| Identification |
|---|
| HMDB Protein ID
| CDBP02850 |
| Secondary Accession Numbers
| Not Available |
| Name
| Calsyntenin-2 |
| Description
| Not Available |
| Synonyms
|
- Alc-gamma
- Alcadein-gamma
|
| Gene Name
| CLSTN2 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| May modulate calcium-mediated postsynaptic signals |
| GO Classification
|
| Component |
| membrane |
| cell part |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| cell adhesion |
| cellular process |
| cell-cell adhesion |
| homophilic cell adhesion |
|
| Cellular Location
|
- Cell membrane
- Golgi apparatus membrane
- Endoplasmic reticulum membrane
- Single-pass type I membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3q23 |
| SNPs
| CLSTN2 |
| Gene Sequence
|
>2868 bp
ATGCTGCCTGGGCGGCTGTGCTGGGTGCCGCTCCTGCTGGCGCTGGGCGTGGGGAGCGGC
AGCGGCGGTGGCGGGGACAGCCGGCAGCGCCGCCTCCTCGCGGCTAAAGTCAATAAGCAC
AAGCCATGGATCGAGACTTCATATCATGGAGTCATAACTGAGAACAATGACACAGTCATT
TTGGACCCACCACTGGTAGCCCTGGATAAAGATGCACCGGTTCCTTTTGCAGGGGAAATC
TGTGCGTTCAAGATCCATGGCCAGGAGCTGCCCTTTGAGGCTGTGGTGCTCAACAAGACA
TCAGGAGAGGGCCGGCTCCGTGCCAAGAGCCCCATTGACTGTGAGTTGCAGAAGGAGTAC
ACATTCATCATCCAGGCCTATGACTGTGGTGCTGGGCCCCACGAGACAGCCTGGAAAAAG
TCACACAAGGCCGTGGTCCATATACAGGTGAAGGATGTCAACGAGTTTGCTCCCACCTTC
AAAGAGCCAGCCTACAAGGCTGTTGTGACGGAGGGCAAGATCTATGACAGCATTCTGCAG
GTGGAGGCCATTGACGAGGACTGCTCCCCACAGTACAGCCAGATCTGCAACTATGAAATC
GTCACCACAGATGTGCCTTTTGCCATCGACAGAAATGGCAACATCAGGAACACTGAGAAG
CTGAGCTATGACAAACAACACCAGTATGAGATCCTGGTGACCGCCTACGACTGTGGACAG
AAGCCCGCTGCTCAGGACACCCTGGTGCAGGTGGATGTGAAGCCAGTTTGCAAGCCTGGC
TGGCAAGACTGGACCAAGAGGATTGAGTACCAGCCTGGCTCCGGGAGCATGCCCCTGTTC
CCCAGCATCCACCTGGAGACGTGCGATGGAGCCGTGTCTTCCCTCCAGATCGTCACAGAG
CTGCAGACTAATTACATTGGGAAGGGTTGTGACCGGGAGACCTACTCTGAGAAATCCCTT
CAAAAGTTATGTGGAGCCTCCTCTGGCATCATTGACCTCTTGCCATCCCCTAGCGCTGCC
ACCAACTGGACTGCAGGACTGCTGGTGGACAGCAGTGAGATGATCTTCAAGTTTGACGGC
AGGCAGGGTGCCAAAGTCCCCGATGGGATTGTGCCCAAGAACCTGACCGATCAGTTCACC
ATCACCATGTGGATGAAACACGGCCCCAGCCCTGGTGTGAGAGCCGAGAAGGAAACCATC
CTCTGCAACTCAGACAAAACCGAAATGAACCGGCATCACTATGCCCTGTATGTGCACAAC
TGCCGCCTCGTCTTTCTCTTGCGGAAGGACTTCGACCAGGCTGACACCTTTCGCCCCGCG
GAGTTCCACTGGAAGCTGGATCAGATTTGTGACAAAGAGTGGCACTACTATGTCATCAAT
GTGGAGTTTCCTGTGGTAACCTTATACATGGATGGAGCAACATATGAACCATACCTGGTG
ACCAACGACTGGCCCATTCATCCATCTCACATAGCCATGCAACTCACAGTCGGCGCTTGT
TGGCAAGGAGGAGAAGTCACCAAACCACAGTTTGCTCAGTTCTTTCATGGAAGCCTGGCC
AGTCTCACCATCCGCCCTGGCAAAATGGAAAGCCAGAAGGTGATCTCCTGCCTGCAGGCC
TGCAAGGAAGGGCTGGACATTAATTCCTTGGAAAGCCTTGGCCAAGGAATAAAGTATCAC
TTCAACCCCTCGCAGTCCATCCTGGTGATGGAAGGTGACGACATTGGGAACATTAACCGT
GCTCTCCAGAAAGTCTCCTACATCAACTCCAGGCAGTTCCCAACGGCGGGTGTGCGGCGC
