| Identification |
|---|
| HMDB Protein ID
| CDBP02881 |
| Secondary Accession Numbers
| Not Available |
| Name
| EF-hand domain-containing protein 1 |
| Description
| Not Available |
| Synonyms
|
- Myoclonin-1
|
| Gene Name
| EFHC1 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| May enhance calcium influx through CACNA1E and stimulate programmed cell death |
| GO Classification
|
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:6 |
| Locus
| 6p12.3 |
| SNPs
| EFHC1 |
| Gene Sequence
|
>1923 bp
ATGGTGTCCAATCCCGTGCATGGCTTGCCCTTTCTTCCGGGCACGTCCTTTAAGGACTCT
ACGAAAACAGCCTTCCACAGAAGTCAGACGCTGAGCTACAGGAACGGCTATGCAATTGTT
CGACGTCCAACAGTTGGGATAGGCGGAGACCGGCTCCAGTTCAACCAGCTGTCCCAGGCT
GAGCTGGATGAGTTGGCCAGTAAGGCACCAGTCTTAACTTATGGCCAACCTAAACAAGCC
CCACCTGCGGATTTTATTCCTGCGCATGTGGCCTTTGACAAAAAGGTACTGAAATTTGAT
GCCTATTTCCAAGAAGATGTTCCTATGTCAACTGAGGAACAGTATAGGATCCGTCAGGTG
AACATTTACTATTATCTAGAAGATGACAGCATGTCTGTCATAGAGCCTGTTGTAGAAAAT
TCTGGAATCCTTCAAGGCAAGTTAATAAAACGCCAGCGGCTAGCCAAGAATGACCGGGGT
GACCATTACCATTGGAAAGACCTAAATCGAGGAATAAACATCACAATTTATGGCAAAACT
TTCCGCGTTGTTGACTGTGACCAATTCACACAGGTATTTTTAGAAAGCCAAGGAATTGAG
TTAAATCCACCAGAGAAGATGGCTCTTGATCCTTACACTGAACTCCGAAAACAGCCTCTT
CGTAAGTATGTCACCCCATCAGACTTTGATCAACTCAAGCAATTTCTCACCTTTGACAAA
CAGGTCCTTCGATTCTATGCAATCTGGGATGATACAGACAGCATGTATGGTGAATGTCGG
ACCTACATCATTCATTACTATCTTATGGATGATACGGTGGAAATTCGAGAGGTCCACGAA
CGGAATGATGGGAGAGATCCTTTCCCACTCCTAATGAACCGCCAGCGTGTGCCCAAAGTT
TTGGTGGAAAATGCAAAGAACTTCCCTCAGTGTGTGCTAGAAATCTCTGACCAAGAAGTG
TTGGAATGGTATACTGCTAAAGACTTCATTGTTGGGAAGTCACTCACTATCCTTGGGAGA
ACTTTCTTCATTTATGATTGTGATCCATTTACTCGACGGTATTACAAAGAGAAGTTTGGA
ATCACTGATTTACCACGTATTGATGTGAGCAAGCGGGAACCACCTCCAGTAAAACAGGAG
TTGCCTCCTTATAACGGTTTTGGACTAGTGGAAGATTCTGCTCAGAATTGTTTTACTCTC
ATTCCAAAAGCTCCAAAAAAAGACGTTATTAAAATGCTGGTGAATGATAACAAGGTGCTT
CGTTATTTGGCTGTACTGGAATCCCCCATCCCAGAAGACAAAGACCGCAGATTTGTCTTC
TCTTACTTTCTAGCTACCGACATGATCAGTATCTTTGAGCCTCCTGTTCGCAATTCTGGT
ATCATTGGGGGCAAGTACCTTGGCAGGACTAAAGTTGTTAAACCATACTCTACAGTGGAC
AACCCTGTCTACTATGGCCCCAGTGACTTCTTCATTGGTGCTGTGATTGAAGTGTTTGGT
CACCGGTTCATCATCCTTGATACAGACGAGTATGTTTTGAAATACATGGAGAGCAACGCT
GCCCAGTATTCACCAGAAGCACTCGCGTCAATTCAGAACCATGTCCGAAAGCGAGAAGCG
CCTGCTCCAGAAGCAGAAAGCAAGCAAACTGAAAAGGATCCAGGCGTGCAGGAATTGGAA
GCATTAATAGACACAATTCAGAAGCAACTGAAAGATCACTCATGCAAAGACAACATTCGT
GAGGCATTTCAAATTTATGACAAGGAAGCTTCAGGATATGTGGACAGAGACATGTTCTTT
AAAATCTGTGAATCGCTTAACGTCCCAGTGGATGACTCCTTGGTTAAGGAGTTAATCAGG
ATGTGCTCTCATGGAGAAGGCAAAATTAACTACTATAACTTTGTTCGTGCTTTCTCAAAC
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 640 |
| Molecular Weight
| 73989.7 |
| Theoretical pI
| 6.04 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>EF-hand domain-containing protein 1
MVSNPVHGLPFLPGTSFKDSTKTAFHRSQTLSYRNGYAIVRRPTVGIGGDRLQFNQLSQA
ELDELASKAPVLTYGQPKQAPPADFIPAHVAFDKKVLKFDAYFQEDVPMSTEEQYRIRQV
NIYYYLEDDSMSVIEPVVENSGILQGKLIKRQRLAKNDRGDHYHWKDLNRGINITIYGKT
FRVVDCDQFTQVFLESQGIELNPPEKMALDPYTELRKQPLRKYVTPSDFDQLKQFLTFDK
QVLRFYAIWDDTDSMYGECRTYIIHYYLMDDTVEIREVHERNDGRDPFPLLMNRQRVPKV
LVENAKNFPQCVLEISDQEVLEWYTAKDFIVGKSLTILGRTFFIYDCDPFTRRYYKEKFG
ITDLPRIDVSKREPPPVKQELPPYNGFGLVEDSAQNCFALIPKAPKKDVIKMLVNDNKVL
RYLAVLESPIPEDKDRRFVFSYFLATDMISIFEPPVRNSGIIGGKYLGRTKVVKPYSTVD
NPVYYGPSDFFIGAVIEVFGHRFIILDTDEYVLKYMESNAAQYSPEALASIQNHVRKREA
PAPEAESKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFF
KICESLNVPVDDSLVKELIRMCSHGEGKINYYNFVRAFSN
|
| External Links |
|---|
| GenBank ID Protein
| 7022518 |
| UniProtKB/Swiss-Prot ID
| Q5JVL4 |
| UniProtKB/Swiss-Prot Entry Name
| EFHC1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK001328 |
| GeneCard ID
| EFHC1 |
| GenAtlas ID
| EFHC1 |
| HGNC ID
| HGNC:16406 |
| References |
|---|
| General References
| Not Available |