| Identification |
|---|
| HMDB Protein ID
| CDBP02983 |
| Secondary Accession Numbers
| Not Available |
| Name
| Lethal(2) giant larvae protein homolog 2 |
| Description
| Not Available |
| Synonyms
|
- HGL
|
| Gene Name
| LLGL2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein binding |
| Specific Function
| Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17q25.1 |
| SNPs
| LLGL2 |
| Gene Sequence
|
>3063 bp
ATGAGGCGGTTCCTGAGGCCAGGGCATGACCCTGTGCGGGAGAGGCTCAAGCGGGACCTG
TTCCAGTTTAACAAGACGGTGGAGCATGGCTTCCCGCACCAGCCCAGCGCCCTCGGCTAC
AGCCCGTCCCTGCGCATCCTGGCCATCGGCACCCGTTCTGGAGCCATCAAGCTCTACGGA
GCCCCAGGCGTGGAGTTCATGGGGCTGCACCAGGAGAACAACGCTGTGACGCAGATCCAC
CTCCTGCCCGGCCAGTGCCAGCTGGTCACCCTGCTGGATGACAACAGCCTGCACCTTTGG
AGCCTGAAGGTCAAGGGCGGGGCATCGGAGCTGCAGGAGGATGAGAGCTTCACACTGCGT
GGACCCCCAGGGGCTGCCCCCAGTGCCACACAGATCACCGTGGTCCTGCCACATTCCTCC
TGCGAGCTGCTCTACCTGGGCACCGAGAGTGGCAACGTGTTTGTGGTGCAGCTGCCAGCT
TTTCGTGCGCTGGAGGACCGGACCATCAGCTCGGACGCGGTGCTGCAGCGGTTGCCAGAG
GAGGCCCGCCACCGGCGTGTGTTCGAGATGGTGGAGGCACTGCAGGAGCACCCTCGAGAC
CCCAACCAGATCCTGATCGGCTACAGCCGAGGCCTCGTTGTCATCTGGGACCTACAGGGC
AGCCGCGTGCTCTACCACTTCCTCAGCAGCCAGCAACTGGAGAACATCTGGTGGCAGCGG
GACGGCCGCCTGCTCGTCAGCTGTCACTCTGACGGCAGCTACTGCCAGTGGCCCGTGTCC
AGCGAAGCCCAGCAACCAGAGCCCCTCCGCAGCCTCGTGCCTTACGGTCCCTTTCCTTGC
AAAGCGATTACCAGAATCCTCTGGCTGACCACTAGGCAGGGGTTGCCCTTCACCATCTTC
CAGGGTGGCATGCCACGGGCCAGCTACGGGGACCGCCACTGCATCTCAGTGATCCACGAT
GGCCAGCAGACGGCCTTCGACTTCACCTCCCGTGTCATCGGCTTCACTGTCCTCACAGAG
GCAGACCCTGCAGCCACCTTTGACGACCCCTATGCCCTGGTGGTGCTGGCTGAGGAGGAG
CTGGTGGTGATTGACCTGCAGACAGCAGGCTGGCCACCGGTCCAGCTGCCCTACCTGGCT
TCTCTGCACTGTTCCGCCATCACCTGCTCTCACCACGTCTCCAACATCCCGCTGAAGCTG
TGGGAGCGGATCATTGCCGCCGGCAGCCGGCAGAACGCACACTTCTCCACCATGGAGTGG
CCAATTGATGGTGGCACCAGCCTGACCCCAGCCCCACCCCAGAGGGACCTGCTGCTCACA
GGGCACGAGGACGGCACGGTGCGGTTCTGGGATGCCTCGGGTGTCTGCCTGCGGCTGCTC
TACAAACTCAGCACTGTGCGCGTGTTCCTCACCGACACGGACCCCAACGAGAACTTCAGT
GCCCAGGGCGAGGACGAGTGGCCCCCACTCCGCAAGGTGGGCTCCTTTGACCCCTACAGT
GATGACCCCCGGCTGGGCATCCAGAAGATCTTCCTCTGCAAGTACAGCGGCTACCTGGCT
GTGGCAGGCACGGCAGGGCAGGTGCTGGTACTGGAACTGAATGACGAGGCAGCGGAGCAG
GCTGTGGAGCAGGTGGAGGCCGACCTGCTGCAGGACCAAGAGGGCTACCGCTGGAAGGGG
CACGAGCGCCTGGCAGCCCGCTCAGGGCCCGTGCGCTTTGAGCCTGGCTTTCAGCCCTTC
GTGTTGGTGCAGTGTCAGCCCCCGGCTGTGGTCACCTCCTTGGCCCTGCACTCTGAGTGG
CGGCTCGTGGCCTTCGGCACCAGCCATGGCTTTGGCCTCTTTGACCACCAGCAGCGGCGG
CAGGTCTTTGTTAAGTGCACACTGCACCCCAGTGACCAGCTGGCCTTGGAGGGCCCACTC
TCCCGCGTCAAGTCCCTCAAGAAGTCCTTGCGTCAGTCATTCCGCCGGATGCGTCGGAGC
CGGGTGTCCAGCCGGAAGCGGCACCCGGCTGGCCCCCCAGGAGAGGCACAGGAGGGGAGT
GCCAAGGCTGAGCGGCCAGGCCTCCAGAACATGGAGCTGGCGCCTGTGCAGCGCAAGATC
