| Identification |
|---|
| HMDB Protein ID
| CDBP03009 |
| Secondary Accession Numbers
| Not Available |
| Name
| Mitochondrial intermediate peptidase |
| Description
| Not Available |
| Synonyms
|
- MIP
|
| Gene Name
| MIPEP |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in metalloendopeptidase activity |
| Specific Function
| Cleaves proteins, imported into the mitochondrion, to their mature size |
| GO Classification
|
| Function |
| hydrolase activity |
| metalloendopeptidase activity |
| peptidase activity |
| peptidase activity, acting on l-amino acid peptides |
| endopeptidase activity |
| catalytic activity |
| Process |
| metabolic process |
| macromolecule metabolic process |
| protein metabolic process |
| proteolysis |
|
| Cellular Location
|
- Mitochondrion matrix
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 13q12 |
| SNPs
| MIPEP |
| Gene Sequence
|
>2142 bp
ATGCTGTGCGTCGGAAGGCTGGGCGGCTTGGGAGCCAGAGCAGCAGCTCTGCCGCCCCGC
CGGGCGGGCCGGGGAAGCCTCGAAGCCGGGATCCGGGCCCGAAGGGTCAGCACCAGCTGG
TCTCCCGTGGGCGCCGCCTTCAATGTCAAGCCCCAGGGCAGCCGCTTGGACCTGTTCGGC
GAGCGCCGGGGTCTTTTTGGAGTTCCTGAGCTGAGTGCCCCAGAAGGATTTCATATTGCA
CAAGAAAAAGCCTTGAGAAAGACAGAATTGCTTGTGGACCGTGCATGTTCCACCCCACCT
GGGCCCCAGACCGTGCTGATCTTCGATGAGCTCTCGGATTCCTTATGCAGAGTGGCCGAC
TTGGCTGATTTTGTGAAAATCGCTCACCCTGAGCCAGCATTCAGAGAAGCTGCGGAAGAA
GCTTGTAGAAGTATTGGCACCATGGTAGAGAAGTTGAACACAAATGTGGATTTATATCAA
AGTTTGCAAAAATTACTAGCTGATAAAAAACTTGTGGATTCCCTTGATCCAGAAACAAGG
CGAGTGGCTGAACTGTTTATGTTTGATTTTGAAATTAGTGGAATCCATCTAGACAAAGAA
AAGCGTAAAAGAGCAGTGGACCTCAATGTTAAAATCTTGGATTTGAGTAGTACATTTCTT
ATGGGAACCAATTTTCCCAACAAGATTGAGAAGCATCTCTTACCAGAACACATTCGTCGT
AACTTTACATCTGCTGGGGATCATATCATAATTGATGGTCTCCACGCAGAATCACCAGAT
GACTTGGTGCGAGAAGCTGCTTATAAAATTTTTCTTTATCCCAATGCTGGTCAATTGAAA
TGTTTAGAAGAATTGCTCAGCAGCAGAGATCTTCTGGCAAAGTTGGTGGGGTATTCCACG
TTTTCTCACAGGGCTCTCCAAGGAACGATAGCTAAAAATCCAGAGACTGTCATGCAGTTC
CTTGAAAAACTATCTGACAAACTTTCTGAAAGAACTCTGAAAGATTTTGAGATGATACGA
GGGATGAAAATGAAACTGAATCCTCAAAATTCCGAAGTAATGCCCTGGGACCCCCCTTAC
TACAGTGGTGTGATTCGTGCAGAAAGGTATAATATTGAGCCCAGCCTATATTGCCCGTTT
TTCTCTCTTGGAGCATGCATGGAAGGCCTGAATATTTTGCTTAACAGACTGTTGGGGATT
TCATTATATGCAGAGCAGCCTGCAAAAGGAGAGGTGTGGAGCGAAGATGTCCGAAAACTG
