| Identification |
|---|
| HMDB Protein ID
| CDBP02993 |
| Secondary Accession Numbers
| Not Available |
| Name
| Liprin-beta-1 |
| Description
| Not Available |
| Synonyms
|
- PTPRF-interacting protein-binding protein 1
- Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1
- hSGT2
|
| Gene Name
| PPFIBP1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Replication, recombination and repair |
| Specific Function
| May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 12p12.1 |
| SNPs
| PPFIBP1 |
| Gene Sequence
|
>3036 bp
ATGATGAGTGATGCAAGTGACATGTTGGCTGCAGCGTTGGAGCAGATGGATGGTATCATA
GCAGGTTCTAAGGCTCTGGAATATTCCAATGGGATTTTTGATTGCCAATCTCCCACCTCT
CCATTCATGGGAAGTTTGCGAGCTCTGCACCTTGTGGAAGACCTGCGTGGATTGTTAGAG
ATGATGGAAACAGATGAGAAAGAAGGCTTGAGATGCCAGATCCCAGATTCAACAGCAGAA
ACGCTTGTTGAATGGCTTCAGAGTCAAATGACAAATGGACACCTACCAGGGAACGGAGAT
GTGTATCAAGAAAGGCTGGCACGTTTAGAAAATGATAAAGAATCCCTCGTTCTTCAGGTA
AGTGTGTTAACAGACCAGGTGGAGGCTCAGGGAGAGAAGATTCGAGATTTGGAGTTTTGT
CTTGAAGAGCACAGAGAGAAGTTGAATGCCACAGAAGAAATGCTGCAGCAGGAGCTTCTA
AGTAGGACATCCTTAGAAACTCAGAAGTTGGATCTGATGGCTGAAATATCTAACTTGAAG
TTGAAACTGACAGCTGTAGAGAAGGACAGATTGGATTATGAAGATAAGTTCAGAGACACA
GAGGGGCTGATTCAGGAGATCAATGATTTGAGGTTAAAAGTTAGTGAAATGGACAGTGAG
AGACTTCAGTATGAAAAAAAGCTTAAATCAACCAAATCTTTAATGGCCAAACTTTCTAGC
ATGAAAATCAAGGTGGGTCAGATGCAGTATGAAAAGCAGCGGATGGAACAAAAATGGGAG
TCACTGAAGGATGAACTGGCATCTTTAAAAGAACAACTAGAAGAAAAGGAATCTGAAGTA
AAAAGGCTACAAGAAAAATTGGTTTGCAAGATGAAAGGAGAAGGGGTTGAAATTGTTGAT
AGAGACATCGAAGTACAAAAAATGAAAAAAGCTGTGGAGTCCTTGATGGCAGCAAATGAA
GAAAAGGATCGGAAAATAGAAGATCTTCGACAGTGCCTGAACAGGTACAAGAAAATGCAA
GACACGGTGGTACTGGCCCAAGGCAAAGATGGAGAATATGAAGAGCTGCTCAATTCCAGT
TCCATCTCCTCTTTGCTGGATGCACAGGGTTTCAGTGATCTGGAGAAAAGTCCATCACCC
ACTCCAGTAATGGGATCTCCCAGTTGTGACCCATTTAACACAAGTGTTCCCGAAGAGTTC
CATACTACCATCTTGCAAGTTTCCATCCCTTCATTATTGCCAGCAACTGTAAGCATGGAA
ACTTCTGAAAAATCAAAGTTGACTCCTAAGCCAGAGACTTCATTTGAAGAAAATGATGGA
AACATAATCCTTGGTGCCACTGTTGATACCCAACTGTGTGATAAACTTTTAACTTCAAGT
CTGCAGAAGTCCAGCAGCCTGGGCAATCTGAAGAAAGAGACATCTGATGGGGAAAAGGAA
ACTATTCAGAAGACTTCAGAGGACAGAGCTCCGGCAGAAAGCAGGCCATTTGGGACCCTT
CCTCCCAGGCCCCCAGGGCAGGACACCTCCATGGATGACAACCCCTTCGGCACTCGAAAA
GTCAGATCTTCCTTTGGCCGGGGCTTTTTTAAAATCAAAAGTAACAAGAGAACAGCAAGT
GCACCAAACTTAGCTGAAACAGAAAAAGAGACAGCAGAGCACCTAGATCTGGCTGGTGCT
TCTTCTCGGCCAAAAGATTCACAGAGGAACAGTCCCTTCCAGATACCGCCTCCATCTCCA
GATTCCAAAAAGAAATCCAGAGGTATCATGAAACTCTTTGGAAAACTTAGGAGAAGTCAA
TCAACTACATTCAACCCAGATGACATGTCTGAGCCTGAATTCAAAAGAGGAGGGACAAGG
GCAACCGCGGGGCCCCGATTAGGTTGGTCTCGAGACTTGGGACAGTCTAACAGTGACTTG