GAGGCTCGCTCGGCAGAGGACTCCTTCACAGGCTTCGTCCGGACCCTGTACTTTGCTGAC
ACCTACCTGAAGGACAGCTCCCGGCACTGCCCCTCGCTGTGGGCTGGCACCAATGGGGGC
ACCATCTATGCCTTCTCCCTGCGTGTGCCTCCCGCCGAGCGGAGAATGGATGAGCCTGTG
CGGGCAGAGCAGGCCAAGGAGATCCAGCTGATGCACCGGGCGCCGGTGGTGGGCATCCTG
GTGCTCGACGGACACAGCGTACCCCTTCCCGAGCCCCTCGAAGTGGCCCATGATCTGTCG
AAGAGCCCTGACATGCAGGGAAGCCACCAGCTGCTCGTCGTATCAGAGGAGCAGTTCAAG
GTGTTCACGCTGCCCAAGGTGAGTGCCAAGCTGAAGTTGAAGCTGACGGCCCTGGAGGGC
TCAAGAGTGCGGCGGGTCAGCGTGGCCCACTTCGGCAGTCGTCGAGCCGAGGACTACGGG
GAGCACCACCTGGCAGTCCTTACCAACCTGGGCGACATCCAGGTGGTCTCGCTGCCCCTG
CTCAAGCCCCAGGTGCGCTACAGCTGCATCCGCCGGGAGGACGTCAGTGGCATCGCCTCC
TGCGTCTTCACCAAATATGGCCAAGGCTTCTACCTGATCTCACCCTCGGAGTTTGAGCGC
TTCTCTCTCTCCACCAAGTGGCTGGTGGAGCCCCGGTGTCTGGTGGATTCAGCAGAAACC
AAGAACCACCGCCCTGGTAACGGTGCGGGCCCCAAGAAGGCCCCGAGCCGAGCCAGGAAC
TCAGGGACTCAGAGTGATGGCGAGGAGAAGCAGCCCGGCCTGGTGATGGAGCGCGCTCTG
CTCAGTGATGAGAGAGTCCTGAAGGAAATCCAGAGCACACTGGAGGGAGACCGCGGGAGC
GGCAACTGGCGTTCACATCGAGCCGCCGTGGGGTGCAGCCTCAGCAATGGCGGAGCAGAG
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 1020 |
| Molecular Weight
| 113447.0 |
| Theoretical pI
| 7.54 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Lethal(2) giant larvae protein homolog 2
MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYG
APGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLR
GPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPE
EARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQR
DGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIF
QGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDDPYALVVLAEEE
LVVIDLQTAGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEW
PIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNENFS
AQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQ
AVEQVEADLLQDQEGYRWKGHERLAARSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEW
RLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRS
RVSSRKRHPAGPPGEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFTGFVRTLYFAD
TYLKDSSRHCPSLWAGTNGGTIYAFSLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVGIL
VLDGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEG
SRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIAS
CVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARN
SGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNGGAE
|
| External Links |
|---|
| GenBank ID Protein
| 73427803 |
| UniProtKB/Swiss-Prot ID
| Q6P1M3 |
| UniProtKB/Swiss-Prot Entry Name
| L2GL2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001031803.1 |
| GeneCard ID
| LLGL2 |
| GenAtlas ID
| LLGL2 |
| HGNC ID
| HGNC:6629 |
| References |
|---|
| General References
| Not Available |