| Identification |
|---|
| HMDB Protein ID
| CDBP02861 |
| Secondary Accession Numbers
| Not Available |
| Name
| Calcyclin-binding protein |
| Description
| Not Available |
| Synonyms
|
- CacyBP
- S100A6-binding protein
- Siah-interacting protein
- hCacyBP
|
| Gene Name
| CACYBP |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein homodimerization activity |
| Specific Function
| May be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1) |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Nucleus
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q24-q25 |
| SNPs
| CACYBP |
| Gene Sequence
|
>687 bp
ATGGCTTCAGAAGAGCTACAGAAAGATCTAGAAGAGGTAAAGGTGTTGCTGGAAAAGGCT
ACTAGGAAAAGAGTACGTGATGCCCTTACAGCTGAAAAATCCAAGATTGAGACAGAAATC
AAGAACAAGATGCAACAGAAATCACAGAAGAAAGCAGAACTTCTTGATAATGAAAAACCA
GCTGCTGTGGTTGCTCCCATTACAACGGGCTATACGGTGAAAATCAGTAATTATGGATGG
GATCAGTCAGATAAGTTTGTGAAAATCTACATTACCTTAACTGGAGTTCATCAAGTTCCC
ACTGAGAATGTGCAGGTGCATTTCACAGAGAGGTCATTTGATCTTTTGGTAAAGAATCTA
AATGGGAAGAGTTACTCCATGATTGTGAACAATCTCTTGAAACCCATCTCTGTGGAAGGC
AGTTCAAAAAAAGTCAAGACTGATACAGTTCTTATATTGTGTAGAAAGAAAGTGGAAAAC
ACAAGGTGGGATTACCTGACCCAGGTTGAAAAGGAGTGCAAAGAAAAAGAGAAGCCCTCC
TATGACACTGAAACAGATCCTAGTGAGGGATTGATGAATGTTCTAAAGAAAATTTATGAA
GATGGAGACGATGATATGAAGCGAACCATTAATAAAGCCTGGGTGGAATCAAGAGAGAAG
CAAGCCAAAGGAGACACGGAATTTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 228 |
| Molecular Weight
| 26209.8 |
| Theoretical pI
| 8.59 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Calcyclin-binding protein
MASEELQKDLEEVKVLLEKATRKRVRDALTAEKSKIETEIKNKMQQKSQKKAELLDNEKP
AAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTENVQVHFTERSFDLLVKNL
NGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRWDYLTQVEKECKEKEKPS
YDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAKGDTEF
|
| External Links |
|---|
| GenBank ID Protein
| 3063653 |
| UniProtKB/Swiss-Prot ID
| Q9HB71 |
| UniProtKB/Swiss-Prot Entry Name
| CYBP_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF057356 |
| GeneCard ID
| CACYBP |
| GenAtlas ID
| CACYBP |
| HGNC ID
| HGNC:30423 |
| References |
|---|
| General References
| Not Available |