Cannabis Compound Database: Showing Protein GC-rich sequence DNA-binding factor (CDBP02923)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP02923

Secondary Accession Numbers

Not Available

Name

GC-rich sequence DNA-binding factor

Description

Not Available

Synonyms

GCF
TCF-9
Transcription factor 9

Gene Name

TCF9

Protein Type

Transcription Factor

Biological Properties

General Function

Involved in DNA binding

Specific Function

Factor that represses transcription. It binds to the GC- rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters

GO Classification

Component
organelle
membrane-bounded organelle
intracellular membrane-bounded organelle
nucleus
Function
binding
nucleic acid binding
dna binding
sequence-specific dna binding transcription factor activity
Process
regulation of macromolecule metabolic process
regulation of gene expression
regulation of transcription
biological regulation
regulation of biological process
regulation of metabolic process

Cellular Location

Nucleus

Pathways

Not Available

Gene Properties

Chromosome Location

Not Available

Locus

Not Available

SNPs

TCF9

Gene Sequence

>2346 bp
ATGGCTCACAGGCCGAAAAGGACTTTTCGGCAGCGCGCGGCTGATTCCAGCGACAGCGAT
GGCGCCGAGGAGTCGCCTGCTGAGCCTGGGGCGCCGAGGGAACTTCCGGTCCCGGGTTCT
GCGGAGGAAGAGCCGCCCTCTGGAGGAGGCCGCGCGCAGGTGGCGGGACTGCCCCACCGG
GTTCGGGGCCCTCGTGGCCGGGGCCGGGTCTGGGCGAGCTCCCGGCGTGCCACCAAAGCG
GCTCCCCGCGCGGACGAAGGCTCAGAATCCAGAACCCTTGATGTGTCCACAGATGAAGAG
GATAAAATACATCACTCCTCAGAAAGTAAGGATGATCAGGGTTTGTCTTCTGACAGTTCT
AGCTCTCTTGGAGAAAAAGAACTTTCATCAACAGTTAAGATCCCAGATGCAGCTTTTATT
CAGGCAGCCCGCAGAAAACGTGAATTGGCCAGGGCCCAAGATGACTATATTTCTTTGGAT
GTACAACATACCTCCTCCATCTCTGGTATGAAGAGAGAGAGCGAAGATGACCCTGAGAGT
GAGCCTGATGACCATGAAAAGAGAATACCATTTACTCTAAGACCTCAAACACTTAGACAA
AGGATGGCTGAGGAATCAATAAGCAGAAATGAAGAAACAAGTGAAGAAAGTCAGGAAGAT
GAAAAGCAAGATACTTGGGAACAACAGCAAATGAGGAAAGCAGTTAAAATCATAGAGGAA
AGAGACATAGATCTTTCCTGTGGCAATGGATCTTCAAAAGTGAAGAAATTTGATACTTCC
ATTTCATTTCCGCCAGTAAATTTAGAAATTATAAAGAAGCAATTAAATACTAGATTAACA
TTACTACAGGAAACTCACCGCTCACACCTGAGGGAGTATGAAAAATACGTACAAGATGTC
AAAAGCTCAAAGAGTACCATCCAGAACCTAGAGAGTTCATCAAATCAAGCTCTAAATTGT
AAATTCTATAAAAGCATGAAAATTTATGTGGAAAATTTAATTGACTGCCTTAATGAAAAG
ATTATCAACATCCAAGAAATAGAATCATCCATGCATGCACTCCTTTTAAAACAAGCTATG
ACCTTTATGAAACGCAGGCAAGATGAATTAAAACATGAATCAACGTATTTACAACAGTTA
TCACGCAAAGATGAGACATCCACAAGTGGAAACTTCTCAGTAGATGAAAAAACTCAGTGG
ATTTTAGAAGAGATTGAATCTCGAAGGACAAAAAGAAGACAAGCAAGGGTGCTTTCTGGG
AATTGTAACCATCAGGAAGGAACATCTAGTGATGATGAACTGCCTTCAGCAGAGATGATT
GACTTCCAAAAAAGCCAAGGTGACATTTTACAGAAACAGAAGAAAGTTTTTGAAGAAGTG
CAAGATGATTTTTGTAACATCCAGAATATTTTGTTGAAATTTCAGCAATGGCGAGAAAAG
TTTCCTGACTCCTATTATGAAGCTTTCATTAGTTTATGCATACCAAAGCTTTTAAATCCC
CTAATACGAGTTCAGTTGATTGATTGGAATCCTCTTAAGTTGGAATCCACAGGTTTAAAA
GAGATGCCATGGTTCAAATCTGTAGAAGAATTTATGGATAGCAGTGTGGAAGATTCAAAG
AAGGAAAGTAGTTCAGATAAAAAAGTCTTGTCTGCAATCATCAACAAAACAATTATTCCC
CGACTTACAGACTTTGTAGAATTCCTTTGGGATCCTTTGTCAACCTCACAGACAACAAGT
TTAATAACACATTGCAGAGTGATTCTTGAAGAACATTCCACTTGTGAAAATGAAGTTAGT
AAAAGCAGACAGGATTTACTTAAATCCATTGTTTCAAGAATGAAAAAGGCAGTAGAAGAT
GATGTTTTTATTCCTCTGTATCCAAAGAGTGCTGTAGAAAACAAAACATCACCTCATTCA
AAGTTCCAAGAAAGACAGTTCTGGTCAGGCCTAAAGCTCTTCCGCAATATTCTTCTTTGG
AATGGACTCCTTACAGATGACACCTTGCAAGAACTAGGACTAGGGAAGCTGCTAAATCGT
TACCTTATTATAGCACTTCTCAATGCCACACCTGGGCCAGATGTGGTTAAAAAGTGCAAC
CAGGTAGCAGCATGTCTACCAGAAAAATGGTTTGAAAATTCTGCCATGAGGACATCTATT
CCACAGCTAGAAAACTTCATTCAGTTTTTATTGCAGTCTGCACATAAATTATCTAGAAGT
GAATTCAGGGATGAAGTCGAAGAAATAATTCTTATTTTGGTGAAAATAAAAGCTTTGAAT
CAAGCAGAATCCTTCATAGGAGAGCATCACCTAGACCATCTTAAATCACTAATTAAAGAA
GATTGA

Protein Properties

Number of Residues

781

Molecular Weight

89383.7

Theoretical pI

5.81

Pfam Domain Function

GCFC (PF07842 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>GC-rich sequence DNA-binding factor
MAHRPKRTFRQRAADSSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGRAQVAGLPHR
VRGPRGRGRVWASSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSS
SSLGEKELSSTVKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPES
EPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEE
RDIDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDV
KSSKSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAM
TFMKRRQDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSG
NCNHQEGTSSDDELPSAEMIDFQKSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREK
FPDSYYEAFISLCIPKLLNPLIRVQLIDWNPLKLESTGLKEMPWFKSVEEFMDSSVEDSK
KESSSDKKVLSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVILEEHSTCENEVS
KSRQDLLKSIVSRMKKAVEDDVFIPLYPKSAVENKTSPHSKFQERQFWSGLKLFRNILLW
NGLLTDDTLQELGLGKLLNRYLIIALLNATPGPDVVKKCNQVAACLPEKWFENSAMRTSI
PQLENFIQFLLQSAHKLSRSEFRDEVEEIILILVKIKALNQAESFIGEHHLDHLKSLIKE
D

External Links

GenBank ID Protein

62822425

UniProtKB/Swiss-Prot ID

P16383

UniProtKB/Swiss-Prot Entry Name

GCF_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AC005034

GeneCard ID