Showing Protein Nuclear factor of activated T-cells, cytoplasmic 3 (CDBP03054)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03054
Secondary Accession Numbers Not Available
Name Nuclear factor of activated T-cells, cytoplasmic 3
Description Not Available
Synonyms
  1. NF-AT4
  2. NF-ATc3
  3. NFATc3
  4. NFATx
  5. T-cell transcription factor NFAT4
Gene Name NFATC3
Protein Type Transcription Factor
Biological Properties
General Function Involved in sequence-specific DNA binding transcription factor activity
Specific Function Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2
GO Classification
Component
organelle
membrane-bounded organelle
intracellular membrane-bounded organelle
nucleus
Function
sequence-specific dna binding transcription factor activity
Process
regulation of macromolecule metabolic process
regulation of gene expression
regulation of transcription
regulation of transcription, dna-dependent
biological regulation
regulation of biological process
regulation of metabolic process
Cellular Location
  1. Nucleus
  2. Cytoplasm
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 16q22.2
SNPs NFATC3
Gene Sequence 
>3228 bp
ATGACTACTGCAAACTGTGGCGCCCACGACGAGCTCGACTTCAAACTCGTCTTTGGCGAG
GACGGGGCGCCGGCGCCGCCGCCCCCGGGCTCGCGGCCTGCAGATCTTGAGCCAGATGAT
TGTGCATCCATTTACATCTTTAATGTAGATCCACCTCCATCTACTTTAACCACACCACTT
TGCTTACCACATCATGGATTACCGTCTCACTCTTCTGTTTTGTCACCATCGTTTCAGCTC
CAAAGTCACAAAAACTATGAAGGAACTTGTGAGATTCCTGAATCTAAATATAGCCCATTA
GGTGGTCCCAAACCCTTTGAGTGCCCAAGTATTCAAATTACATCTATCTCTCCTAACTGT
CATCAAGAATTAGATGCACATGAAGATGACCTACAGATAAATGACCCAGAACGGGAATTT
TTGGAAAGGCCTTCTAGAGATCATCTCTATCTTCCTCTTGAGCCATCCTACCGGGAGTCT
TCTCTTAGTCCTAGTCCTGCCAGCAGCATCTCTTCTAGGAGTTGGTTCTCTGATGCATCT
TCTTGTGAATCGCTTTCACATATTTATGATGATGTGGACTCAGAGTTGAATGAAGCTGCA
GCCCGATTTACCCTTGGATCCCCTCTGACTTCTCCTGGTGGCTCTCCAGGGGGCTGCCCT
GGAGAAGAAACTTGGCATCAACAGTATGGACTTGGACACTCATTATCACCCAGGCAATCT
CCTTGCCACTCTCCTAGATCCAGTGTCACTGATGAGAATTGGCTGAGCCCCAGGCCAGCC
TCAGGACCCTCATCAAGGCCCACATCCCCCTGTGGGAAACGGAGGCACTCCAGTGCTGAA
GTTTGTTATGCTGGGTCCCTTTCACCCCATCACTCACCTGTTCCTTCACCTGGTCACTCC
CCCAGGGGAAGTGTGACAGAAGATACGTGGCTCAATGCTTCTGTCCATGGTGGGTCAGGC
CTTGGCCCTGCAGTTTTTCCATTTCAGTACTGTGTAGAGACTGACATCCCTCTCAAAACA
AGGAAAACTTCTGAAGATCAAGCTGCCATACTACCAGGAAAATTAGAGCTGTGTTCAGAT
GACCAAGGGAGTTTATCACCAGCCCGGGAGACTTCAATAGATGATGGCCTTGGATCTCAG
TATCCTTTAAAGAAAGATTCATGTGGTGATCAGTTTCTTTCAGTTCCTTCACCCTTTACC
TGGAGCAAACCAAAGCCTGGCCACACCCCTATATTTCGCACATCTTCATTACCTCCACTA
GACTGGCCTTTACCAGCTCATTTTGGACAATGTGAACTGAAAATAGAAGTGCAACCTAAA
ACTCATCATCGAGCCCATTATGAAACTGAAGGTAGCCGAGGGGCAGTAAAAGCATCTACT
GGGGGACATCCTGTTGTGAAGCTCCTGGGCTATAACGAAAAGCCAATAAATCTACAAATG
TTTATTGGGACAGCAGATGATCGATATTTACGACCTCATGCATTTTACCAGGTGCATCGA
ATCACTGGGAAGACAGTCGCTACTGCAAGCCAAGAGATAATAATTGCCAGTACAAAAGTT
CTGGAAATTCCACTTCTTCCTGAAAATAATATGTCAGCCAGTATTGATTGTGCAGGTATT
TTGAAACTCCGCAATTCAGATATAGAACTTCGAAAAGGAGAAACTGATATTGGCAGAAAG
AATACTAGAGTACGACTTGTGTTTCGTGTACACATCCCACAGCCCAGTGGAAAAGTCCTT
