| Identification |
|---|
| HMDB Protein ID
| CDBP02887 |
| Secondary Accession Numbers
| Not Available |
| Name
| Extended synaptotagmin-2 |
| Description
| Not Available |
| Synonyms
|
- Chr2Syt
- E-Syt2
|
| Gene Name
| ESYT2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| May play a role as calcium-regulated intrinsic membrane protein |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cell membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7q36.3 |
| SNPs
| ESYT2 |
| Gene Sequence
|
>2766 bp
ATGACCGCAAACAGGGACGCCGCCCTCTCATCCCACCGCCACCCCGGCTGCGCTCAGCGG
CCGCGCACCCCCACGTTTGCCAGCAGCTCCCAGAGGCGGTCAGCCTTTGGGTTTGACGAC
GGCAACTTCCCGGGCCTCGGCGAGCGCAGCCACGCACCCGGAAGCCGCCTCGGGGCGCGA
CGCCGAGCCAAAACCGCCCGCGGGCTCCGAGGCCACAGGCAAAGGGGCGCTGGCGCGGGG
CTGAGCCGCCCGGGATCAGCGCGAGCACCCAGCCCGCCTCGGCCGGGAGGGCCTGAGAAC
CCCGGGGGCGTGCTGAGCGTGGAGCTGCCCGGGCTGCTGGCGCAGCTGGCGCGGAGCTTC
GCGCTGCTGCTGCCCGTGTACGCGCTGGGCTACCTGGGGCTCAGCTTCAGCTGGGTTCTC
CTCGCGCTCGCGCTGCTCGCCTGGTGTCGCCGCAGCCGCGGCCTCAAGGCCCTGCGCCTG
TGCCGCGCGCTGGCGCTGCTGGAAGACGAGGAGCGCGTCGTGCGCCTGGGGGTGCGCGCC
TGCGACCTGCCCGCCTGGGTTCATTTTCCAGACACTGAAAGAGCAGAATGGCTAAATAAG
ACTGTAAAACACATGTGGCCTTTCATTTGCCAATTTATAGAGAAGTTGTTTCGAGAAACT
ATAGAACCAGCCGTGCGGGGAGCAAACACCCACCTTAGCACCTTTAGTTTCACGAAGGTC
GACGTGGGCCAGCAGCCCCTCAGGATCAATGGTGTTAAGGTATACACTGAAAATGTAGAC
AAAAGGCAAATTATTTTGGACCTTCAGATTAGTTTTGTAGGAAATTGTGAGATTGATTTG
GAGATCAAACGATATTTTTGTAGAGCTGGTGTGAAAAGTATCCAGATTCATGGTACCATG
CGGGTGATCCTGGAACCGTTGATTGGAGATATGCCCTTAGTTGGAGCTTTGTCTATCTTC
TTCCTTAGGAAACCACTTTTAGAAATTAACTGGACAGGACTGACGAATCTTCTGGATGTC
CCTGGATTGAATGGTTTATCAGATACTATCATTTTGGATATAATATCAAACTATCTGGTG
CTTCCCAATCGAATCACCGTTCCACTTGTCAGTGAAGTTCAAATAGCTCAGTTGCGGTTT
CCTGTACCAAAGGGTGTTCTAAGGATACATTTTATTGAAGCTCAGGATCTTCAGGGGAAA
GACACTTACCTTAAGGGACTTGTCAAGGGAAAGTCAGACCCCTATGGAATCATTAGAGTT
GGCAACCAAATCTTCCAAAGCAGAGTCATCAAGGAGAACCTCAGTCCAAAGTGGAATGAA
GTCTATGAGGCTTTAGTGTATGAACATCCTGGACAAGAATTAGAGATTGAGCTCTTTGAT
GAAGACCCAGACAAGGATGACTTTTTAGGAAGTCTTATGATTGACCTCATTGAAGTTGAA
AAGGAGCGCCTTTTAGATGAATGGTTCACTCTGGACGAGGTTCCCAAGGGGAAGCTACAC
TTGAGACTGGAGTGGCTCACGTTAATGCCAAATGCGTCAAACCTCGACAAGGTGCTAACA
GACATCAAAGCTGACAAAGACCAAGCCAACGATGGTCTTTCCTCTGCATTGCTGATCTTG
TACTTGGATTCAGCAAGGAACCTTCCGTCAGGGAAGAAAATAAGCAGCAACCCAAATCCT
GTTGTCCAGATGTCAGTTGGGCACAAGGCCCAGGAGAGCAAGATTCGATACAAAACCAAT
GAACCTGTGTGGGAGGAAAACTTCACTTTCTTCATTCACAATCCCAAGCGCCAGGACCTT
GAAGTTGAGGTCAGAGACGAGCAGCACCAGTGTTCCCTGGGGAACCTGAAGGTCCCCCTC
