Showing Protein C-X-C motif chemokine 11 (CDBP02859)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP02859
Secondary Accession Numbers Not Available
Name C-X-C motif chemokine 11
Description Not Available
Synonyms
  1. Beta-R1
  2. H174
  3. I-TAC
  4. IP-9
  5. Interferon gamma-inducible protein 9
  6. Interferon-inducible T-cell alpha chemoattractant
  7. Small-inducible cytokine B11
Gene Name CXCL11
Protein Type Receptor
Biological Properties
General Function Involved in chemokine activity
Specific Function Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses
GO Classification
Component
extracellular region
Function
cytokine activity
chemokine activity
binding
protein binding
receptor binding
Process
immune system process
immune response
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:4
Locus 4q21.2
SNPs CXCL11
Gene Sequence 
>285 bp
ATGAGTGTGAAGGGCATGGCTATAGCCTTGGCTGTGATATTGTGTGCTACAGTTGTTCAA
GGCTTCCCCATGTTCAAAAGAGGACGCTGTCTTTGCATAGGCCCTGGGGTAAAAGCAGTG
AAAGTGGCAGATATTGAGAAAGCCTCCATAATGTACCCAAGTAACAACTGTGACAAAATA
GAAGTGATTATTACCCTGAAAGAAAATAAAGGACAACGATGCCTAAATCCCAAATCGAAG
CAAGCAAGGCTTATAATCAAAAAAGTTGAAAGAAAGAATTTTTAA
Protein Properties
Number of Residues 94
Molecular Weight 10364.5
Theoretical pI 10.63
Pfam Domain Function
Signals
  • ["1-21"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>C-X-C motif chemokine 11
MSVKGMAIALAVILCATVVQGFPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKI
EVIITLKENKGQRCLNPKSKQARLIIKKVERKNF
GenBank ID Protein 2580586
UniProtKB/Swiss-Prot ID O14625
UniProtKB/Swiss-Prot Entry Name CXL11_HUMAN
PDB IDs
GenBank Gene ID AF002985
GeneCard ID CXCL11
GenAtlas ID CXCL11
HGNC ID HGNC:10638
References
General References Not Available