| Identification |
| HMDB Protein ID
| CDBP02899 |
| Secondary Accession Numbers
| Not Available |
| Name
| Alpha-2-HS-glycoprotein |
| Description
| Not Available |
| Synonyms
|
- Alpha-2-HS-glycoprotein chain A
- Alpha-2-HS-glycoprotein chain B
- Alpha-2-Z-globulin
- Ba-alpha-2-glycoprotein
- Fetuin-A
|
| Gene Name
| AHSG |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in cysteine-type endopeptidase inhibitor activity |
| Specific Function
| Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions |
| GO Classification
|
| Function |
| endopeptidase inhibitor activity |
| enzyme regulator activity |
| enzyme inhibitor activity |
| cysteine-type endopeptidase inhibitor activity |
| peptidase inhibitor activity |
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:3 |
| Locus
| 3q27 |
| SNPs
| AHSG |
| Gene Sequence
|
>1104 bp
ATGAAGTCCCTCGTCCTGCTCCTTTGTCTTGCTCAGCTCTGGGGCTGCCACTCAGCCCCA
CATGGCCCAGGGCTGATTTATAGACAACCGAACTGCGATGATCCAGAAACTGAGGAAGCA
GCTCTGGTGGCTATAGACTACATCAATCAAAACCTTCCTTGGGGATACAAACACACCTTG
AACCAGATTGATGAAGTAAAGGTGTGGCCTCAGCAGCCCTCCGGAGAGCTGTTTGAGATT
GAAATAGACACCCTGGAAACCACCTGCCATGTGCTGGACCCCACCCCTGTGGCAAGATGC
AGCGTGAGGCAGCTGAAGGAGCATGCTGTCGAAGGAGACTGTGATTTCCAGCTGTTGAAA
CTAGATGGCAAGTTTTCCGTGGTATACGCAAAATGTGATTCCAGTCCAGACTCAGCCGAG
GACGTGCGCAAGGTGTGCCAAGACTGCCCCCTGCTGGCCCCGCTGAACGACACCAGGGTG
GTGCACGCCGCGAAAGCTGCCCTGGCCGCCTTCAACGCTCAGAACAACGGCTCCAATTTT
CAGCTGGAGGAAATTTCCCGGGCTCAGCTTGTGCCCCTCCCACCTTCTACCTATGTGGAG
TTTACAGTGTCTGGCACTGACTGTGTTGCTAAAGAGGCCACAGAGGCAGCCAAGTGTAAC
CTGCTGGCAGAAAAGCAATATGGCTTTTGTAAGGCAACACTCAGTGAGAAGCTTGGTGGG
GCAGAGGTTGCAGTGACCTGCACGGTGTTCCAAACACAGCCCGTGACCTCACAGCCCCAA
CCAGAAGGTGCCAATGAAGCAGTCCCCACCCCCGTGGTGGACCCAGATGCACCTCCGTCC
CCTCCACTTGGCGCACCTGGACTCCCTCCAGCTGGCTCACCCCCAGACTCCCATGTGTTA
CTGGCAGCTCCTCCAGGACACCAGTTGCACCGGGCGCACTACGACCTGCGCCACACCTTC
ATGGGTGTGGTCTCATTGGGGTCACCCTCAGGAGAAGTGTCGCACCCCCGGAAAACACGC
ACAGTGGTGCAGCCTAGTGTTGGTGCTGCTGCTGGGCCAGTGGTTCCTCCATGTCCGGGG
AGGATCAGACACTTCAAGGTCTAG
|
| Protein Properties |
| Number of Residues
| 367 |
| Molecular Weight
| 39324.3 |
| Theoretical pI
| 5.52 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Alpha-2-HS-glycoprotein
MKSLVLLLCLAQLWGCHSAPHGPGLIYRQPNCDDPETEEAALVAIDYINQNLPWGYKHTL
NQIDEVKVWPQQPSGELFEIEIDTLETTCHVLDPTPVARCSVRQLKEHAVEGDCDFQLLK
LDGKFSVVYAKCDSSPDSAEDVRKVCQDCPLLAPLNDTRVVHAAKAALAAFNAQNNGSNF
QLEEISRAQLVPLPPSTYVEFTVSGTDCVAKEATEAAKCNLLAEKQYGFCKATLSEKLGG
AEVAVTCTVFQTQPVTSQPQPEGANEAVPTPVVDPDAPPSPPLGAPGLPPAGSPPDSHVL
LAAPPGHQLHRAHYDLRHTFMGVVSLGSPSGEVSHPRKTRTVVQPSVGAAAGPVVPPCPG
RIRHFKV
|
| External Links |
| GenBank ID Protein
| 7106502 |
| UniProtKB/Swiss-Prot ID
| P02765 |
| UniProtKB/Swiss-Prot Entry Name
| FETUA_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB038689 |
| GeneCard ID
| AHSG |
| GenAtlas ID
| AHSG |
| HGNC ID
| HGNC:349 |
| References |
| General References
| Not Available |