| Identification |
| HMDB Protein ID
| CDBP02964 |
| Secondary Accession Numbers
| Not Available |
| Name
| Calcium/calmodulin-dependent protein kinase type 1B |
| Description
| Not Available |
| Synonyms
|
- CaM kinase I beta
- CaM kinase IB
- CaM-KI beta
- CaMKI-beta
- Pregnancy up-regulated non-ubiquitously-expressed CaM kinase
|
| Gene Name
| PNCK |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in protein kinase activity |
| Specific Function
| Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1 |
| GO Classification
|
| Function |
| adenyl ribonucleotide binding |
| atp binding |
| protein kinase activity |
| protein serine/threonine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| phosphorylation |
|
| Cellular Location
|
- Nucleus
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| PNCK |
| Gene Sequence
|
>1083 bp
ATGTGGAGGCGTGTATGCGGTGGCCTCGCTGGGAGGCGTCCGTCTGGGGACATGCTGCTG
CTGAAGAAACACACGGAGGACATCAGCAGCGTCTACGAGATCCGCGAGAGGCTCGGCTCG
GGTGCCTTCTCCGAGGTGGTGCTGGCCCAGGAGCGGGGCTCCGCACACCTCGTGGCCCTC
AAGTGCATCCCCAAGAAGGCCCTCCGGGGCAAGGAGGCCCTGGTGGAGAACGAGATCGCA
GTGCTCCGTAGGATCAGTCACCCCAACATCGTCGCTCTGGAGGATGTCCACGAGAGCCCT
TCCCACCTCTACCTGGCCATGGAACTGGTGACGGGTGGCGAGCTGTTTGACCGCATCATG
GAGCGCGGCTCCTACACAGAGAAGGATGCCAGCCATCTGGTGGGTCAGGTCCTTGGCGCC
GTCTCCTACCTGCACAGCCTGGGGATCGTGCACCGGGACCTCAAGCCCGAAAACCTCCTG
TATGCCACGCCCTTTGAGGACTCGAAGATCATGGTCTCTGACTTTGGACTCTCCAAAATC
CAGGCTGGGAACATGCTAGGCACCGCCTGTGGGACCCCTGGATATGTGGCCCCAGAGCTC
TTGGAGCAGAAACCCTACGGGAAGGCCGTAGATGTGTGGGCCCTGGGCGTCATCTCCTAC
ATCCTGCTGTGTGGGTACCCCCCCTTCTACGACGAGAGCGACCCTGAGCTCTTCAGCCAG
ATCCTGAGGGCCAGCTATGAGTTTGACTCTCCTTTCTGGGATGACATCTCAGAATCAGCC
AAAGACTTCATCCGGCACCTTCTGGAGCGAGACCCCCAGAAGAGGTTCACCTGCCAACAG
GCCTTGCGGCACCTTTGGATCTCTGGGGACACAGCCTTCGACAGGGACATCTTAGGCTCT
GTCAGTGAGCAGATCCGGAAGAACTTTGCTCGGACACACTGGAAGCGAGCCTTCAATGCC
ACCTCGTTCCTGCGCCACATCCGGAAGCTGGGGCAGATCCCAGAGGGCGAGGGGGCCTCT
GAGCAGGGCATGGCCCGCCACAGCCACTCAGGCCTCCGTGCTGGCCAGCCCCCCAAGTGG
TGA
|
| Protein Properties |
| Number of Residues
| 343 |
| Molecular Weight
| 38499.5 |
| Theoretical pI
| 6.75 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Calcium/calmodulin-dependent protein kinase type 1B
MLLLKKHTEDISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVEN
EIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQV
LGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVA
PELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDIS
ESAKDFIRHLLERDPQKRFTCQQALRHLWISGDTAFDRDILGSVSEQIRKNFARTHWKRA
FNATSFLRHIRKLGQIPEGEGASEQGMARHSHSGLRAGQPPKW
|
| External Links |
| GenBank ID Protein
| 209364621 |
| UniProtKB/Swiss-Prot ID
| Q6P2M8 |
| UniProtKB/Swiss-Prot Entry Name
| KCC1B_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| PNCK |
| GenAtlas ID
| PNCK |
| HGNC ID
| HGNC:13415 |
| References |
| General References
| Not Available |