TCTCTGCAGATAGCCTCTATACCCGTTGAGTGCTCCCAGCGGTCTGCTCAAGAACTTCCT
CATATTGAGAAGTACAGTATCAACAGTTGTTCTGTAAATGGAGGTCATGAAATGGTTGTG
ACTGGATCTAATTTTCTTCCAGAATCCAAAATCATTTTTCTTGAAAAAGGACAAGATGGA
CGACCTCAGTGGGAGGTAGAAGGGAAGATAATCAGGGAAAAATGTCAAGGGGCTCACATT
GTCCTTGAAGTTCCTCCATATCATAACCCAGCAGTTACAGCTGCAGTGCAGGTGCACTTT
TATCTTTGCAATGGCAAGAGGAAAAAAAGCCAGTCTCAACGTTTTACTTATACACCAGTT
TTGATGAAGCAAGAACACAGAGAAGAGATTGATTTGTCTTCAGTTCCATCTTTGCCTGTG
CCTCATCCTGCTCAGACCCAGAGGCCTTCCTCTGATTCAGGGTGTTCACATGACAGTGTA
CTGTCAGGACAGAGAAGTTTGATTTGCTCCATCCCACAAACATATGCATCCATGGTGACC
TCATCCCATCTGCCACAGTTGCAGTGTAGAGATGAGAGTGTTAGTAAAGAACAGCATATG
ATTCCTTCTCCAATTGTACACCAGCCTTTTCAAGTCACACCAACACCTCCTGTGGGGTCT
TCCTATCAGCCTATGCAAACTAATGTTGTGTACAATGGACCAACTTGTCTTCCTATTAAT
GCTGCCTCTAGTCAAGAATTTGATTCAGTTTTGTTTCAGCAGGATGCAACTCTTTCTGGT
TTAGTGAATCTTGGCTGTCAACCACTGTCATCCATACCATTTCATTCTTCAAATTCAGGC
TCAACAGGACATCTCTTAGCCCATACACCTCATTCTGTGCATACCCTGCCTCATCTGCAA
TCAATGGGATATCATTGTTCAAATACAGGACAAAGATCTCTTTCTTCTCCAGTGGCTGAC
CAGATTACAGGTCAGCCTTCGTCTCAGTTACAACCTATTACATATGGTCCTTCACATTCA
GGGTCTGCTACAACAGCTTCCCCAGCAGCTTCTCATCCCTTGGCTAGTTCACCGCTTTCT
GGGCCACCATCTCCTCAGCTTCAGCCTATGCCTTACCAATCTCCTAGCTCAGGAACTGCC
TCATCACCGTCTCCAGCCACCAGAATGCATTCTGGACAGCACTCAACTCAAGCACAAAGT
ACGGGCCAGGGGGGTCTTTCTGCACCTTCATCCTTAATATGTCACAGTTTGTGTGATCCA
GCGTCATTTCCACCTGATGGGGCAACTGTGAGCATTAAACCTGAACCAGAAGATCGAGAG
CCTAACTTTGCAACCATTGGTCTGCAGGACATCACTTTAGATGATGTGAACGAGATAATT
GGGAGAGACATGTCCCAGATTTCTGTTTCCCAAGGAGCAGGGGTGAGCAGGCAGGCTCCC
CTCCCGAGTCCTGAGTCCCTGGATTTAGGAAGATCTGATGGGCTCTAA
Protein Properties
Number of Residues 1075
Molecular Weight 115592.8
Theoretical pI 6.35
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Nuclear factor of activated T-cells, cytoplasmic 3
MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL
CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC
HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS
SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS
PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS
PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD
DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL
DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM
FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI
LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP
HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI
VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV
PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM
IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG
LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD
QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA
SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE
PNFATIGLQDITLDDVNEIIGRDMSQISVSQGAGVSRQAPLPSPESLDLGRSDGL
GenBank ID Protein 27886561
UniProtKB/Swiss-Prot ID Q12968
UniProtKB/Swiss-Prot Entry Name NFAC3_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_173165.2
GeneCard ID NFATC3
GenAtlas ID NFATC3
HGNC ID HGNC:7777
References
General References Not Available