AGCCAGCTGCTCACCAGTGAGGACATGACTGTGAGCCAGCGCTTCCAGCTCAGTAACTCG
GGTCCAAACAGCACCATCAAGATGAAGATTGCCCTGCGGGTGCTCCATCTCGAAAAGCGA
GAAAGGCCTCCAGACCACCAACACTCAGCTCAAGTCAAACGTCCCTCTGTGTCCAAAGAG
GGGAGGAAAACATCCATCAAATCTCATATGTCTGGGTCTCCAGGCCCTGGTGGCAGCAAC
ACAGCTCCATCCACACCAGTCATTGGGGGCAGTGATAAGCCTGGTATGGAAGAAAAGGCC
CAGCCCCCTGAGGCCGGCCCTCAGGGGCTGCACGACCTGGGCAGAAGCTCCTCCAGCCTC
CTGGCCTCCCCAGGCCACATCTCAGTCAAGGAGCCGACCCCCAGCATCGCCTCGGACATC
TCGCTGCCCATCGCCACCCAGGAGCTGCGGCAAAGGCTGAGGCAGCTGGAAAACGGGACG
ACCCTGGGACAGTCTCCACTGGGGCAGATCCAGCTGACCATCCGGCACAGCTCGCAGAGA
AACAAGCTTATCGTGGTCGTGCATGCCTGCAGAAACCTCATTGCCTTCTCTGAAGACGGC
TCTGACCCCTATGTCCGCATGTATTTATTACCAGACAAGAGGCGGTCAGGAAGGAGGAAA
ACACACGTGTCAAAGAAAACATTAAATCCAGTGTTTGATCAAAGCTTTGATTTCAGTGTT
TCGTTACCAGAAGTCCAGAGGAGAACGCTTGACGTTGCCGTGAAGAACAGTGGCGGCTTC
CTGTCCAAAGACAAAGGGCTCCTTGGCAAAGTATTGGTTGCTCTGGCATCTGAAGAACTT
GCCAAAGGCTGGACCCAGTGGTATGACCTCACGGAAGATGGGACGAGGCCTCAGGCGATG
ACATAG
|
| Protein Properties |
|---|
| Number of Residues
| 921 |
| Molecular Weight
| 102356.5 |
| Theoretical pI
| 9.8 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Extended synaptotagmin-2
MTANRDAALSSHRHPGCAQRPRTPTFASSSQRRSAFGFDDGNFPGLGERSHAPGSRLGAR
RRAKTARGLRGHRQRGAGAGLSRPGSARAPSPPRPGGPENPGGVLSVELPGLLAQLARSF
ALLLPVYALGYLGLSFSWVLLALALLAWCRRSRGLKALRLCRALALLEDEERVVRLGVRA
CDLPAWVHFPDTERAEWLNKTVKHMWPFICQFIEKLFRETIEPAVRGANTHLSTFSFTKV
DVGQQPLRINGVKVYTENVDKRQIILDLQISFVGNCEIDLEIKRYFCRAGVKSIQIHGTM
RVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTNLLDVPGLNGLSDTIILDIISNYLV
LPNRITVPLVSEVQIAQLRFPVPKGVLRIHFIEAQDLQGKDTYLKGLVKGKSDPYGIIRV
GNQIFQSRVIKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDKDDFLGSLMIDLIEVE
KERLLDEWFTLDEVPKGKLHLRLEWLTLMPNASNLDKVLTDIKADKDQANDGLSSALLIL
YLDSARNLPSGKKISSNPNPVVQMSVGHKAQESKIRYKTNEPVWEENFTFFIHNPKRQDL
EVEVRDEQHQCSLGNLKVPLSQLLTSEDMTVSQRFQLSNSGPNSTIKMKIALRVLHLEKR
ERPPDHQHSAQVKRPSVSKEGRKTSIKSHMSGSPGPGGSNTAPSTPVIGGSDKPGMEEKA
QPPEAGPQGLHDLGRSSSSLLASPGHISVKEPTPSIASDISLPIATQELRQRLRQLENGT
TLGQSPLGQIQLTIRHSSQRNKLIVVVHACRNLIAFSEDGSDPYVRMYLLPDKRRSGRRK
THVSKKTLNPVFDQSFDFSVSLPEVQRRTLDVAVKNSGGFLSKDKGLLGKVLVALASEEL
AKGWTQWYDLTEDGTRPQAMT
|
| External Links |
|---|
| GenBank ID Protein
| 116292891 |
| UniProtKB/Swiss-Prot ID
| A0FGR8 |
| UniProtKB/Swiss-Prot Entry Name
| ESYT2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| DQ993201 |
| GeneCard ID
| ESYT2 |
| GenAtlas ID
| ESYT2 |
| HGNC ID
| HGNC:22211 |
| References |
|---|
| General References
| Not Available |