Showing Protein Multiple coagulation factor deficiency protein 2 (CDBP03004)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03004
Secondary Accession Numbers Not Available
Name Multiple coagulation factor deficiency protein 2
Description Not Available
Synonyms
  1. Neural stem cell-derived neuronal survival protein
Gene Name MCFD2
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. Plays a role in the secretion of coagulation factors
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Cellular Location
  1. Golgi apparatus
  2. Endoplasmic reticulum
  3. Endoplasmic reticulum-Golgi intermediate compartment
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 2p21
SNPs MCFD2
Gene Sequence 
>441 bp
ATGACCATGAGATCCCTGCTCAGAACCCCCTTCCTGTGTGGCCTGCTCTGGGCCTTTTGT
GCCCCAGGCGCCAGGGCTGAGGAGCCTGCAGCCAGCTTCTCCCAACCCGGCAGCATGGGC
CTGGATAAGAACACAGTGCACGACCAAGAGCATATCATGGAGCATCTAGAAGGTGTCATC
AACAAACCAGAGGCGGAGATGTCGCCACAAGAATTGCAGCTCCATTACTTCAAAATGCAT
GATTATGATGGCAATAATTTGCTTGATGGCTTAGAACTCTCCACAGCCATCACTCATGTC
CATAAGGAGGAAGGGAGTGAACAGGCACCACTAATGAGTGAAGATGAACTGATTAACATA
ATAGATGGTGTTTTGAGAGATGATGACAAGAACAATGATGGATACATTGACTATGCTGAA
TTTGCAAAATCACTGCAGTAG
Protein Properties
Number of Residues 146
Molecular Weight 16390.2
Theoretical pI 4.25
Pfam Domain Function Not Available
Signals
  • ["1-26"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Multiple coagulation factor deficiency protein 2
MTMRSLLRTPFLCGLLWAFCAPGARAEEPAASFSQPGSMGLDKNTVHDQEHIMEHLEGVI
NKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINI
IDGVLRDDDKNNDGYIDYAEFAKSLQ
GenBank ID Protein 62822465
UniProtKB/Swiss-Prot ID Q8NI22
UniProtKB/Swiss-Prot Entry Name MCFD2_HUMAN
PDB IDs Not Available
GenBank Gene ID AC016722
GeneCard ID MCFD2
GenAtlas ID MCFD2
HGNC ID HGNC:18451
References
General References Not Available