Showing Protein Guanylyl cyclase-activating protein 2 (CDBP02938)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP02938
Secondary Accession Numbers Not Available
Name Guanylyl cyclase-activating protein 2
Description Not Available
Synonyms
  1. GCAP 2
  2. Guanylate cyclase activator 1B
Gene Name GUCA1B
Protein Type Enzyme
Biological Properties
General Function Involved in calcium ion binding
Specific Function Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low, and GC1 and GC2 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Cellular Location
  1. Cell membrane
Pathways
Gene Properties
Chromosome Location Chromosome:6
Locus 6p21.1
SNPs GUCA1B
Gene Sequence 
>603 bp
ATGGGGCAGGAGTTTAGCTGGGAGGAGGCGGAGGCAGCTGGCGAGATAGATGTGGCGGAG
CTCCAGGAGTGGTACAAGAAGTTTGTGATGGAGTGCCCCAGCGGCACACTCTTTATGCAT
GAGTTTAAGCGCTTCTTCAAGGTCACAGACGATGAGGAGGCCTCCCAGTATGTAGAGGGC
ATGTTCCGAGCCTTCGACAAGAATGGGGACAACACCATCGACTTCCTGGAGTACGTGGCA
GCTCTGAATCTCGTGCTGAGGGGCACCCTGGAGCACAAGCTGAAGTGGACATTCAAGATC
TATGATAAGGATGGCAATGGCTGCATCGACCGCCTGGAGCTACTCAACATTGTGGAGGGA
ATTTACCAGCTGAAGAAAGCCTGCCGGCGAGAGCTACAGACTGAGCAAGACCAGCTGCTC
ACACCCGAGGAGGTCGTGGACAGGATCTTCCTCCTGGTGGATGAGAATGGAGATGGCCAG
CTGTCTCTGAACGAGTTTGTTGAAGGTGCCCGTCGGGACAAGTGGGTGATGAAGATGCTG
CAGATGGACATGAATCCCAGCAGCTGGCTCGCTCAGCAGAGACGGAAAAGTGCCATGTTC
TGA
Protein Properties
Number of Residues 200
Molecular Weight 23419.5
Theoretical pI 4.47
Pfam Domain Function Not Available
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Guanylyl cyclase-activating protein 2
MGQEFSWEEAEAAGEIDVAELQEWYKKFVMECPSGTLFMHEFKRFFKVTDDEEASQYVEG
MFRAFDKNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDGNGCIDRLELLNIVEG
IYQLKKACRRELQTEQGQLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWVMKML
QMDMNPSSWLAQQRRKSAMF
GenBank ID Protein 5702369
UniProtKB/Swiss-Prot ID Q9UMX6
UniProtKB/Swiss-Prot Entry Name GUC1B_HUMAN
PDB IDs Not Available
GenBank Gene ID AF173229
GeneCard ID GUCA1B
GenAtlas ID GUCA1B
HGNC ID HGNC:4679
References
General References Not Available