| Identification |
|---|
| HMDB Protein ID
| CDBP02834 |
| Secondary Accession Numbers
| Not Available |
| Name
| Coactosin-like protein |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| COTL1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in actin binding |
| Specific Function
| Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Function |
| binding |
| protein binding |
| cytoskeletal protein binding |
| actin binding |
|
| Cellular Location
|
- Cytoplasm
- cytoskeleton
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 16q24.1 |
| SNPs
| COTL1 |
| Gene Sequence
|
>429 bp
ATGGCCACCAAGATCGACAAAGAGGCTTGCCGGGCGGCGTACAACCTGGTGCGCGACGAC
GGCTCGGCCGTCATCTGGGTGACTTTTAAATATGACGGCTCCACCATCGTCCCCGGCGAG
CAGGGAGCGGAGTACCAGCACTTCATCCAGCAGTGCACAGATGACGTCCGGTTGTTTGCC
TTCGTGCGCTTCACCACCGGGGATGCCATGAGCAAGAGGTCCAAGTTTGCCCTCATCACG
TGGATCGGTGAGAACGTCAGCGGGCTGCAGCGCGCCAAAACCGGGACGGACAAGACCCTG
GTGAAGGAGGTCGTACAGAATTTCGCTAAGGAGTTTGTGATCAGTGATCGGAAGGAGCTG
GAGGAAGATTTCATCAAGAGCGAGCTGAAAAAGGCGGGGGGAGCCAATTACGACGCCCAG
ACGGAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 142 |
| Molecular Weight
| 15944.9 |
| Theoretical pI
| 5.31 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Coactosin-like protein
MATKIDKEACRAAYNLVRDDGSAVIWVTFKYDGSTIVPGEQGAEYQHFIQQCTDDVRLFA
FVRFTTGDAMSKRSKFALITWIGENVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKEL
EEDFIKSELKKAGGANYDAQTE
|
| External Links |
|---|
| GenBank ID Protein
| 189055056 |
| UniProtKB/Swiss-Prot ID
| Q14019 |
| UniProtKB/Swiss-Prot Entry Name
| COTL1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AK315675 |
| GeneCard ID
| COTL1 |
| GenAtlas ID
| COTL1 |
| HGNC ID
| HGNC:18304 |
| References |
|---|
| General References
| Not Available |