CTCAAAGTATCCTCCAAAGTCCAGTGCTTTGGGGAAGACGTATGCATCAGTATCCCTGAG
GTAGATGCCTATGTGATGGTCCTCCAGGCCATCGAGCCCCGGATCACCCTCCGGGGCACA
GACCACTTCTGGAGACCTGCTGCCCAGTTTGAAAGTGCCAGGGGAGTGACCCTCTTCCCT
GATATCAAGATTGTGAGCACCTTCGCCAAAACCGAAGCCCCCGGGGACGTGAAAACCACA
GACCCCAAATCAGAAGTCTTAGAGGAAATGCTTCATAACTTAGATTTCTGTGACATTTTG
GTGATCGGAGGGGACTTGGACCCAAGGCAGGAGTGCTTGGAGCTCAACCACAGTGAGCTC
CACCAACGACACCTGGATGCCACTAATTCTACTGCAGGCTACTCCATCTACGGTGTGGGC
TCCATGAGCCGCTATGAGCAGGTGCTACATCACATCCGCTACCGCAACTGGCGTCCGGCT
TCCCTTGAGGCCCGGCGTTTCCGGATTAAGTGCTCAGAACTCAATGGGCGCTACACTAGC
AATGAGTTCAACTTGGAGGTCAGCATCCTTCATGAAGACCAAGTCTCAGATAAGGAGCAT
GTCAATCATCTGATTGTGCAGCCTCCCTTCCTCCAGTCTGTCCATCATCCTGAGTCCCGG
AGTAGCATCCAGCACAGTTCAGTGGTCCCAAGCATTGCCACAGTGGTCATCATCATCTCC
GTGTGCATGCTTGTGTTTGTCGTGGCCATGGGTGTGTACCGGGTCCGGATCGCCCACCAG
CACTTCATCCAGGAGACTGAGGCTGCCAAGGAATCTGAGATGGACTGGGACGATTCTGCG
CTGACTATCACAGTCAACCCCATGGAGAAACATGAAGGACCAGGGCATGGGGAAGATGAG
ACTGAGGGAGAAGAGGAGGAAGAAGCCGAGGAAGAAATGAGCTCCAGCAGTGGCTCTGAC
GACAGCGAAGAGGAGGAGGAGGAGGAAGGGATGGGCAGAGGCAGACATGGGCAGAATGGA
GCCAGGCAAGCCCAGCTGGAGTGGGATGACTCCACCCTCCCCTACTAG
|
| Protein Properties |
|---|
| Number of Residues
| 955 |
| Molecular Weight
| 107004.9 |
| Theoretical pI
| 5.07 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Calsyntenin-2
MLPGRLCWVPLLLALGVGSGSGGGGDSRQRRLLAAKVNKHKPWIETSYHGVITENNDTVI
LDPPLVALDKDAPVPFAGEICAFKIHGQELPFEAVVLNKTSGEGRLRAKSPIDCELQKEY
TFIIQAYDCGAGPHETAWKKSHKAVVHIQVKDVNEFAPTFKEPAYKAVVTEGKIYDSILQ
VEAIDEDCSPQYSQICNYEIVTTDVPFAIDRNGNIRNTEKLSYDKQHQYEILVTAYDCGQ
KPAAQDTLVQVDVKPVCKPGWQDWTKRIEYQPGSGSMPLFPSIHLETCDGAVSSLQIVTE
LQTNYIGKGCDRETYSEKSLQKLCGASSGIIDLLPSPSAATNWTAGLLVDSSEMIFKFDG
RQGAKVPDGIVPKNLTDQFTITMWMKHGPSPGVRAEKETILCNSDKTEMNRHHYALYVHN
CRLVFLLRKDFDQADTFRPAEFHWKLDQICDKEWHYYVINVEFPVVTLYMDGATYEPYLV
TNDWPIHPSHIAMQLTVGACWQGGEVTKPQFAQFFHGSLASLTIRPGKMESQKVISCLQA
CKEGLDINSLESLGQGIKYHFNPSQSILVMEGDDIGNINRALQKVSYINSRQFPTAGVRR
LKVSSKVQCFGEDVCISIPEVDAYVMVLQAIEPRITLRGTDHFWRPAAQFESARGVTLFP
DIKIVSTFAKTEAPGDVKTTDPKSEVLEEMLHNLDFCDILVIGGDLDPRQECLELNHSEL
HQRHLDATNSTAGYSIYGVGSMSRYEQVLHHIRYRNWRPASLEARRFRIKCSELNGRYTS
NEFNLEVSILHEDQVSDKEHVNHLIVQPPFLQSVHHPESRSSIQHSSVVPSIATVVIIIS
VCMLVFVVAMGVYRVRIAHQHFIQETEAAKESEMDWDDSALTITVNPMEKHEGPGHGEDE
TEGEEEEEAEEEMSSSSGSDDSEEEEEEEGMGRGRHGQNGARQAQLEWDDSTLPY
|
| External Links |
|---|
| GenBank ID Protein
| 209364544 |
| UniProtKB/Swiss-Prot ID
| Q9H4D0 |
| UniProtKB/Swiss-Prot Entry Name
| CSTN2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_022131.2 |
| GeneCard ID
| CLSTN2 |
| GenAtlas ID
| CLSTN2 |
| HGNC ID
| HGNC:17448 |
| References |
|---|
| General References
| Not Available |