| Identification |
|---|
| HMDB Protein ID
| CDBP02963 |
| Secondary Accession Numbers
| Not Available |
| Name
| Junctional sarcoplasmic reticulum protein 1 |
| Description
| Not Available |
| Synonyms
|
- JP-45
- Junctional-face membrane protein of 45 kDa homolog
|
| Gene Name
| JSRP1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Translation, ribosomal structure and biogenesis |
| Specific Function
| May function as a regulator of the voltage-sensitive calcium channel CACNA1S. May regulate CACNA1S membrane targeting and activity. May function in excitation/contraction coupling in muscle cells |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Endoplasmic reticulum membrane
- Sarcoplasmic reticulum membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19p13.3 |
| SNPs
| JSRP1 |
| Gene Sequence
|
>996 bp
ATGTCCATGACAACCAGAGCCTGGGAGGAGCTGGATGGCGGCCTGGGCAGCTGCCAGGCC
CTGGAGGACCACTCTGCGCTGGCCGAGACCCAGGAGGACAGGGCTTCAGCGACACCCAGG
CTGGCCGACTCCGGCAGCGTGCCCCACGACTCTCAGGTGGCTGAAGGCCCCAGTGTGGAC
ACCAGGCCCAAGAAGATGGAAAAAGAGCCTGCCGCCAGGGGGACCCCAGGAACGGGGAAG
GAGAGGCTGAAAGCCGGAGCGAGCCCTCGGAGCGTCCCCGCGCGCAAGAAGGCGCAGACC
GCGCCGCCCCTGCAGCCGCCGCCGCCGCCCCCGGCCCTGAGCGAGGAGCTGCCCTGGGGA
GACCTGTCGCTCAACAAGTGCCTGGTGCTCGCCTCGCTGGTGGCGCTGCTGGGCTCGGCT
TTCCAGCTGTGCCGCGACGCCGTCCCTGGGGAGGCAGCACTCCAAGCACGTGTGCCCGAG
CCCTGGGTCCCGCCAAGCTCAGCCCCGAGGGAGCCATCGTCGCCCCTGCCTAAGTTCGAG
GCCCAGGCGCCTCCATCAGCGCCGCCTGCGCCCCGGGCCGAGGCAGAGGTCAGACCCAAG
ATTCCCGGGAGTCGGGAGGCTGCAGAGAACGACGAAGAGGAGCCCGGCGAGGCCACCGGA
GAGGCCGTCCGGGAGGACCGTGTGACCCTCGCAGACCGGGGACCCAAGGAGAGGCCTCGG
AGAGAGGGGAAGCCGCGGAAGGAGAAGCCGCGGAAGGAGGAGAGACCTAAGAAAGAGAGG
CCGCGGAAAGAGGAGAGGCCACGGGCCGCCAGGGAGCCCCGGGAAGCCCTACCCCAGCGC
TGGGAGTCACGCGAAGGGGGCCACCGGCCGTGGGCACGGGACTCCAGGGACGCCGAGCCC
AGGAAGAAGCAGGCCTGGGTGTCCCCGAGGCGTCCCGACGAGGAGCAGCGGCCTGGGAGT
CGCCAGAAGCTCCGCGCAGGCAAGGGGCGGGACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 331 |
| Molecular Weight
| 36318.3 |
| Theoretical pI
| 10.14 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Junctional sarcoplasmic reticulum protein 1
MSMTTRAWEELDGGLGSCQALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVD
TRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWG
DLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFE
AQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPR
REGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEP
RKKQAWVSPRRPDEEQRPGSRQKLRAGKGRD
|
| External Links |
|---|
| GenBank ID Protein
| 16552528 |
| UniProtKB/Swiss-Prot ID
| Q96MG2 |
| UniProtKB/Swiss-Prot Entry Name
| JSPR1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK056978 |
| GeneCard ID
| JSRP1 |
| GenAtlas ID
| JSRP1 |
| HGNC ID
| HGNC:24963 |
| References |
|---|
| General References
| Not Available |