GATATGCCATTTGCCAAGTGGACCAAGGAGCAGGTTTGCAATTGGCTGATGGAACAGGGC
TTGGGCTCGTACCTGAATTCTGGCAAGCACTGGATTGCATCTGGCCAAACGCTTTTGCAG
GCTTCTCAACAAGATCTAGAGAAGGAACTTGGAATCAAGCATTCACTTCATCGAAAGAAA
CTCCAGCTAGCACTCCAAGCCCTGGGATCTGAAGAAGAAACCAATCATGGGAAGCTGGAT
TTCAACTGGGTCACTAGATGGTTGGATGACATTGGCCTCCCTCAATATAAGACCCAGTTT
GATGAAGGACGGGTTGATGGTCGAATGCTACATTACATGACTGTTGATGACTTACTGTCT
CTGAAGGTTGTAAGTGTGCTACACCATCTCAGTATCAAAAGGGCCATCCAGGTCCTGAGG
ATCAATAACTTTGAACCAAACTGTCTACGGAGGCGGCCATCTGATGAGAATACCATCGCC
CCATCAGAAGTTCAGAAGTGGACTAACCATCGAGTGATGGAGTGGCTGCGCTCCGTGGAC
TTGGCAGAATATGCGCCCAATCTCAGAGGCAGTGGTGTCCATGGTGGGCTCATGGTTCTA
GAGCCTCGTTTTAACGTAGAAACAATGGCTCAGTTATTGAACATCCCACCCAATAAGACT
TTGCTGCGAAGACATTTGGCCACTCATTTCAACCTTCTGATTGGGGCTGAGGCACAGCAC
CAGAAGCGAGATGCCATGGAGCTGCCGGATTATGTACTTCTAACAGCTACTGCCAAAGTG
AAGCCAAAGAAACTTGCCTTTAGCAATTTTGGGAATTTGAGAAAGAAGAAACAGGAAGAT
GGTGAAGAATATGTTTGTCCAATGGAATTGGGACAGGCATCAGGAAGTGCATCTAAGAAA
GGATTTAAACCTGGTTTGGATATGCGCCTGTATGAGGAAGATGATTTGGACCGGTTAGAG
CAGATGGAAGATTCAGAAGGGACAGTGAGACAGATAGGTGCATTCTCTGAAGGCATCAAC
AATCTGACGCACATGTTAAAAGAAGATGACATGTTTAAAGATTTTGCTGCCCGTTCCCCC
AGTGCCAGCATTACAGATGAAGACTCAAACGTTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 1011 |
| Molecular Weight
| 114023.1 |
| Theoretical pI
| 5.22 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Liprin-beta-1
MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLK
LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
RDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSS
SISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSME
TSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKE
TIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTAS
APNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQ
STTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQG
LGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLD
FNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLR
INNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVL
EPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKV
KPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLE
QMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
|
| External Links |
|---|
| GenBank ID Protein
| 312032469 |
| UniProtKB/Swiss-Prot ID
| Q86W92 |
| UniProtKB/Swiss-Prot Entry Name
| LIPB1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_177444.2 |
| GeneCard ID
| PPFIBP1 |
| GenAtlas ID
| PPFIBP1 |
| HGNC ID
| HGNC:9249 |
| References |
|---|
| General References
| Not Available |