GCTGTTGTTCATGAATCTGAAGGATTGTTGGGGTACATTTACTGTGATTTTTTTCAGCGA
GCAGACAAACCACATCAGGATTGCCATTTCACTATCCGTGGAGGCAGACTAAAGGAAGAT
GGAGACTATCAACTCCCAGTTGTAGTTCTTATGCTGAATCTTCCCCGTTCCTCAAGGAGT
TCTCCAACTTTGCTAACTCCTGGCATGATGGAAAATCTTTTCCATGAAATGGGACATGCC
ATGCATTCAATGCTAGGACGTACTCGTTACCAACACGTCACTGGGACCAGGTGCCCTACT
GATTTTGCTGAGGTTCCTTCTATTCTGATGGAGTACTTTGCAAATGATTATCGAGTAGTT
AACCAATTTGCCAGACATTATCAGACTGGACAGCCACTGCCAAAAAATATGGTGTCTCGT
CTTTGTGAATCTAAAAAGGTTTGTGCTGCAGCTGATATGCAACTTCAGGTCTTTTATGCC
ACTCTGGATCAAATCTACCATGGGAAGCATCCCCTGAGGAATTCAACCACAGACATTCTC
AAGGAAACACAAGAGAAATTCTATGGCCTACCATATGTTCCAAATACTGCCTGGCAGCTG
CGATTCAGCCACCTCGTGGGGTATGGTGCTAGATATTACTCTTACCTCATGTCCAGAGCG
GTCGCCTCCATGGTTTGGAAGGAGTGTTTTCTACAGGATCCTTTCAACAGGGCTGCCGGG
GAGCGCTATCGCAGGGAGATGCTGGCCCACGGTGGAGGCAGGGAGCCCATGCTCATGGTT
GAAGGTATGCTTCAGAAGTGTCCTTCTGTTGATGACTTCGTAAGTGCCCTCGTTTCCGAC
TTGGATCTGGACTTCGAAACTTTCCTCATGGATTCTGAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 713 |
| Molecular Weight
| 80639.9 |
| Theoretical pI
| 7.04 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Mitochondrial intermediate peptidase
MLCVGRLGGLGARAAALPPRRAGRGSLEAGIRARRVSTSWSPVGAAFNVKPQGSRLDLFG
ERRGLFGVPELSAPEGFHIAQEKALRKTELLVDRACSTPPGPQTVLIFDELSDSLCRVAD
LADFVKIAHPEPAFREAAEEACRSIGTMVEKLNTNVDLYQSLQKLLADKKLVDSLDPETR
RVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDLSSTFLMGTNFPNKIEKHLLPEHIRR
NFTSAGDHIIIDGLHAESPDDLVREAAYKIFLYPNAGQLKCLEELLSSRDLLAKLVGYST
FSHRALQGTIAKNPETVMQFLEKLSDKLSERTLKDFEMIRGMKMKLNPQNSEVMPWDPPY
YSGVIRAERYNIEPSLYCPFFSLGACMEGLNILLNRLLGISLYAEQPAKGEVWSEDVRKL
AVVHESEGLLGYIYCDFFQRADKPHQDCHFTIRGGRLKEDGDYQLPVVVLMLNLPRSSRS
SPTLLTPSMMENLFHEMGHAMHSMLGRTRYQHVTGTRCPTDFAEVPSILMEYFANDYRVV
NQFARHYQTGQPLPKNMVSRLCESKKVCAAADMQLQVFYATLDQIYHGKHPLRNSTTDIL
KETQEKFYGLPYVPNTAWQLRFSHLVGYGARYYSYLMSRAVASMVWKECFLQDPFNRAAG
ERYRREMLAHGGGREPMLMVEGMLQKCPSVDDFVSALVSDLDLDFETFLMDSE
|
| External Links |
|---|
| GenBank ID Protein
| 158257278 |
| UniProtKB/Swiss-Prot ID
| Q99797 |
| UniProtKB/Swiss-Prot Entry Name
| MIPEP_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK291923 |
| GeneCard ID
| MIPEP |
| GenAtlas ID
| MIPEP |
| HGNC ID
| HGNC:7104 |
| References |
|---|
| General References
| Not Available |