCCGGCCGGCCGCGCCGCGCGCACCTGTGCGCTGCTCGCCCTCTGCCTCCTGGGCGCC
GGGGCCCAGGATTTCGGGCCGACGCGCTTCATCTGCACCTCGGTGCCCGTGGACGCCGAC
ATGTGCGCCGCGTCCGTGGCCGCCGGCGGCGCCGAGGAGCTCCGGAGCAGCGTGCTGCAG
CTCCGCGAGACGGTGCTGCAGCAGAAGGAGACCATCCTGAGCCAGAAGGAGACCATCCGC
GAGCTGACCGCCAAGCTGGGCCGCTGCGAGAGCCAGAGCACGCTGGACCCCGGAGCCGGC
GAGGCCCGGGCGGGCGGCGGCCGCAAGCAGCCCGGCTCGGGCAAGAACACCATGGGCGAC
CTGTCCCGGACACCGGCCGCCGAGACGCTCAGCCAACTCGGGCAAACTTTGCAATCGCTC
AAAACCCGCCTGGAGAACCTCGAGCAGTACAGCCGCCTCAATTCCTCCAGCCAGACCAAC
AGCCTCAAGGATCTGCTGCAGAGCAAGATCGATGAGCTGGAGAGGCAGGTGCTGTCCCGG
GTGAACACCCTGGAGGAGGGCAAGGGGGGCCCCAGGAACGACACCGAGGAGAGGGTCAAG
ATCGAGACCGCCCTGACCTCCCTGCACCAGCGGATCAGCGAGCTCGAGAAAGGTCAGAAA
GACAACCGCCCTGGAGACAAGTTCCAGCTCACATTCCCACTGCGGACCAACTATATGTAT
GCCAAGGTGAAGAAGAGCCTGCCAGAGATGTACGCCTTCACTGTCTGCATGTGGCTCAAG
TCCAGCGCCACGCCAGGTGTGGGCACGCCCTTCTCCTACGCTGTGCCCGGCCAGGCCAAC
GAGCTGGTCCTCATTGAGTGGGGCAACAACCCCATGGAGATCCTCATCAATGACAAGGTG
GCCAAGCTGCCTTTTGTCATCAATGATGGCAAGTGGCACCACATCTGTGTCACCTGGACC
ACCCGGGACGGGGTCTGGGAGGCCTACCAGGATGGCACGCAGGGTGGCAGTGGCGAGAAC
TTGGCGCCCTATCACCCCATCAAGCCCCAGGGCGTGCTGGTGCTGGGCCAGGAGCAGGAC
ACTCTGGGTGGTGGGTTTGATGCCACCCAGGCATTTGTGGGTGAGCTGGCCCACTTCAAC
ATCTGGGACCGCAAGCTGACCCCCGGGGAGGTGTACAACCTGGCCACCTGCAGCACCAAG
GCTCTGTCCGGCAATGTCATCGCCTGGGCTGAATCCCACATCGAGATCTACGGCGGGGCC
ACCAAGTGGACCTTCGAGGCCTGTCGCCAGATCAACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 432 |
| Molecular Weight
| 47122.0 |
| Theoretical pI
| 6.52 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Neuronal pentraxin-1
MPAGRAARTCALLALCLLGAGAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSSVLQ
LRETVLQQKETILSQKETIRELTAKLGRCESQSTLDPGAGEARAGGGRKQPGSGKNTMGD
LSRTPAAETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDELERQVLSR
VNTLEEGKGGPRNDTEERVKIETALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMY
AKVKKSLPEMYAFTVCMWLKSSATPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKV
AKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGSGENLAPYHPIKPQGVLVLGQEQD
TLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSTKALSGNVIAWAESHIEIYGGA
TKWTFEACRQIN
|
| External Links |
|---|
| GenBank ID Protein
| 193785332 |
| UniProtKB/Swiss-Prot ID
| Q15818 |
| UniProtKB/Swiss-Prot Entry Name
| NPTX1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK127335 |
| GeneCard ID
| NPTX1 |
| GenAtlas ID
| NPTX1 |
| HGNC ID
| HGNC:7952 |
| References |
|---|
| General References
| Not Available |