Showing Protein Kv channel-interacting protein 4 (CDBP02967)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP02967
Secondary Accession Numbers Not Available
Name Kv channel-interacting protein 4
Description Not Available
Synonyms
  1. A-type potassium channel modulatory protein 4
  2. Calsenilin-like protein
  3. KChIP4
  4. Potassium channel-interacting protein 4
Gene Name KCNIP4
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Probably modulates channels density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Cellular Location
  1. Cell membrane
  2. Peripheral membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:4
Locus 4p15.32
SNPs KCNIP4
Gene Sequence 
>753 bp
ATGAATGTGAGGAGGGTGGAAAGCATTTCGGCTCAGCTGGAGGAGGCCAGCTCTACAGGC
GGTTTCCTGTACGCTCAGAACAGCACCAAGCGCAGCATTAAAGAGCGGCTCATGAAGCTC
TTGCCCTGCTCAGCTGCCAAAACGTCGTCTCCTGCTATTCAAAACAGCGTGGAAGATGAA
CTGGAGATGGCCACCGTCAGGCATCGGCCTGAAGCCCTTGAGCTTCTGGAAGCCCAGAGC
AAATTTACCAAGAAAGAGCTTCAGATCCTTTACAGAGGATTTAAGAATGAATGCCCCAGT
GGTGTTGTTAATGAAGAAACCTTCAAAGAGATTTACTCGCAGTTCTTTCCACAGGGAGAC
TCTACAACATATGCACATTTTCTGTTCAATGCATTTGATACAGACCACAATGGAGCTGTG
AGTTTCGAGGATTTCATCAAAGGTCTTTCCATTTTGCTCCGGGGGACAGTACAAGAAAAA
CTCAATTGGGCATTTAATCTGTATGACATAAATAAAGATGGCTACATCACTAAAGAGGAA
ATGCTTGATATAATGAAAGCAATATACGATATGATGGGTAAATGTACATATCCTGTCCTC
AAAGAAGATGCTCCCAGACAACACGTTGAAACATTTTTTCAGAAAATGGACAAAAATAAA
GATGGGGTTGTTACCATAGATGAGTTCATTGAAAGCTGCCAAAAAGATGAAAACATAATG
CGCTCCATGCAGCTCTTTGAAAATGTGATTTAA
Protein Properties
Number of Residues 250
Molecular Weight 28728.4
Theoretical pI 4.86
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Kv channel-interacting protein 4
MNVRRVESISAQLEEASSTGGFLYAQNSTKRSIKERLMKLLPCSAAKTSSPAIQNSVEDE
LEMATVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGD
STTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEE
MLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIM
RSMQLFENVI
GenBank ID Protein 24586671
UniProtKB/Swiss-Prot ID Q6PIL6
UniProtKB/Swiss-Prot Entry Name KCIP4_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_025221.5
GeneCard ID KCNIP4
GenAtlas ID KCNIP4
HGNC ID HGNC:30083
References
General References Not Available